Pharmacokinetics, pharmacodynamics and efficacy on pediatric tumors of the glioma radiosensitizer KU60019

ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation

(2013) L. Biddlestone-Thorpe et al.   CLINICAL CANCER RESEARCH

Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma

(2013) Carlos Rodrigo Gil del Alcazar et al.   CLINICAL CANCER RESEARCH

Predictability, efficacy and safety of radiosensitization of glioblastoma-initiating cells by the ATM inhibitor KU-60019

(2013) Donatella Vecchio et al.   INTERNATIONAL JOURNAL OF CANCER

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Preclinical Evaluation of a Novel ATM Inhibitor, KU59403, In Vitro and In Vivo in p53 Functional and Dysfunctional Models of Human Cancer

(2013) M. A. Batey et al.   MOLECULAR CANCER THERAPEUTICS

Current status of local therapy in malignant gliomas — A clinical review of three selected approaches

(2013) Tareq A Juratli et al.   PHARMACOLOGY & THERAPEUTICS

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

Analysis of NADP+-dependent isocitrate dehydrogenase-1/2 gene mutations in pediatric brain tumors: report of a secondary anaplastic astrocytoma carrying the IDH1 mutation

(2012) Samantha Mascelli et al.   JOURNAL OF NEURO-ONCOLOGY

Paediatric and adult malignant glioma: close relatives or distant cousins?

(2012) Chris Jones et al.   Nature Reviews Clinical Oncology

Prospective isolation of clonogenic mantle cell lymphoma-initiating cells

(2010) Zheng Chen et al.   Stem Cell Research

Awaking stem cells from dormancy: growing old and fighting cancer

(2009) Andrea Viale et al.   EMBO Molecular Medicine

Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures

(2009) M. Ropolo et al.   MOLECULAR CANCER RESEARCH

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

(2009) Andrea Viale et al.   NATURE