Micronucleus formation by single and mixed heavy metals/loids and PAH compounds in HepG2 cells

Metal–PAH mixtures in the aquatic environment: A review of co-toxic mechanisms leading to more-than-additive outcomes

(2014) Patrick T. Gauthier et al.   AQUATIC TOXICOLOGY

Human Aldo-Keto Reductases and the Metabolic Activation of Polycyclic Aromatic Hydrocarbons

(2014) Trevor M. Penning   CHEMICAL RESEARCH IN TOXICOLOGY

Systems Toxicology Approach to Understand the Kinetics of Benzo(a)pyrene Uptake, Biotransformation, and DNA Adduct Formation in a Liver Cell Model

(2014) Danielle J. Madureira et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bioavailability and pharmacokinetics of arsenic are influenced by the presence of cadmium

(2014) Violet Diacomanolis et al.   CHEMOSPHERE

AhR-mediated activities of polycyclic aromatic compound (PAC) mixtures are predictable by the concept of concentration addition

(2014) Maria Larsson et al.   ENVIRONMENT INTERNATIONAL

Developmental toxicity of PAH mixtures in fish early life stages. Part II: adverse effects in Japanese medaka

(2014) Florane Le Bihanic et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

A novel electrochemical method to evaluate the cytotoxicity of heavy metals

(2014) Xiaolin Zhu et al.   JOURNAL OF HAZARDOUS MATERIALS

Benzo[a]pyrene increases DNA double strand break repair in vitro and in vivo: A possible mechanism for benzo[a]pyrene-induced toxicity

(2014) Emily W.Y. Tung et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Interactions between polycyclic aromatic hydrocarbons in complex mixtures and implications for cancer risk assessment

(2014) Ian W.H. Jarvis et al.   TOXICOLOGY

Pollution of Flooded Arable Soils with Heavy Metals and Polycyclic Aromatic Hydrocarbons (PAHs)

(2014) Tomasz Ciesielczuk et al.   WATER AIR AND SOIL POLLUTION

Aqueous phenanthrene toxicity after high-frequency ultrasound degradation

(2013) Stefanos Dailianis et al.   AQUATIC TOXICOLOGY

Study on the In Vitro Effects of the Mixtures of Polycyclic Aromatic Hydrocarbons (PAHs) and Heavy Metals on Ethoxyresorufin-O-Deethylase (EROD) Activity in Mossambica tilapia Liver

(2013) Da Xiong Han et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Assessing the combined risks of PAHs and metals in urban soils by urbanization indicators

(2013) Chi Peng et al.   ENVIRONMENTAL POLLUTION

Development of a panel of high-throughput reporter-gene assays to detect genotoxicity and oxidative stress

(2013) Sander C. van der Linden et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Oxidative and nitrosative stress and apoptosis in oral mucosa cells after ex vivo exposure to lead and benzo[a]pyrene

(2013) A. Wannhoff et al.   TOXICOLOGY IN VITRO

γH2AX, pChk1, and Wip1 as Potential Markers of Persistent DNA Damage Derived from Dibenzo[a,l]pyrene and PAH-Containing Extracts from Contaminated Soils

(2012) Magdalena Niziolek-Kierecka et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In vivo flow cytometric Pig-a and micronucleus assays: Highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated-dose designs

(2012) Dorothea K. Torous et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Inhalation Cancer Risk Associated with Exposure to Complex Polycyclic Aromatic Hydrocarbon Mixtures in an Electronic Waste and Urban Area in South China

(2012) Jing Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cancer Risk from Incidental Ingestion Exposures to PAHs Associated with Coal-Tar-Sealed Pavement

(2012) E. Spencer Williams et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Glucose-Modulated Mitochondria Adaptation in Tumor Cells: A Focus on ATP Synthase and Inhibitor Factor 1

(2012) Rossana Domenis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dose-Response Assessment of Naphthalene-Induced Genotoxicity and Glutathione Detoxication in Human TK6 Lymphoblasts

(2012) L. Recio et al.   TOXICOLOGICAL SCIENCES

Determination of cytotoxic and genotoxic effects of naphthalene, 1-naphthol and 2-naphthol on human lymphocyte culture

(2012) Mete Kapuci et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Identification of molecular signatures predicting the carcinogenicity of polycyclic aromatic hydrocarbons (PAHs)

(2012) Mi-Kyung Song et al.   TOXICOLOGY LETTERS

Superconductivity of topological matters induced via pressure

(2012) Jun-liang Zhang et al.   Frontiers of Physics

The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance

(2011) Micheline Kirsch-Volders et al.   ARCHIVES OF TOXICOLOGY

Specificity of Human Aldo-Keto Reductases, NAD(P)H:Quinone Oxidoreductase, and Carbonyl Reductases to Redox-Cycle Polycyclic Aromatic Hydrocarbon Diones and 4-Hydroxyequilenin-o-quinone

(2011) Carol A. Shultz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and dna adducts in mutaTMmouse

(2011) Christine L. Lemieux et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Advances in Carcinogenic Metal Toxicity and Potential Molecular Markers

(2011) Preeyaporn Koedrith et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Airborne urban particles (Milan winter-PM2.5) cause mitotic arrest and cell death: Effects on DNA, mitochondria, AhR binding and spindle organization

(2011) Maurizio Gualtieri et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Development and validation of a high-content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells

(2011) Walter M.A. Westerink et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Role of Oxidative Stress in Transformation Induced by Metal Mixture

(2011) Silva-Aguilar Martín et al.   Oxidative Medicine and Cellular Longevity

Assessment of an Association between an Aryl Hydrocarbon Receptor Gene (AHR) Polymorphism and Risk of Male Infertility

(2011) Aihua Gu et al.   TOXICOLOGICAL SCIENCES

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

(2010) M. Fenech et al.   MUTAGENESIS

2-Aminoanthracene, 5-fluorouracil, colchicine, benzo[a]pyrene, cadmium chloride and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster ovary (CHO) cells at Covance Laboratories, Harrogate UK in support of OECD draft Test Guideline 487

(2010) James Whitwell et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo[a]pyrene to form DNA adducts in human cells

(2010) Adeline Tarantini et al.   TOXICOLOGY

Benzo[a]pyrene induces complex H2AX phosphorylation patterns by multiple kinases including ATM, ATR, and DNA-PK

(2010) Chunlan Yan et al.   TOXICOLOGY IN VITRO

Spatial distribution and health risk of heavy metals and polycyclic aromatic hydrocarbons (PAHs) in the water of the Luanhe River Basin, China

(2009) Yongli Li et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Regulation of CYP1A1 by heavy metals and consequences for drug metabolism

(2009) Anwar Anwar-Mohamed et al.   Expert Opinion on Drug Metabolism & Toxicology

Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures

(2009) Adeline Tarantini et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes

(2009) Wei Wei et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo

(2008) Lauren A. Courter et al.   CANCER LETTERS

Possible genotoxic modes of action for naphthalene

(2008) David Brusick et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Antigenotoxicity and antimutagenicity of lycopene in HepG2 cell line evaluated by the comet assay and micronucleus test

(2007) C. Scolastici et al.   TOXICOLOGY IN VITRO

Modulation of TCDD-mediated induction of cytochrome P450 1A1 by mercury, lead, and copper in human HepG2 cell line

(2007) Hesham M. Korashy et al.   TOXICOLOGY IN VITRO

Comparative evaluation of the cytotoxicity sensitivity of six fish cell lines to four heavy metals in vitro

(2007) Fengxia Tan et al.   TOXICOLOGY IN VITRO