Beyond the Antioxidant Activity of Dietary Polyphenols in Cancer: the Modulation of Estrogen Receptors (ERs) Signaling

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

(2018) Karen K. L. Chan et al.   Cancer Cell International

Polyphenols in Colorectal Cancer: Current State of Knowledge including Clinical Trials and Molecular Mechanism of Action

(2018) Md Nur Alam et al.   Biomed Research International

Kaempferol, a phytoestrogen, suppressed triclosan-induced epithelial-mesenchymal transition and metastatic-related behaviors of MCF-7 breast cancer cells

(2017) Geum-A Lee et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Phytochemicals Targeting Estrogen Receptors: Beneficial Rather Than Adverse Effects?

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant polyphenols in cancer treatment: Friend, foe or foil?

(2017) Gian Luigi Russo et al.   SEMINARS IN CANCER BIOLOGY

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways

(2017) Shuna Cui et al.   Oncotarget

Compensatory role of Neuroglobin in nervous and non-nervous cancer cells in response to the nutrient deprivation

(2017) Marco Fiocchetti et al.   PLoS One

Naringenin-Mediated ATF3 Expression Contributes to Apoptosis in Human Colon Cancer

(2016) Hun Min Song et al.   Biomolecules & Therapeutics

Estrogen receptor beta as target for colorectal cancer prevention

(2016) Cecilia Williams et al.   CANCER LETTERS

Neuroglobin overexpression induced by the 17β-Estradiol-Estrogen receptor-α Pathway reduces the sensitivity of MCF-7 Breast cancer cell to paclitaxel

(2016) Marco Fiocchetti et al.   IUBMB LIFE

Nuclear and extranuclear-initiated estrogen receptor signaling crosstalk and endocrine resistance in breast cancer

(2016) Eylem Kulkoyluoglu et al.   STEROIDS

Natural Polyphenols for Prevention and Treatment of Cancer

(2016) Yue Zhou et al.   Nutrients

Impact of lower concentrations of phytoestrogens on the effects of estradiol in breast cancer cells

(2015) F-p. Chen et al.   CLIMACTERIC

Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors

(2015) Xujuan Yang et al.   CLINICAL & EXPERIMENTAL METASTASIS

Clathrin Heavy Chain Interacts With Estrogen Receptor α and Modulates 17β-Estradiol Signaling

(2015) Pierangela Totta et al.   MOLECULAR ENDOCRINOLOGY

Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway

(2015) DANDAN SHANG et al.   ONCOLOGY REPORTS

Genistein suppressed epithelial–mesenchymal transition and migration efficacies of BG-1 ovarian cancer cells activated by estrogenic chemicals via estrogen receptor pathway and downregulation of TGF-β signaling pathway

(2015) Ye-Seul Kim et al.   PHYTOMEDICINE

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis

(2015) Xiao Xiao et al.   Oncotarget

Breast Cancer Cell Apoptosis with Phytoestrogens Is Dependent on an Estrogen-Deprived State

(2014) I. E. Obiorah et al.   Cancer Prevention Research

Phytoestrogens and their effects

(2014) Alexander V. Sirotkin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Estrogen receptors alpha (ERα) and beta (ERβ): Subtype-selective ligands and clinical potential

(2014) Ilaria Paterni et al.   STEROIDS

Neuroglobin, a pro-survival player in estrogen receptor α-positive cancer cells

(2014) M Fiocchetti et al.   Cell Death & Disease

Resveratrol regulates the cell viability promoted by 17β-estradiol or bisphenol A via down-regulation of the cross-talk between estrogen receptor α and insulin growth factor-1 receptor in BG-1 ovarian cancer cells

(2013) Nam-Hee Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Antiproliferative activity of daidzein and genistein may be related to ERα/c-erbB-2 expression in human breast cancer cells

(2013) EUN JEONG CHOI et al.   Molecular Medicine Reports

Naringenin (Citrus Flavonone) Induces Growth Inhibition, Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinoma Cells

(2013) Duraikannu Arul et al.   PATHOLOGY & ONCOLOGY RESEARCH

Modulators of estrogen receptor inhibit proliferation and migration of prostate cancer cells

(2013) Margherita Piccolella et al.   PHARMACOLOGICAL RESEARCH

New Concepts, Experimental Approaches, and Dereplication Strategies for the Discovery of Novel Phytoestrogens from Natural Sources

(2013) Thomas Michel et al.   PLANTA MEDICA

Antiproliferative activities of tea and herbal infusions

(2013) Fang Li et al.   Food & Function

Estrogen and Cancer

(2012) Jing Liang et al.   Annual Review of Physiology

Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risks

(2012) Ivonne M. C. M. Rietjens et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Susceptibility of estrogen receptor rapid responses to xenoestrogens: Physiological outcomes

(2012) Maria Marino et al.   STEROIDS

Neuroprotective Effects of 17β-Estradiol Rely on Estrogen Receptor Membrane Initiated Signals

(2012) Marco Fiocchetti et al.   Frontiers in Physiology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Natural polyphenols in cancer therapy

(2011) Miguel Asensi et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Environmental endocrine disruptors: does a sex-related susceptibility exist?

(2011) Pamela Bulzomi   Frontiers in Bioscience-Landmark

The pro-apoptotic effect of quercetin in cancer cell lines requires ERβ-dependent signals

(2011) Pamela Bulzomi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action

(2011) David Vauzour et al.   Nutrients

The Effects of 17β-estradiol in Cancer are Mediated by Estrogen Receptor Signaling at the Plasma Membrane

(2011) Filippo Acconcia et al.   Frontiers in Physiology

Extranuclear Functions of ER Impact Invasive Migration and Metastasis by Breast Cancer Cells

(2010) D. Chakravarty et al.   CANCER RESEARCH

Delphinidin, a dietary anthocyanidin in pigmented fruits and vegetables: A new weapon to blunt prostate cancer growth

(2010) Bilal Bin Hafeez et al.   CELL CYCLE

Estrogen Receptors: Therapies Targeted to Receptor Subtypes

(2010) S Nilsson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Bioavailability of the Polyphenols: Status and Controversies

(2010) Massimo D’Archivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Estrogen Receptor-α Promotes Breast Cancer Cell Motility and Invasion via Focal Adhesion Kinase and N-WASP

(2010) Angel Matias Sanchez et al.   MOLECULAR ENDOCRINOLOGY

Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional Significance

(2010) Laura Bravo   NUTRITION REVIEWS

Plant Polyphenols as Dietary Antioxidants in Human Health and Disease

(2010) Kanti Bhooshan Pandey et al.   Oxidative Medicine and Cellular Longevity

Role of Phytoestrogens in Cancer Therapy

(2010) Mandeep Virk-Baker et al.   PLANTA MEDICA

Estrogen receptor-  activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNF  mediated

(2010) S. J. McPherson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol and chemoprevention

(2009) Shyamal K. Goswami et al.   CANCER LETTERS

Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease

(2009) Ana García-Lafuente et al.   INFLAMMATION RESEARCH

The unfolding stories of GPR30, a new membrane-bound estrogen receptor

(2009) Marcello Maggiolini et al.   JOURNAL OF ENDOCRINOLOGY

Delayed activation of extracellular-signal-regulated kinase 1/2 is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-α-mediated transcription in MCF-7 breast cancer cells

(2009) Huaqing Liu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of diverse dietary phytoestrogens on cell growth, cell cycle and apoptosis in estrogen-receptor-positive breast cancer cells

(2009) Takako Sakamoto et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells

(2009) Li Xu et al.   JNCI-Journal of the National Cancer Institute

Quercetin-induced apoptotic cascade in cancer cells: Antioxidantversusestrogen receptor α-dependent mechanisms

(2009) Paola Galluzzo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Plasma membrane estrogen receptors

(2009) Ellis R. Levin   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Inhibitory effects of genistein on metastasis of human hepatocellular carcinoma

(2009) Yan Gu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

(2008) Eric R. Prossnitz et al.   Annual Review of Physiology

GPR30 Does Not Mediate Estrogenic Responses in Reproductive Organs in Mice

(2008) Christiane Otto et al.   BIOLOGY OF REPRODUCTION

Vegetables and Fruits in Relation to Cancer Risk: Evidence from the Greek EPIC Cohort Study

(2008) V. Benetou et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways

(2008) T. T. Onder et al.   CANCER RESEARCH

The Nutritional Flavanone Naringenin Triggers Antiestrogenic Effects by Regulating Estrogen Receptor α-Palmitoylation

(2008) Paola Galluzzo et al.   ENDOCRINOLOGY

Phytoestrogens and Breast Cancer Prevention: Possible Mechanisms of Action

(2008) Sarah M. Mense et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Regulation of cellular signals from nutritional molecules: a specific role for phytochemicals, beyond antioxidant activity

(2008) F VIRGILI et al.   FREE RADICAL BIOLOGY AND MEDICINE

Estrogen and its receptors in cancer

(2008) George G Chen et al.   MEDICINAL RESEARCH REVIEWS

Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells

(2008) Jung-Mi Yun et al.   MOLECULAR CARCINOGENESIS

Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways

(2008) Sonia Ramos   MOLECULAR NUTRITION & FOOD RESEARCH

Extra-Nuclear Signalling of Estrogen Receptor to Breast Cancer Cytoskeletal Remodelling, Migration and Invasion

(2008) Maria Silvia Giretti et al.   PLoS One

Phosphorylation of Activation Function-1 Regulates Proteasome-Dependent Nuclear Mobility and E6-Associated Protein Ubiquitin Ligase Recruitment to the Estrogen Receptor β

(2007) Nathalie Picard et al.   MOLECULAR ENDOCRINOLOGY