Efficient modification of the myostatin gene in porcine somatic cells and generation of knockout piglets

Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

(2015) M. Crispo et al.   PLoS One

Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs

(2015) Lili Qian et al.   Scientific Reports

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

(2015) Xiaolong Wang et al.   Scientific Reports

Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways

(2014) J. Rodriguez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Efficient Generation of Myostatin (MSTN) Biallelic Mutations in Cattle Using Zinc Finger Nucleases

(2014) Junjie Luo et al.   PLoS One

Genome edited sheep and cattle

(2014) Chris Proudfoot et al.   TRANSGENIC RESEARCH

Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution

(2014) Anna F Gilles et al.   EvoDevo

Advances in genome editing technology and its promising application in evolutionary and ecological studies

(2014) Lei Chen et al.   GigaScience

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

(2013) Mayuko Kurome et al.   BMC BIOTECHNOLOGY

Efficient TALEN construction and evaluation methods for human cell and animal applications

(2013) Tetsushi Sakuma et al.   GENES TO CELLS

Relationships between sensory evaluations of beef tenderness, shear force measurements and consumer characteristics

(2013) Lynn Van Wezemael et al.   MEAT SCIENCE

Highly Efficient Generation of GGTA1 Biallelic Knockout Inbred Mini-Pigs with TALENs

(2013) Jige Xin et al.   PLoS One

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

(2013) W. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs

(2013) Deug-Nam Kwon et al.   Scientific Reports

Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity

(2013) Tetsushi Sakuma et al.   Scientific Reports

Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig

(2012) Anne Richter et al.   BMC BIOTECHNOLOGY

AMPK activation by AICAR inhibits myogenic differentiation and myostatin expression in Cattle

(2012) Masato Miyake et al.   CELL AND TISSUE RESEARCH

Efficient TALEN-mediated gene knockout in livestock

(2012) D. F. Carlson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

(2011) J. Hauschild et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site-directed mutagenesis of the myostatin gene in ovine fetal myoblast cells in vitro

(2011) Yan-ling Zheng et al.   RESEARCH IN VETERINARY SCIENCE

Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases

(2010) Masahito Watanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression

(2009) Alex Hennebry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Porcine Skin-Derived Stem Cells Can Serve as Donor Cells for Nuclear Transfer

(2009) Yanhong Hao et al.   Cloning Stem Cells