Glucosylceramide synthase promotes Bcl-2 expression via the ERK signaling pathway in the K562/A02 leukemia drug-resistant cell line

The Tricyclodecan-9-yl-xanthogenate D609 Triggers Ceramide Increase and Enhances FasL-Induced Caspase-Dependent and -Independent Cell Death in T Lymphocytes

(2012) Delphine Milhas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

(2011) Inthrani R. Indran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer

(2011) Yixing Jiang et al.   CANCER BIOLOGY & THERAPY

The effect of glucosylceramide synthase on P-glycoprotein function in K562/AO2 leukemia drug-resistance cell line

(2011) Yang-Yang Zhang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Upregulation of RhoB via c-Jun N-terminal kinase signaling induces apoptosis of the human gastric carcinoma NUGC-3 cells treated with NSC12618

(2010) Bo-Kyung Kim et al.   CARCINOGENESIS

Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK

(2010) Alina Felicia Nica et al.   CELL CYCLE

Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

(2010) Suriyan Ponnusamy et al.   Future Oncology

Potential Mechanisms Involved in Ceramide-induced Apoptosis in Human Colon Cancer HT29 Cells

(2009) Jing WANG et al.   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

GCS induces multidrug resistance by regulating apoptosis-related genes in K562/AO2 cell line

(2009) Yan Liu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A New Mixed-Backbone Oligonucleotide against Glucosylceramide Synthase Sensitizes Multidrug-Resistant Tumors to Apoptosis

(2009) Gauri A. Patwardhan et al.   PLoS One

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

(2008) C.-L. Chen et al.   BLOOD

A role for ceramide in driving cancer cell resistance to doxorubicin

(2008) Yong-Yu Liu et al.   FASEB JOURNAL

Overexpression of glucosylceramide synthase in associated with multidrug resistance of leukemia cells

(2007) Ping Xie et al.   LEUKEMIA RESEARCH