Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms

Specification of transplantable astroglial subtypes from human pluripotent stem cells

(2011) Robert Krencik et al.   NATURE BIOTECHNOLOGY

Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease

(2010) Cliona Stack et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy

(2010) D. W. Hampton et al.   JOURNAL OF NEUROSCIENCE

Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity

(2010) F. Leveille et al.   JOURNAL OF NEUROSCIENCE

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

(2010) K. F. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

(2010) R. E. Haskew-Layton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Notch Signaling in Human Embryonic Stem Cell-Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo

(2010) Lodovica Borghese et al.   STEM CELLS

The Nrf2–ARE cytoprotective pathway in astrocytes

(2009) Marcelo R. Vargas et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

(2009) P. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells

(2008) Maria C.N. Marchetto et al.   Cell Stem Cell

Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation

(2008) Francesco Paolo Di Giorgio et al.   Cell Stem Cell

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione

(2008) Francesc X. Soriano et al.   JOURNAL OF NEUROCHEMISTRY

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease

(2008) Angelo C Lepore et al.   NATURE NEUROSCIENCE

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development

(2008) Hayato Naka et al.   NATURE NEUROSCIENCE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON