Progress in Studies on Rutaecarpine. II.—Synthesis and Structure-Biological Activity Relationships

Quinolone and indole alkaloids from the fruits of Euodia rutaecarpa and their cytotoxicity against two human cancer cell lines

(2015) Nan Zhao et al.   PHYTOCHEMISTRY

A simple approach for the syntheses of rutaecarpine and its analogs

(2015) Li-Na Liang et al.   TETRAHEDRON LETTERS

Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: Synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis

(2014) Imtiaz Khan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Tricyclic Quinazoline Alkaloids: Isolation, Synthesis, Chemical Modification, and Biological Activity

(2014) Kh. M. Shakhidoyatov et al.   CHEMISTRY OF NATURAL COMPOUNDS

Rutaecarpine suppresses atherosclerosis in ApoE−/−mice through upregulating ABCA1 and SR-BI within RCT

(2014) Yanni Xu et al.   JOURNAL OF LIPID RESEARCH

Sequential Sonagashira and Larock Indole Synthesis Reactions in a General Strategy To Prepare Biologically Active β-Carboline-Containing Alkaloids

(2014) Xiaohong Pan et al.   ORGANIC LETTERS

Glyoxylic acid in the reaction of isatoic anhydride with amines: a rapid synthesis of 3-(un)substituted quinazolin-4(3H)-ones leading to rutaecarpine and evodiamine

(2014) K. Raghavendra Rao et al.   TETRAHEDRON LETTERS

A simple heterocyclic fusion reaction and its application for expeditious syntheses of rutaecarpine and its analogs

(2014) Guozheng Huang et al.   TETRAHEDRON LETTERS

Optimization of Rutaecarpine as ABCA1 Up-Regulator for Treating Atherosclerosis

(2014) Yongzhen Li et al.   ACS Medicinal Chemistry Letters

Rutaecarpine Analogues Reduce Lipid Accumulation in Adipocytes via Inhibiting Adipogenesis/Lipogenesis with AMPK Activation and UPR Suppression

(2013) Ying-Chun Chen et al.   ACS Chemical Biology

Selective copper(II) acetate and potassium iodide catalyzed oxidation of aminals to dihydroquinazoline and quinazolinone alkaloids

(2013) Matthew T Richers et al.   Beilstein Journal of Organic Chemistry

Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

(2013) Yan He et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cholinesterase Enzymes Inhibitors from the Leaves of Rauvolfia Reflexa and Their Molecular Docking Study

(2013) Mehran Fadaeinasab et al.   MOLECULES

Facile Access to Ring-Fused Aminals via Direct α-Amination of Secondary Amines with o-Aminobenzaldehydes: Synthesis of Vasicine, Deoxyvasicine, Deoxyvasicinone, Mackinazolinone, and Ruteacarpine

(2013) Daniel Seidel et al.   SYNTHESIS-STUTTGART

New topoisomerases inhibitors: Synthesis of rutaecarpine derivatives and their inhibitory activity against topoisomerases

(2012) Seung Ill Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Total synthesis of ascididemin via anionic cascade ring closure

(2012) Ida Nymann Petersen et al.   CHEMICAL COMMUNICATIONS

2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling

(2012) Zeng Li et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Indoloquinazoline alkaloids fromEuodia rutaecarpaand their cytotoxic activities

(2011) Xin Huang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Recent Advances in the Studies on Luotonins

(2011) Jing Lu Liang et al.   MOLECULES

Bicyclic 1,2,3-Triazolium Ionic Liquids: Synthesis, Characterization, and Application to Rutaecarpine Synthesis

(2011) Ming-Chung Tseng et al.   ORGANIC LETTERS

Multicomponent Assembly Strategies for the Synthesis of Diverse Tetrahydroisoquinoline Scaffolds

(2011) Brett A. Granger et al.   ORGANIC LETTERS

Synthesis and Biological Properties of Benzo-Annulated Rutaecarpines

(2010) Young Hwan Hong et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors

(2010) Bin Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pharmacological Effects of Rutaecarpine as a Cardiovascular Protective Agent

(2010) Sujie Jia et al.   MOLECULES

Total Synthesis of Rutaecarpine and Analogues by Tandem Azido Reductive Cyclization Assisted by Microwave Irradiation

(2010) Ahmed Kamal et al.   SYNLETT

Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice

(2009) Su-Jin Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1)

(2009) Zhuo Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A New and Facile Synthesis of Rutaecarpine Alkaloids

(2009) Chih-Shone Lee et al.   HETEROCYCLES

Progress in the Studies on Rutaecarpine

(2008) Seung Lee et al.   MOLECULES

Synthesis of hybrids between the alkaloids rutaecarpine and luotonins A, B

(2008) Máté Bubenyák et al.   TETRAHEDRON LETTERS

α-Amination of Nitrogen Heterocycles:  Ring-Fused Aminals

(2007) Chen Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-pot reductive-cyclization as key step for the synthesis of rutaecarpine alkaloids

(2007) Chih-Shone Lee et al.   TETRAHEDRON LETTERS