Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

(2014) L. McKinley et al.   JOURNAL OF IMMUNOLOGY

The complex relationship between inflammation and lung function in severe asthma

(2014) M L Manni et al.   Mucosal Immunology

Cytokine targets in airway inflammation

(2013) Martijn J Schuijs et al.   CURRENT OPINION IN PHARMACOLOGY

New Insights into the Anti-inflammatory Mechanisms of Glucocorticoids: An Emerging Role for Glucocorticoid-Receptor-Mediated Transactivation

(2013) Sofie Vandevyver et al.   ENDOCRINOLOGY

Comparison of TNF antagonism by etanercept and dexamethasone on airway epithelium and remodeling in an experimental model of asthma

(2013) Ozge Yilmaz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TNF-α–mediated bronchial barrier disruption and regulation by src-family kinase activation

(2013) Michelle A. Hardyman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

(2013) Filip Van Hauwermeiren et al.   JOURNAL OF CLINICAL INVESTIGATION

Poly I:C and respiratory syncytial virus (RSV) inhibit glucocorticoid receptor (GR)-mediated transactivation in lung epithelial, but not monocytic, cell lines

(2013) Jeanette I. Webster Marketon et al.   VIRUS RESEARCH

Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation

(2013) Hiroki Kabata et al.   Nature Communications

Thymic Stromal Lymphopoietin: A Promising Therapeutic Target for Allergic Diseases

(2012) W.L. Wang et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33

(2012) Monique A.M. Willart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints

(2011) Pieter Bogaert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cytokine/anti-cytokine therapy - novel treatments for asthma?

(2011) Philip M Hansbro et al.   BRITISH JOURNAL OF PHARMACOLOGY

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells

(2011) F. Zhang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF

(2011) K-J Choi et al.   GENE THERAPY

Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling

(2011) Jae Youn Cho et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mast cell activation syndrome: A newly recognized disorder with systemic clinical manifestations

(2011) Matthew J. Hamilton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory Stimuli Inhibit Glucocorticoid-Dependent Transactivation in Human Pulmonary Epithelial Cells: Rescue by Long-Acting  2-Adrenoceptor Agonists

(2011) C. F. Rider et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Efficacy and safety of etanercept in moderate-to-severe asthma: a randomised, controlled trial

(2010) S. T. Holgate et al.   EUROPEAN RESPIRATORY JOURNAL

Increased serum IL-17 is an independent risk factor for severe asthma

(2010) Ioana Agache et al.   RESPIRATORY MEDICINE

New therapies for asthma: is there any progress?

(2010) Peter J. Barnes   TRENDS IN PHARMACOLOGICAL SCIENCES

A Randomized, Double-blind, Placebo-controlled Study of Tumor Necrosis Factor-α Blockade in Severe Persistent Asthma

(2009) Sally E. Wenzel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti-tumour necrosis factor   therapy in patients with rheumatoid arthritis results in a significant and long-lasting decrease of concomitant glucocorticoid treatment

(2009) L Naumann et al.   ANNALS OF THE RHEUMATIC DISEASES

Glucocorticoid resistance in inflammatory diseases

(2009) Peter J Barnes et al.   LANCET

Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and COPD

(2009) S Saha et al.   THORAX

Where Asthma and Hypersensitivity Pneumonitis Meet and Differ

(2008) Pieter Bogaert et al.   AMERICAN JOURNAL OF PATHOLOGY

Steroid-Resistant Neutrophilic Inflammation in a Mouse Model of an Acute Exacerbation of Asthma

(2008) Kazuhiro Ito et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

(2008) Gary P Anderson   LANCET

Cytokines Induce an Early Steroid Resistance in Airway Smooth Muscle Cells

(2007) Omar Tliba et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY