AZD5213: a novel histamine H3 receptor antagonist permitting high daytime and low nocturnal H3 receptor occupancy, a PET study in human subjects

Alterations in the histaminergic system in Alzheimer's disease: a postmortem study

(2012) Ling Shan et al.   NEUROBIOLOGY OF AGING

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [11C]GSK189254 in anesthetized baboon

(2012) Jean Logan et al.   PSYCHOPHARMACOLOGY

The histamine H3 receptor: from discovery to clinical trials with pitolisant

(2011) Jean-Charles Schwartz   BRITISH JOURNAL OF PHARMACOLOGY

Histamine H3 Receptor (H3R) Antagonists and Inverse Agonists in the Treatment of Sleep Disorders

(2011) Meredith Broderick et al.   CURRENT PHARMACEUTICAL DESIGN

Comparison of D2 dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects

(2011) Magdalena Nord et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study

(2011) Ling Shan et al.   NEUROBIOLOGY OF AGING

Histamine receptors in the CNS as targets for therapeutic intervention

(2011) Maria Beatrice Passani et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Functional Increase of Brain Histaminergic Signaling in Huntington's Disease

(2010) Daniel J. van Wamelen et al.   BRAIN PATHOLOGY

Acute Alertness-Promoting Effects of a Novel Histamine Subtype-3 Receptor Inverse Agonist in Healthy Sleep-Deprived Male Volunteers

(2010) R Iannone et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Evaluation of 11C-GSK189254 as a Novel Radioligand for the H3 Receptor in Humans Using PET

(2010) S. Ashworth et al.   JOURNAL OF NUCLEAR MEDICINE

Discovery of Histamine H3 Antagonists for the Treatment of Cognitive Disorders and Alzheimer's Disease

(2010) J. D. Brioni et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Histamine H3 Receptors and Sleep-Wake Regulation

(2010) J.-S. Lin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox−/− mice

(2009) RX Guo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of Sleep-Wake Cycle Modulation

(2009) Eric Murillo-Rodriguez et al.   CNS & Neurological Disorders-Drug Targets

Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT

(2009) Andrea Varrone et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

(2009) Vincent J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

11C-GSK189254: A Selective Radioligand for In Vivo Central Nervous System Imaging of Histamine H3 Receptors by PET

(2009) C. Plisson et al.   JOURNAL OF NUCLEAR MEDICINE

The histamine H3receptor: an attractive target for the treatment of cognitive disorders

(2008) T A Esbenshade et al.   BRITISH JOURNAL OF PHARMACOLOGY

Histamine H3 Antagonists as Wake-Promoting and Pro-Cognitive Agents

(2008) Emily Stocking et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Correlation between ex Vivo Receptor Occupancy and Wake-Promoting Activity of Selective H3 Receptor Antagonists

(2008) S. Le et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pharmacokinetics and time-course of D2 receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients

(2008) AM Catafau et al.   JOURNAL OF PSYCHOPHARMACOLOGY