Article
Microbiology
Jaime Rosas-Diaz, Alejandra Escobar-Zepeda, Libertad Adaya, Jorge Rojas-Vargas, Diego Humberto Cuervo-Amaya, Ayixon Sanchez-Reyes, Liliana Pardo-Lopez
Summary: Paenarthrobacter sp. GOM3 is a new strain with a unique species-specific background that can grow independently in marine sediments and participate in the degradation of intermediate metabolites of aromatic compounds, showing potential for remediation of PAH-contaminated sites.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Lijuan Feng, Yan Qiao, Changyan Xiao, Dongzhi Chen
Summary: The antibacterial activity of seaweed against Vibrio strains was examined, and the seaweed species Ulva fasciata showed the strongest inhibition. The stress caused by Vibrio strains also led to changes in gene expression in Ulva fasciata and the enrichment of endophytic bacteria.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Chemistry, Multidisciplinary
Mohd Ridzwan Jusidin, Rafidah Othman, Sitti Raehanah Muhamad Shaleh, Fui Fui Ching, Shigeharu Senoo, Siti Nur Hazwani Oslan
Summary: The potential application of N. oceanica, Isochrysis sp., and T. weissflogii as inhibitory bacteria and probiotics in controlling bacterial diseases in the aquaculture industry is investigated. Marine microalgae were found to produce antibacterial substances, with N. oceanica exhibiting the largest inhibitory zone against V. harveyi. These findings suggest that the hydrophilic chemicals in microalgae extracts have antibiotic activity against the highly virulent V. harveyi, providing potential solutions for preventing vibriosis in aquaculture.
APPLIED SCIENCES-BASEL
(2022)
Article
Fisheries
Neda Fazeli, Seyed Amir Hossein Jalali, Akram Sadat Naeemi, Hojjatolah Zamani
Summary: The overuse of antibiotics in the fish farming industry has led to an increase in bacterial resistance. In this study, the antibacterial and anti-biofilm properties of sea anemone-isolated bacteria against Yersinia ruckeri were evaluated. It was found that a Vibrio parahaemolyticus extract displayed the most efficient activity against Yersinia ruckeri and affected biofilm formation.
AQUACULTURE INTERNATIONAL
(2022)
Review
Biochemistry & Molecular Biology
Rodion Khotimchenko, Igor Bryukhovetskiy, Maksim Khotimchenko, Yuri Khotimchenko
Summary: The study reviews the outcomes of screening studies of natural compounds with high anti-glioma activity, emphasizing the potential for greater diversity of marine compounds and likelihood of finding effective molecules. It covers the main problems of glioma chemotherapy and provides information on at least 15 classes of organic compounds with their chemical formulas and pharmacokinetic profiles. The taxonomic diversity of marine species containing bioactives with antiglioma activity is analyzed, noting cytotoxicity indicators and comparing them to similar indicators of antitumor agents for clinical use.
Article
Marine & Freshwater Biology
V. Santhana Lakshmi, S. Ranjani, S. Hemalatha
Summary: The presence of Vibrio parahaemolyticus, Vibrio alginolyticus, and Vibrio harveyi in aquatic organisms causes vibriosis, leading to high mortality. Antibiotic treatment is becoming less effective due to increasing antibiotic resistance, making alternative therapeutic agents necessary. This study focuses on using bioactive compounds from Cymbopogon citratus to promote growth, natural immune response, and disease resistance against pathogenic bacteria. In silico studies were conducted to evaluate the binding potential of these compounds against targeted proteins in Vibrio parahaemolyticus and Vibrio alginolyticus. Nanoparticles synthesized from Cymbopogon citratus showed non-toxicity and exhibited antibacterial activity against Vibrio species.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Christian Mark Garcia Salvador, Rongzhi Tang, Michael Priestley, Linjie Li, Epameinondas Tsiligiannis, Michael Le Breton, Wenfei Zhu, Limin Zeng, Hui Wang, Ying Yu, Min Hu, Song Guo, Mattias Hallquist
Summary: Nitro-aromatic compounds (NACs) were measured hourly in a rural site in China during wintertime. The study found that NACs may significantly contribute to the radiative forcing effects of atmospheric particles. Additionally, gas-phase NAC levels were highest during the daytime, and regional secondary processes played a significant role in NAC concentrations.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2021)
Article
Engineering, Environmental
Aadil Ahmad Aullybux, Daneshwar Puchooa, Theeshan Bahorun, Rajesh Jeewon, Xuesong Wen, Poona Matin
Summary: The sulphated EPS from Alcaligenes faecalis showed high DPPH scavenging activity and low ferric reducing capacity, with HepG2 and A549 cells being the most susceptible to its cytotoxic effects. Conversely, CaSki, HeLa, and C33A cells showed resistance, with C33A exhibiting higher inhibition likely due to the absence of viral proteins.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Environmental Sciences
Junjie Wang, Zhigang Li, Shaoyang Hu, Jian Ma, Tingting Gong, Qiming Xian
Summary: This study investigated the formation of chloro-nitromethanes during chlorination and chloramination of nitro-aromatic compounds, revealing 2-nitrophenol and 3-nitrophenol as main precursors. Chlorination led to higher HNMs formation compared to chloramination, while ferric and manganese ions had different impacts on TCNM formation. Nitrite was found to significantly reduce TCNM formation, indicating different effects on TCNM formation from different precursors. Additionally, dissolved organic matter significantly influenced TCNM formation in chlorination of 2-nitrophenol, despite low TCNM formation in chlorination of DOM.
Article
Fisheries
Jie Hu, Cang Wang, Hangtian Zu, Zaixi Fang, Haolong Zhou, Junlan Zhou, Shujun Wang, Mingsheng Lyu
Summary: This study investigated the effects of Nano-SiO2, ultraviolet (UV) irradiation, and hydrogen peroxide on the growth of four marine aquatic pathogens. Nano-SiO2 demonstrated the most inhibition of Edwardsiella tarda, Vibrio anguillarum, and Vibrio parahaemolyticus. UV irradiation had an inhibitory effect on E. tarda, while hydrogen peroxide inhibited the growth of all bacterial strains.
AQUACULTURE REPORTS
(2022)
Article
Chemistry, Organic
Didier F. Vargas, Teodoro S. Kaufman, Enrique L. Larghi
Summary: The first total synthesis of marine alkaloid aqabamycin G was disclosed, involving addition to maleimide of an indole motif and a substituted diazo-benzenoid unit derived from acetaminophen. An alternative strategy using a protected phenol was also reported.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Marie Champion, Emilie Portier, Karine Vallee-Rehel, Isabelle Linossier, Eric Balnois, Guillaume Vignaud, Xavier Moppert, Claire Hellio, Fabienne Fay
Summary: Biofilms can cause serious issues in medical and marine environments, and current anti-biofilm solutions that use biocides come with the risk of antibiotic resistance and pollution. Therefore, there is a need for ecofriendly solutions that rely on the anti-adhesive properties of materials. This study focuses on the effect of a specific exopolysaccharide on the growth and dispersion of pathogenic model strains, and the results show that it can limit biofilm formation without any biocidal activity.
Article
Plant Sciences
Carla de Fatima Alves Nonato, Emerson Vinicius Silva de Melo, Cicera Janaine Camilo, Maria Kueirislene Amancio Ferreira, Jane Eire Alencar de Meneses, Antonio Wlisses da Silva, Helcio Silva dos Santos, Jaime Ribeiro-Filho, Joanda Paolla Raimundo e Silva, Josean Fechine Tavares, Irwin Rose Alencar de Menezes, Henrique Douglas Melo Coutinho, Grazyna Kowalska, Tomasz Baj, Radoslaw Kowalski, Jose Galberto Martins da Costa
Summary: This study evaluated the antibacterial and anxiolytic effects of essential oils and ethanolic extracts from three species of Lippia (L. alba, L. sidoides, and L. gracilis). The extracts showed significant antibacterial activity, especially those from L. sidoides, and L. alba extract presented the most significant antibiotic-enhancing effect. Additionally, the extracts exhibited anxiolytic effects through modulation of the GABA(A) and 5-HT receptors. These findings provide new pharmacological evidence for potential therapeutic approaches and food preservation using Lippia species.
Article
Plant Sciences
Shachi Singh, Mukesh Kumar, Seema Dwivedi, Anjali Yadav, Sarika Sharma
Summary: In this study, a rapid and effective metabolomic method was used to screen the chemical characterization of all parts of B. prionitis, including leaf, root, stem, and inflorescence. Bioactive iridoid glycosides and phenolic compounds were identified in all parts, with root showing the highest antioxidant and antibacterial activity. Some of the identified compounds were positively correlated with the tested biological activity. Principal component analysis of the chemical profiles revealed variability in compound distribution.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Venke Kristoffersen, Marte Jenssen, Heba Raid Jawad, Johan Isaksson, Espen H. Hansen, Teppo Rama, Kine O. Hansen, Jeanette Hammer Andersen
Summary: Through chemical studies of bacteria belonging to the Lacinutrix genus, two novel isobranched lyso-ornithine lipids were identified, with compound 1 exhibiting antibacterial activity, while compound 2 showed cytotoxic activity against human melanoma cells.
Article
Chemistry, Multidisciplinary
Muhammad Ashram, Ghassab M. Al-Mazaideh, Wael Al-Zereini, Ahmed Al-Mustafa, Shehadeh Mizyed
JOURNAL OF SULFUR CHEMISTRY
(2019)
Article
Chemistry, Inorganic & Nuclear
Muhammad Ashram, Ahmed Al-Mustafa, Wael A. Al-Zereini, Firas F. Awwadi, Islam Ashram
Summary: Pyrazino[1,2-a]indoles fused with various heterocycles were synthesized via transition metal-free domino reactions, leading to the formation of new interesting fused heterocycles. Some compounds exhibited potent inhibitory activity against AChE and strong antioxidant properties, but showed weak to moderate antibacterial activities against Gram-positive bacteria.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Wael A. Al-Zereini, Ibrahim N. Al-Trawneh, Mahmoud A. Al-Qudah, Heba M. TumAllah, Zead H. Abudayeh, Tahani Hijazin
Summary: This study found that the essential oil extracted from clove buds (CEO) has antibacterial, antioxidant, and cytotoxic activities. The main compound in CEO is eugenol, which inhibits the growth of both Gram-positive and Gram-negative bacterial strains and exhibits antioxidant properties and cytotoxicity against cancerous and noncancerous cells.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
(2023)
Article
Pharmacology & Pharmacy
Abdalrahim Alahmad, Wael A. Al-Zereini, Tahani J. Hijazin, Osama Y. Al-Madanat, Ibrahim Alghoraibi, Omar Al-Qaralleh, Samer Al-Qaraleh, Armin Feldhoff, Johanna-Gabriela Walter, Thomas Scheper
Summary: Silver nanoparticles prepared with silver nitrate and hot St. John's wort extract showed antibacterial activity against both Gram-positive and Gram-negative bacterial strains, highlighting their potential applications in pharmaceutical and food industries.
Article
Chemistry, Applied
Khaleel A. Abu-Sbeih, Ghassab M. Al-Mazaideh, Wael A. Al-Zereini
Summary: Chitosan, derived from chitin, was fragmented using zeolites and molecular sieves under variable reaction conditions. The prepared chitosan oligomers showed antibacterial activity against Gram-positive bacteria.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Medicinal
Ahmed Al-Mustafa, Wael Al-Zereini, Muhammad Ashram, Mahmoud A. Al-Sha'er
Summary: This study evaluated the antioxidant, antibacterial, cytotoxic, and anti-cholinesterase activities of 1,4-benzoxazepine derivatives and confirmed their biological activities through molecular modeling. The compounds showed potential anti-breast cancer and antibacterial activities, as well as antioxidant properties.
MEDICINAL CHEMISTRY RESEARCH
(2023)
Article
Microbiology
Mohammad A. Abu-Lubad, Wael Al-Zereini, Munir A. Al-Zeer
Summary: The effect of Chlamydia trachomatis (Ctr) infection on the expression of the cell cycle regulator protein p27 in mesenchymal stem cells (MSCs) was investigated in this study. MSCs were isolated from healthy human fallopian tube and the expression of p27 was measured at the protein level. The results showed that Ctr infection downregulated the expression of p27 and may lead to transformation in Ctr-infected MSCs.
Article
Chemistry, Applied
Samer Y. Al-Qaraleh, Wael A. Al-Zereini, Sawsan A. Oran
Summary: This study synthesized selenium nanoparticles using Moringa peregrina leaves extract. The nanoparticles showed antibacterial, antioxidant, and anti-proliferative activities against breast cancer cells. These findings suggest that the nanoparticles could have potential applications in green synthesis of chemotherapeutic drugs and in the food and pharmaceutical industries.
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY
(2023)
Article
Plant Sciences
Mahmoud A. Al-Qudah, Rawia S. Migdadi, Abdulraouf S. Mayyas, Wael A. Al-Zereini, Yousef Al-Dalahmeh, Faten M. Abu Orabi, Tareq T. Bataineh, Sultan T. Abu-Orabi
Summary: The essential oils from flowers and leaves of P. incisa and P. crispa were extracted using two methods, hydro-distillation and solid phase micro-extraction. The analysis showed that these essential oils demonstrated good antioxidant and anticancer activities.
JOURNAL OF ESSENTIAL OIL BEARING PLANTS
(2022)
Article
Pharmacology & Pharmacy
Wael A. Al-Zereini, Ibrahim N. Al-Trawneh, Mahmoud A. Al-Qudah, Heba M. TumAllah, Hamas A. Al Rawashdeh, Zaed H. Abudayeh
Summary: The essential oils extracted from Cinnamomum verum and Elettaria cardamomum showed antibacterial and antioxidant activities, as well as cytotoxic effects against breast cancer cells. These findings suggest the potential use of Cinnamomum verum and Elettaria cardamomum in complementary and alternative medicine as safe remedies.
JOURNAL OF PHARMACY & PHARMACOGNOSY RESEARCH
(2022)
Article
Pharmacology & Pharmacy
Omar S. Al-Qaralleh, Wael A. Al-Zereini, Ahmed H. Al-Mustafa
Summary: The crude extract of Fusarium sp. isolate OQ-Fus-2-F shows potential biomedical applications with antimicrobial, antioxidant, and neuroprotective activities. It displayed strong inhibition of B. subtilis growth and had significant antioxidant activity, particularly in the ABTS method. Additionally, the extract effectively inhibited acetylcholinesterase activity.
JOURNAL OF PHARMACY & PHARMACOGNOSY RESEARCH
(2021)
Article
Immunology
Tahany Saleem Al-Hajaya, Wael Ali Al-Zereini, Hesham Mahmoud Al-Younes
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY
(2020)
Article
Parasitology
B. Al Fraijat, N. M. Al-Tawarah, A. M. Khlaifat, H. Qaralleh, K. M. Khleifat, W. Al-Zereini, M. O. Al-limotm
TROPICAL BIOMEDICINE
(2019)
Article
Medicine, General & Internal
Mohammad A. Abu-Lubad, Hamed M. Alzoubi, Wael Al-zereini, Dua'a A. K. Jarajreh, Fawzieh Alhjooj, Amin A. Aqel
RAWAL MEDICAL JOURNAL
(2020)
Article
Biochemistry & Molecular Biology
Fuad Al-Rimawi, Fadi Alakhras, Wael A. Al-Zereini, Hammad K. Aldal'in, Saleh Abu-Lafi, Ghassab M. Al-Mazaideh, Haya J. Ayyal Salman
ORIENTAL JOURNAL OF CHEMISTRY
(2018)