Penicillin-binding protein 2a of methicillin-resistantStaphylococcus aureus

Regulation of the Expression of the β-Lactam Antibiotic-Resistance Determinants in Methicillin-Resistant Staphylococcus aureus (MRSA)

(2014) Blas Blázquez et al.   BIOCHEMISTRY

Discovery of a New Class of Non-β-lactam Inhibitors of Penicillin-Binding Proteins with Gram-Positive Antibacterial Activity

(2014) Peter I. O’Daniel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of Wall Teichoic Acid Inhibitors as Potential Anti-MRSA β-Lactam Combination Agents

(2013) Hao Wang et al.   CHEMISTRY & BIOLOGY

Methicillin-Resistant Staphylococcus aureus: An Evolving Pathogen

(2013) M. E. Stryjewski et al.   CLINICAL INFECTIOUS DISEASES

A positive interaction between inhibitors of protein synthesis and cefepime in the fight against methicillin-resistant Staphylococcus aureus

(2013) B. Guignard et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Activity of ceftobiprole against methicillin-resistant Staphylococcus aureus strains with reduced susceptibility to daptomycin, linezolid or vancomycin, and strains with defined SCCmec types

(2013) David J. Farrell et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Intrinsic antibiotic resistance: Mechanisms, origins, challenges and solutions

(2013) Georgina Cox et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Prospects for new antibiotics: a molecule-centered perspective

(2013) Christopher T Walsh et al.   JOURNAL OF ANTIBIOTICS

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

(2013) L. H. Otero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allostery and the Monod-Wyman-Changeux Model After 50 Years

(2012) Jean-Pierre Changeux   Annual Review of Biophysics

Characterization of methicillin-resistant Staphylococcus aureus displaying increased MICs of ceftaroline

(2012) R. E. Mendes et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structural Insights into the Anti-methicillin-resistantStaphylococcus aureus(MRSA) Activity of Ceftobiprole

(2012) Andrew L. Lovering et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibacterial drug leads targeting isoprenoid biosynthesis

(2012) W. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to  -Lactam Antibiotics

(2012) C. M. Tan et al.   Science Translational Medicine

Antagonism of Chemical Genetic Interaction Networks Resensitize MRSA to β-Lactam Antibiotics

(2011) Sang Ho Lee et al.   CHEMISTRY & BIOLOGY

Ceftaroline: A Novel Cephalosporin with Activity against Methicillin-resistant Staphylococcus aureus

(2011) L. D. Saravolatz et al.   CLINICAL INFECTIOUS DISEASES

A Computational Evaluation of the Mechanism of Penicillin-Binding Protein-Catalyzed Cross-Linking of the Bacterial Cell Wall

(2011) Qicun Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Affinity of Ceftaroline and Other  -Lactams for Penicillin-Binding Proteins from Staphylococcus aureus and Streptococcus pneumoniae

(2010) K. Kosowska-Shick et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Origin and Molecular Evolution of the Determinant of Methicillin Resistance in Staphylococci

(2010) S. Tsubakishita et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Selection and Characterization of Ceftobiprole-Resistant Methicillin-Resistant Staphylococcus aureus

(2008) R. Banerjee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Co-opting the Cell Wall in Fighting Methicillin-ResistantStaphylococcus aureus: Potent Inhibition of PBP 2a by Two Anti-MRSA β-Lactam Antibiotics

(2008) Adriel Villegas-Estrada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Allosteric regulation and catalysis emerge via a common route

(2008) Nina M Goodey et al.   Nature Chemical Biology