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Progress in the studies on rutaecarpine

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MOLECULES
卷 13, 期 2, 页码 272-300

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MDPI AG
DOI: 10.3390/molecules13020272

关键词

Alkaloid; Rutaceae; rutaecarpine

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Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. Recent progress in the studies on the isolation, synthesis, structure-activity relationship studies, biological activities and metabolism of rutaecarpine are reviewed.

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