A bivalent small molecule-drug conjugate directed against carbonic anhydrase IX can elicit complete tumour regression in mice
出版年份 2014 全文链接
标题
A bivalent small molecule-drug conjugate directed against carbonic anhydrase IX can elicit complete tumour regression in mice
作者
关键词
-
出版物
Chemical Science
Volume 5, Issue 9, Pages 3640
出版商
Royal Society of Chemistry (RSC)
发表日期
2014-06-20
DOI
10.1039/c4sc00685b
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA)
- (2015) Sangeeta Ray Banerjee et al. Oncotarget
- A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors
- (2014) Nikolaus Krall et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Phase II study of treatment of advanced ovarian cancer with folate-receptor-targeted therapeutic (vintafolide) and companion SPECT-based imaging agent (99mTc-etarfolatide)
- (2014) R. T. Morris et al. ANNALS OF ONCOLOGY
- Synthesis and in Vitro and in Vivo Evaluation of SiFA-Tagged Bombesin and RGD Peptides as Tumor Imaging Probes for Positron Emission Tomography
- (2014) Simon Lindner et al. BIOCONJUGATE CHEMISTRY
- Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity
- (2014) Mariusz Mojzych et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Curative Properties of Noninternalizing Antibody-Drug Conjugates Based on Maytansinoids
- (2014) E. Perrino et al. CANCER RESEARCH
- 4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII
- (2014) Poonam Khloya et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Cyclic Secondary Sulfonamides: Unusually Good Inhibitors of Cancer-Related Carbonic Anhydrase Enzymes
- (2014) Janina Moeker et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small Targeted Cytotoxics: Current State and Promises from DNA-Encoded Chemical Libraries
- (2013) Nikolaus Krall et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Intracellular and Extracellular Carbonic Anhydrases Cooperate Non-enzymatically to Enhance Activity of Monocarboxylate Transporters
- (2013) Michael Klier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Site-specific antibody drug conjugates for cancer therapy
- (2013) Siler Panowski et al. mAbs
- Preclinical Evaluation of a Novel 111In-Labeled Bombesin Homodimer for Improved Imaging of GRPR-Positive Prostate Cancer
- (2013) G. Carlucci et al. MOLECULAR PHARMACEUTICS
- Engineering Folate–Drug Conjugates to Target Cancer: From Chemistry to Clinic
- (2012) Iontcho R. Vlahov et al. BIOCONJUGATE CHEMISTRY
- Antibody-Drug Conjugates for the Treatment of Cancer
- (2012) John A. Flygare et al. Chemical Biology & Drug Design
- Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer
- (2012) Sunil Verma et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche
- (2012) F E Lock et al. ONCOGENE
- A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy
- (2011) Gonçalo J. L. Bernardes et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors
- (2011) Kevin Groves et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
- (2011) Y. Lou et al. CANCER RESEARCH
- Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors
- (2011) Nadia Touisni et al. JOURNAL OF MEDICINAL CHEMISTRY
- Biodistribution and radiation dosimetry of 11C-labelled docetaxel in cancer patients
- (2010) Astrid A. M. van der Veldt et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Improving Tumor Uptake and Pharmacokinetics of64Cu-Labeled Cyclic RGD Peptide Dimers with Gly3and PEG4Linkers
- (2009) Jiyun Shi et al. BIOCONJUGATE CHEMISTRY
- Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours
- (2009) J K J Ahlskog et al. BRITISH JOURNAL OF CANCER
- Prostate-Specific Membrane Antigen Targeted Imaging and Therapy of Prostate Cancer Using a PSMA Inhibitor as a Homing Ligand
- (2009) Sumith A. Kularatne et al. MOLECULAR PHARMACEUTICS
- Carbonic anhydrase IX has chaperone-like functions and is an immunoadjuvant
- (2008) Y. Wang et al. MOLECULAR CANCER THERAPEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation