标题
Targeting Carbonic Anhydrase IX Activity and Expression
作者
关键词
-
出版物
MOLECULES
Volume 20, Issue 2, Pages 2323-2348
出版商
MDPI AG
发表日期
2015-01-30
DOI
10.3390/molecules20022323
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics
- (2015) Paul C. McDonald et al. Oncotarget
- Prodrug Applications for Targeted Cancer Therapy
- (2014) Irene Giang et al. AAPS Journal
- A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors
- (2014) Nikolaus Krall et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII
- (2014) Aiga Grandane et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay
- (2014) FRANCESCO MARAMPON et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Hypoxia as a biomarker for radioresistant cancer stem cells
- (2014) Claudia Peitzsch et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Structural Insights into Carbonic Anhydrase IX Isoform Specificity of Carbohydrate-Based Sulfamates
- (2014) Janina Moeker et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cyclic Secondary Sulfonamides: Unusually Good Inhibitors of Cancer-Related Carbonic Anhydrase Enzymes
- (2014) Janina Moeker et al. JOURNAL OF MEDICINAL CHEMISTRY
- Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells
- (2014) ZHUO-XIN CHENG et al. ONCOLOGY REPORTS
- Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes
- (2014) Robert Smith et al. PLoS One
- Hypoxia Enhances the Radioresistance of Mouse Mesenchymal Stromal Cells
- (2014) Tara Sugrue et al. STEM CELLS
- A bivalent small molecule-drug conjugate directed against carbonic anhydrase IX can elicit complete tumour regression in mice
- (2014) N. Krall et al. Chemical Science
- The Role of Hypoxia Inducible Factor-1 in Hepatocellular Carcinoma
- (2014) Dongjun Luo et al. Biomed Research International
- Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases
- (2013) Melissa A. Pinard et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including Acetazolamide in human Glioblastoma
- (2013) Harun M. Said et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells
- (2013) Tania Fiaschi et al. CELL CYCLE
- Cell survival and metastasis regulation by Akt signaling in colorectal cancer
- (2013) Ekta Agarwal et al. CELLULAR SIGNALLING
- Carbonic anhydrase inhibitors: an editorial
- (2013) Claudiu T Supuran EXPERT OPINION ON THERAPEUTIC PATENTS
- Therapeutic gene modified cell based cancer vaccines
- (2013) Anna Kozłowska et al. GENE
- Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy
- (2013) Jheel Pandya et al. IMMUNOLOGY AND CELL BIOLOGY
- Multidrug Resistance and Cancer Stem Cells in Neuroblastoma and Hepatoblastoma
- (2013) Anna Alisi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hypoxia promotes radioresistance of CD133-positive Hep-2 human laryngeal squamous carcinoma cells in vitro
- (2013) MAOXIN WANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Interfering Cancer with Polymeric siRNA Nanomedicines
- (2013) Galia Tiram et al. Journal of Biomedical Nanotechnology
- A Prodrug Approach Toward Cancer-Related Carbonic Anhydrase Inhibition
- (2013) Cindy J. Carroux et al. JOURNAL OF MEDICINAL CHEMISTRY
- Wirkmechanismen, klinisches Profil und Stellenwert von Carboanhydrasehemmern in der antiglaukomatösen Therapie
- (2013) M. Eichhorn KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
- Gene Silencing via RNAi and siRNA Quantification in Tumor Tissue Using MEND, a Liposomal siRNA Delivery System
- (2013) Yu Sakurai et al. MOLECULAR THERAPY
- Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference
- (2013) Florie Borel et al. MOLECULAR THERAPY
- Diversifying microRNA sequence and function
- (2013) Stefan L. Ameres et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Suppression of carbonic anhydrase IX leads to aberrant focal adhesion and decreased invasion of tumor cells
- (2013) PETER RADVAK et al. ONCOLOGY REPORTS
- Inhibition of Gastric Cancer Cell Growth In Vivo by Overexpression of Adeno-Associated Virus-Mediated Survivin Mutant C84A
- (2013) Yuan Weng et al. ONCOLOGY RESEARCH
- Inherent and Acquired Resistance to Paclitaxel in Hepatocellular Carcinoma: Molecular Events Involved
- (2013) Avtar Singh Meena et al. PLoS One
- Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs
- (2013) Ludwig Dubois et al. RADIOTHERAPY AND ONCOLOGY
- A pilot study on potential plasma hypoxia markers in the radiotherapy of non-small cell lung cancer
- (2013) C. Ostheimer et al. STRAHLENTHERAPIE UND ONKOLOGIE
- MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines
- (2013) S Grosso et al. Cell Death & Disease
- Hypoxia-Inducible Factors: Mediators of Cancer Progression; Prognostic and Therapeutic Targets in Soft Tissue Sarcomas
- (2013) Navid Sadri et al. Cancers
- Insights towards sulfonamide drug specificity in α-carbonic anhydrases
- (2012) Mayank Aggarwal et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
- (2012) Vincenzo Alterio et al. CHEMICAL REVIEWS
- Structural annotation of human carbonic anhydrases
- (2012) Mayank Aggarwal et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Carbamoylphosphonates Control Tumor Cell Proliferation and Dissemination by Simultaneously Inhibiting Carbonic Anhydrase IX and Matrix Metalloproteinase-2. Toward Nontoxic Chemotherapy Targeting Tumor Microenvironment
- (2012) Reuven Reich et al. JOURNAL OF MEDICINAL CHEMISTRY
- Combinatorial drug therapy for cancer in the post-genomic era
- (2012) Bissan Al-Lazikani et al. NATURE BIOTECHNOLOGY
- Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche
- (2012) F E Lock et al. ONCOGENE
- Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis
- (2011) Su-jong Yu et al. ACTA PHARMACOLOGICA SINICA
- 5- and 6-Membered (thio)lactones are prodrug type carbonic anhydrase inhibitors
- (2011) Fabrizio Carta et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors
- (2011) Kevin Groves et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
- (2011) Y. Lou et al. CANCER RESEARCH
- Development of optimized AAV3 serotype vectors: mechanism of high-efficiency transduction of human liver cancer cells
- (2011) B Cheng et al. GENE THERAPY
- Identification of an animal sucrose transporter
- (2011) H. Meyer et al. JOURNAL OF CELL SCIENCE
- Characterization and inhibition studies of an α-carbonic anhydrase from the endangered sturgeon speciesAcipenser gueldenstaedti
- (2011) Sevgi Kolayli et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Computer Review of ChemDraw Ultra 12.0 ChemDraw Ultra 12.0 . CambridgeSoft , 100 Cambridge Park Drive, Cambridge, MA 02140 . www.cambridgesoft.com . See Web site for full pricing information.
- (2011) Kimberley R. Cousins JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Interfering with pH regulation in tumours as a therapeutic strategy
- (2011) Dario Neri et al. NATURE REVIEWS DRUG DISCOVERY
- Prodrugs--from Serendipity to Rational Design
- (2011) K. M. Huttunen et al. PHARMACOLOGICAL REVIEWS
- High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors
- (2011) Chen Ling et al. Jove-Journal of Visualized Experiments
- Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis
- (2010) Marius I. Ilie et al. INTERNATIONAL JOURNAL OF CANCER
- Sulfonamide Linked Neoglycoconjugates−A New Class of Inhibitors for Cancer-Associated Carbonic Anhydrases
- (2010) Marie Lopez et al. JOURNAL OF MEDICINAL CHEMISTRY
- An animal model of PDH deficiency using AAV8-siRNA vector-mediated knockdown of pyruvate dehydrogenase E1α
- (2010) Carolyn Ojano-Dirain et al. MOLECULAR GENETICS AND METABOLISM
- HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase
- (2010) Ataman Sendoel et al. NATURE
- The structure of adeno-associated virus serotype 3B (AAV-3B): Insights into receptor binding and immune evasion
- (2010) Thomas F. Lerch et al. VIROLOGY
- A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX®) and interferon-alpha-2a in metastatic renal cell carcinoma patients
- (2010) M. Siebels et al. WORLD JOURNAL OF UROLOGY
- Antibody-specific detection of CAIX in breast and prostate cancers
- (2009) Ying Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Short, Strong Hydrogen Bond in the Active Site of Human Carbonic Anhydrase II
- (2009) Balendu Sankara Avvaru et al. BIOCHEMISTRY
- Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target
- (2009) Giuseppina De Simone et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Expression of transmembrane carbonic anhydrases, CAIX and CAXII, in human development
- (2009) Shu-Yuan Liao et al. BMC DEVELOPMENTAL BIOLOGY
- Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
- (2009) V. Alterio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study†
- (2008) Albert A. Barrese et al. BIOCHEMISTRY
- Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes
- (2008) Mika Hilvo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Response to Acidic pH Through OGR1 in a Human Osteoblastic Cell Line
- (2008) Hideaki Tomura et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Therapeutic applications of glycosidic carbonic anhydrase inhibitors
- (2008) Jean-Yves Winum et al. MEDICINAL RESEARCH REVIEWS
- Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
- (2008) Claudiu T. Supuran NATURE REVIEWS DRUG DISCOVERY
- Chronic cellular hypoxia as the prime cause of cancer: What is the de-oxygenating role of adulterated and improper ratios of polyunsaturated fatty acids when incorporated into cell membranes?
- (2007) Brian S. Peskin et al. MEDICAL HYPOTHESES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search