Article
Polymer Science
Yuchen Liu, Ming Fang, Ruifeng Zhao, Hengyan Liu, Min Tian, Sheng Zhong, Shizhu Bai
Summary: This study evaluated the effect of periodontal splints made from different materials on stress distributions in compromised periodontal tissues and cement layers. Using a computer simulation of mastication, it was found that the use of splints effectively distributed loads and reduced stress. Splinting materials with low elastic moduli reduced stress concentration at the connectors, but increased tensile stress in the cement layer.
Article
Computer Science, Interdisciplinary Applications
Tinghui Sun, Desmond Y. R. Chong, Bingmei Shao, Zhan Liu
Summary: This study aims to investigate the biomechanical behavior of the human masticatory system and reveal the force transmission patterns using advanced three-dimensional finite element models. The results showed that the molar occlusal surfaces play a primary role in force transmission during clenching. The presence or absence of molar cushions significantly affects the biomechanical response of the masticatory system. This study contributes to a better understanding of force transmission and the significance of temporomandibular joints during the clenching process.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ming-Tzu Tsai, Heng-Li Huang, Shih-Guang Yang, Kuo-Chih Su, Lih-Jyh Fuh, Jui-Ting Hsu
Summary: The study investigated four common occlusal modes using the finite element method and analyzed the biomechanics of the periodontal ligament and surrounding bone when orthodontic force is applied. Results showed that occlusal mode strongly influenced von Mises strain in the canine periodontal ligaments, but had smaller effects on strain distribution in cortical bone, cancellous bone, and miniscrews.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Critical Care Medicine
Yilmaz Guvercin, Murat Yaylaci, Ayberk Dizdar, Ayhan Kanat, Ecren Uzun Yaylaci, Sevil Ay, Ahmet Atilla Abdioglu, Ahmet Sen
Summary: This study investigates the effect of neck movements on the odontoid and transverse atlantal ligament of people with Ponticulus posticus (PP) variation from a biomechanical perspective. The study finds that individuals with PP variation are more susceptible to stress and deformation in the odontoid, potentially explaining the pathogenesis of odontoid fractures in older adults.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Article
Engineering, Environmental
Rui Wang, Li Liao, Xiaojun Huang, Shixing Ma, Shuang Wang, Hu Qiao, Hong Zhou, Jing Zou, Xiaoxia Su
Summary: Mechanical stimulation can enhance the osteogenic properties of exosomes secreted by PDLSCs through the upregulation of miR-200b/c. These miRNAs target Smurf1 to activate the BMP-Smad signaling pathway and promote osteogenic differentiation of mandibular BMSCs. Functionalized exosomes containing miR-200b/c can effectively promote the repair of alveolar bone defects in a rat model, providing a novel therapeutic approach for inflammatory bone loss in periodontitis.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Qiusheng Shi, Lisha Zheng, Jing Na, Xinyang Li, Zhijie Yang, Xinyuan Chen, Yaxin Song, Chiyu Li, Lulin Zhou, Yubo Fan
Summary: This study finds that appropriate flow shear stress promotes the proliferation of periodontal ligament (PDL) cells. Flow shear stress remodels the cytoskeleton and focal adhesion of PDL cells and activates the p38-AMOT-YAP signaling pathway to regulate cell proliferation and nuclear translocation.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Radu-Andrei Moga, Stefan Marius Buru, Cosmin Gruia Chiorean
Summary: This research aimed to assess the stress in the periodontal ligament during gradual periodontal breakdown under orthodontic movements, and analyze the correlations between applied forces, bone loss, force magnitude, and stress increase. The study found that rotation and translation induced the highest stress, while intrusion determined the lowest. A force of 1.2 N seemed safe in intact periodontium, while forces higher than 0.6 N could endanger the reduced periodontium.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2022)
Article
Chemistry, Multidisciplinary
Cristina Bucchi, Massimo Del Fabbro, Jordi Marce-Nogue
Summary: This study utilized finite element analysis to investigate the stress distribution in tooth structures under orthodontic loads, finding that mature teeth with dentine or cementum reinforcement have reduced stress values in the periodontal ligament, indicating safe orthodontic treatment. Further in vivo studies will be important to validate these findings.
APPLIED SCIENCES-BASEL
(2022)
Article
Orthopedics
Bing Wang, Yongjie Ye, Long Yao, Ancheng Wei, Xin Huang, Zhiqiang Wang, Xiaojun Yu
Summary: There is currently no consensus on the optimal biomechanical method for PCL reconstruction, and the critical corner produced by the femoral tunnel is considered a main reason for PCL failure. This study aimed to identify different femoral tunnels to reduce the influence of the critical corner without reducing the posterior stability of the knee joint.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Computer Science, Interdisciplinary Applications
Jianlei Wu, Yunfeng Liu, Boxiu Li, Xingtao Dong
Summary: This study successfully developed a constitutive model for human periodontal ligament (PDL) by combining hyperelastic and viscosity models, and validated it through finite element analysis (FEA). The results showed good agreement between simulative and experimental data, providing valuable insights for orthodontists to understand the biomechanical characteristics of PDL.
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2022)
Article
Medicine, General & Internal
Mahmoud Katta, Stelian-Mihai-Sever Petrescu, Lucian Paul Dragomir, Mihai Raul Popescu, Ruxandra Voinea Georgescu, Mihaela Jana Tculina, Dragos Laurenbiu Popa, Alina Duba, Oana Andreea Diaconu, Ionela Teodora Dascalu
Summary: The finite element method is used to simulate the behavior of a real orthodontic system subjected to different systems of loads. The InVesalius program is used to transform CBCT images into 3D structures, which are then analyzed using Geomagic software. The resulting 3D model is loaded into CAD programs and additional components like brackets and wires are added. The simulation using FEM is performed to determine the behavior of the orthodontic system under different forces, and the results show displacement, strain, and stress diagrams.
Article
Dentistry, Oral Surgery & Medicine
Maria Alicia Frias Cortez, Christoph Bourauel, Christoph Reichert, Andreas Jaeger, Susanne Reimann
Summary: The study suggests that higher forces may cause extreme strains in periodontally compromised dentition, while lower forces using cantilever mechanics for en masse retraction show better results. Careful planning and reduction of applied forces are recommended to address increased periodontal stresses in severe attachment loss.
JOURNAL OF OROFACIAL ORTHOPEDICS-FORTSCHRITTE DER KIEFERORTHOPADIE
(2022)
Article
Dentistry, Oral Surgery & Medicine
K. P. Houg, A. M. Camarillo, M. R. Doschak, P. W. Major, T. Popowics, C. R. Dennison, D. L. Romanyk
Summary: In this study, the use of in-fiber Bragg grating (FBG) sensors to measure the strain of ex vivo periodontal ligament (PDL) was investigated. The experimental results showed that the FBG sensor can be used to measure strain changes and monitor the mechanical properties of intact PDL over time, providing valuable insights for dental research.
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Gustavo Hauber Gameiro, Jorge Eugenio Bocchiardo, Michel Dalstra, Paolo Maria Cattaneo
Summary: The orthodontic correction of periodontally compromised dentitions poses a significant challenge in adult orthodontic practice, requiring carefully designed mechanical plans. Tooth displacements and periodontal ligament strains are higher in compromised dentitions, indicating a need to reduce force levels and customize force application points based on the degree of alveolar bone loss.
ORTHODONTICS & CRANIOFACIAL RESEARCH
(2021)
Review
Endocrinology & Metabolism
Paolo M. Cattaneo, Marie A. Cornelis
Summary: Finite element (FE) analysis shows great potential in studying orthodontic tooth movement (OTM), helping to understand the impact of alveolar complexity and material properties, and predicting the risk of root resorption related to specific force systems and magnitudes. Recent findings challenge the simplified view of traditional OTM theories.
CURRENT OSTEOPOROSIS REPORTS
(2021)
Article
Plant Sciences
Maria Pierantoni, Ron Tenne, Batel Rephael, Vlad Brumfeld, Adam van Casteren, Kornelius Kupczik, Dan Oron, Lia Addadi, Steve Weiner
Article
Dentistry, Oral Surgery & Medicine
Julian Balanta-Melo, Maria Angelica Torres-Quintana, Maximilian Bemmann, Carolina Vega, Constanza Gonzalez, Kornelius Kupczik, Viviana Toro-Ibacache, Sonja Buvinic
JOURNAL OF ORAL REHABILITATION
(2019)
Article
Biology
Alejandro Perez-Ramos, Kornelius Kupczik, Anneke H. Van Heteren, Gernot Rabeder, Aurora Grandal-D'Anglade, Francisco J. Pastor, Francisco J. Serrano, Borja Figueirido
HISTORICAL BIOLOGY
(2019)
Article
Anthropology
Ellen Schulz-Kornas, Julia Stuhltraeger, Marcus Clauss, Roman M. Wittig, Kornelius Kupczik
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2019)
Review
Food Science & Technology
Julian Balanta-Melo, Viviana Toro-Ibacache, Kornelius Kupczik, Sonja Buvinic
Article
Anthropology
Kornelius Kupczik, Lucas K. Delezene, Matthew M. Skinner
JOURNAL OF HUMAN EVOLUTION
(2019)
Article
Multidisciplinary Sciences
Michael A. Berthaume, Julia Winchester, Kornelius Kupczik
Article
Multidisciplinary Sciences
Michael A. Berthaume, Julia Winchester, Kornelius Kupczik
Article
Anthropology
Adam van Casteren, Edward Wright, Kornelius Kupczik, Martha M. Robbins
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2019)
Letter
Multidisciplinary Sciences
Shara E. Bailey, Kornelius Kupczik, Jean-Jacques Hublin, Susan C. Anton
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2020)
Article
Multidisciplinary Sciences
Julia Stuhltraeger, Ellen Schulz-Kornas, Ottmar Kullmer, Marcel M. Janocha, Roman M. Wittig, Kornelius Kupczik
Summary: This study combines macroscopic and microscopic wear analyses to explore tooth use differences between historical western chimpanzees from Liberia and the extant chimpanzees of Ta1 National Park in Ivory Coast. The results indicate similar long-term feeding behavior but significant short-term differences between the populations, potentially linked to historical events during dry periods in Liberia. Furthermore, differences in 3D surface textures between Liberian males and females suggest a higher consumption of insects by females, in line with patterns observed in Ta1 chimpanzees.
Article
Anthropology
Robert C. Power, Roman M. Wittig, Jeffery R. Stone, Kornelius Kupczik, Ellen Schulz-Kornas
Summary: By analyzing phytoliths in chimpanzee fecal samples, researchers can assess how plant phytoliths in the diet are reflected in dental calculus and feces, improving research strategies and providing valuable information for future studies.
ARCHAEOLOGICAL AND ANTHROPOLOGICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Adam van Casteren, Jonathan R. Codd, Kornelius Kupczik, Guy Plasqui, William Sellers, Amanda G. Henry
Summary: Chewing different items can result in varying metabolic costs, and chewing by human subjects represents a measurable energy sink. Chewing tasteless and odorless gum increases metabolic rate, with energy expenditure increasing with gum stiffness and requiring greater muscle recruitment. This adds an previously unexplored energetic dimension to the interpretation of hominin dentofacial fossils.
Article
Biochemistry & Molecular Biology
Julian Balanta-Melo, Andrea Eyquem-Reyes, Noelia Blanco, Walter Vasquez, Kornelius Kupczik, Viviana Toro-Ibacache, Sonja Buvinic
Summary: Research on mice found that unilateral muscle dysfunction can lead to atrophy signs in the affected muscle and other masticatory muscles. This study suggests the need for further clinical research to determine the safety of botulinum toxin type A in dental practice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biology
Michael A. Berthaume, Kornelius Kupczik
Summary: This study quantified the molar biomechanical performance of two Plio-Pleistocene hominins, Paranthropus robustus and Australopithecus africanus, to investigate potential dietary differences between them. The results showed that Paranthropus robustus required more force and energy to fracture food items but had a higher force transmission rate. Three evolutionary scenarios concerning the dietary ecologies of these hominins were proposed based on the findings, highlighting the importance of a holistic approach to reconstructing hominin dietary ecology.