Pleiotropic drug-resistance attenuated genomic library improves elucidation of drug mechanisms

Laulimalide and peloruside A inhibit mitosis of Saccharomyces cerevisiae by preventing microtubule depolymerisation-dependent steps in chromosome separation and nuclear positioning

(2013) Heather A. Best et al.   Molecular BioSystems

Analyzing Fission Yeast Multidrug Resistance Mechanisms to Develop a Genetically Tractable Model System for Chemical Biology

(2012) Shigehiro A. Kawashima et al.   CHEMISTRY & BIOLOGY

Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae

(2012) Anja Wilmes et al.   GENE

Molecular basis for fungicidal action of neothyonidioside, a triterpene glycoside from the sea cucumber, Australostichopus mollis

(2012) Ploi Yibmantasiri et al.   Molecular BioSystems

Secretory pathway genes assessed by high-throughput microscopy and synthetic genetic array analysis

(2011) Peter W. Bircham et al.   Molecular BioSystems

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

Comparative transcriptome profiling analyses during the lag phase uncover YAP1, PDR1, PDR3, RPN4, and HSF1 as key regulatory genes in genomic adaptation to the lignocellulose derived inhibitor HMF for Saccharomyces cerevisiae

(2010) Menggen Ma et al.   BMC GENOMICS

Combining functional genomics and chemical biology to identify targets of bioactive compounds

(2010) Cheuk Hei Ho et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Microtubule-Stabilizing Drugs from Marine Sponges: Focus on Peloruside A and Zampanolide

(2010) John H. Miller et al.   Marine Drugs

Compensatory activation of the multidrug transporters Pdr5p, Snq2p, and Yor1p by Pdr1p in Saccharomyces cerevisiae

(2008) Anna Kolaczkowska et al.   FEBS LETTERS

RPD3 and ROM2 are required for multidrug resistance in Saccharomyces cerevisiae

(2008) Silvia Borecka-Melkusova et al.   FEMS YEAST RESEARCH

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE