Article
Oncology
Xu Guan, Ran Wei, Runkun Yang, Zhao Lu, Enrui Liu, Zhixun Zhao, Haipeng Chen, Ming Yang, Zheng Liu, Zheng Jiang, Xishan Wang
Summary: The study found that rectal cancer patients who received radiation therapy were more likely to develop secondary bladder cancer, emphasizing the importance of increased surveillance for these patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Erin E. Gabriel, Elizabeth Arkema, Michael C. Sachs
Summary: This paper illustrates the use of pseudo-observation based regression for estimating risks of time-to-event outcomes in epidemiological studies. The method allows for estimation of relative and absolute risks at specific times without the need for secondary calculations or standardization. The results demonstrate the adjusted mortality risk differences and risk ratios by age, as well as at different years of follow-up.
ANNALS OF EPIDEMIOLOGY
(2022)
Article
Oncology
Aivara Urbute, Freja L. Sand, Federica Belmonte, Lene H. Iversen, Christian Munk, Susanne K. Kjaer
Summary: The incidence of rectal cancer in Denmark has shown a fluctuating trend from 1978 to 2018, with a decrease in all age groups and both sexes initially but an increase since 1998, more significantly in men. Mortality decreased over time with adjustments, and the improvement in relative survival was more pronounced in men, leading to virtually identical survival rates for men and women in recent years.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2022)
Article
Public, Environmental & Occupational Health
Andri Wilberg Orrason, Hans Garmo, Johan Styrke, Paul W. Dickman, Par Stattin
Summary: Net survival, measured in different frameworks, such as relative survival and cause-specific survival, was compared in men with prostate cancer. The study found biases in estimates of survival rates for different age groups and risk categories, emphasizing the importance of evaluating underlying assumptions for each method.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Medicine, General & Internal
Rossella Reddavid, Silvia Sofia, Lucia Puca, Jacopo Moro, Simona Ceraolo, Rosa Jimenez-Rodriguez, Maurizio Degiuli
Summary: This meta-analysis examined the feasibility and safety of robotic surgery for elderly patients (>70 years old) undergoing curative treatment for rectal cancer. The study found that elderly patients can undergo robotic resection with similar surgical quality and outcomes as young patients, without increasing postoperative mortality and morbidity. Therefore, robotic surgery is a viable option for elderly patients with rectal cancer.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Chengshi Wang, Tao He, Zhu Wang, Dan Zheng, Chaoyong Shen
Summary: Breast cancer patients have an increased risk of cardiovascular disease mortality, especially within the first month after diagnosis, especially for young patients or those with aggressive tumor stages.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Maria Bisgaard Bengtsen, Dora Kormendine Farkas, Michael Borre, Henrik Toft Sorensen, Mette Norgaard
Summary: The study found that after acute urinary retention, the absolute risk of prostate cancer was 5.1% at three months, 6.7% at one year, and 8.5% at five years. For most of the studied cancers, the excess risk was most significant within three months.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Oncology
Yang Su, Da Shuai Yang, Yan Qi Li, JichaoQ Qin, Lu Liu
Summary: The purpose of this study was to develop a novel and practical nomogram and risk stratification system to accurately predict cancer-specific survival (CSS) of early-onset locally advanced rectal cancer (EO-LARC) patients. Through analysis of data from 2440 EO-LARC patients, seven variables were identified for the construction of the nomogram and risk classification system. These tools can effectively predict patient prognosis and be used for individualized treatment and improved clinical decision-making.
FRONTIERS IN ONCOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Soren Rattenborg, Soeren Moeller, Erik Frostberg, Hans B. Rahr
Summary: The purpose of this study was to examine the variation in the prevalence of patient-related risk factors for adverse outcomes of colorectal cancer treatment between hospitals in Denmark. A national cohort of 44,471 CRC patients registered in the Danish Colorectal Cancer Group database from 2009 to 2018 was included. Patient-related risk factors were collected from national Danish registers, and prediction models were used to examine the impact on outcomes and variations between hospitals.
CLINICAL EPIDEMIOLOGY
(2023)
Article
Biology
Cheng-Hong Yang, Wen -Ching Chen, Jin-Bor Chen, Hsiu-Chen Huang, Li-Yeh Chuang
Summary: This study proposed an advanced analytic approach, called Fuzzy-based RNNCoxPH, for detecting missense variants associated with high-risk of all-cause mortality in rectum adenocarcinoma. The Fuzzy-based RNNCoxPH model exhibits higher efficacy in identifying and classifying the missense variants related to mortality risk in rectum adenocarcinoma compared to other test methods.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Multidisciplinary Sciences
Nader Al-Dewik, Muthanna Samara, Salma Younes, Rana Al-jurf, Gheyath Nasrallah, Sawsan Al-Obaidly, Husam Salama, Tawa Olukade, Sara Hammuda, Neil Marlow, Mohamed Ismail, Taghreed Abu Nada, M. Walid Qoronfleh, Binny Thomas, Ghassan Abdoh, Palli Valapila Abdulrouf, Thomas Farrell, Mai Al Qubaisi, Hilal Al Rifai
Summary: This study aimed to assess the incidence, risk factors, and outcomes of major congenital anomalies (CAs) in Qatar. The study found that the incidence of any CA among live births in Qatar was 1.3%, with cardiovascular system (CVS) anomalies being the most common. Multiple pregnancies, parity, and maternal BMI were associated with specific CAs. CAs were significantly associated with high rates of caesarean deliveries, low Apgar scores, in-hospital mortality, and neonatal intensive care unit admission.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Ausvydas Patasius, Giedre Smailyte
Summary: This study in Lithuania on prostate cancer screening revealed that before screening, patients who were not screened had higher all-cause mortality risk, while those who were screened had similar all-cause mortality risk to the general population. Additionally, screened patients with localized stage of disease had lower all-cause mortality risk compared to the general population.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Oncology
Niamh McKigney, Fergus Houston, Ellen Ross, Galina Velikova, Julia Brown, Deena Pravin Harji
Summary: This study aimed to identify the patient-reported outcome measures (PROMs) currently being reported in locally recurrent rectal cancer (LRRC) and to appraise the methodological quality of studies using these measures. Thirty-five studies including 1914 patients with LRRC were identified. None of the PROMs have been validated for use in this cohort of patients.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Petrus Bostrom, Daniel Kverneng Hultberg, Jenny Haggstrom, Markku M. Haapamaki, Peter Matthiessen, Jorgen Rutegard, Martin Rutegard
Summary: This study found no association between the level of tie in rectal cancer surgery and oncological outcomes. High tie surgery increased total lymph node harvest but did not impact the number of positive nodes.
Article
Gastroenterology & Hepatology
Frederikke Schonfeldt Troelsen, Henrik Toft Sorensen, Lars Pedersen, Rune Erichsen
Summary: A cohort study comparing IBD and non-IBD patients undergoing colonoscopy found that although PCCRCs accounted for a substantial proportion of all IBD-related CRCs, IBD patients had a low CIP of PCCRC, while the 3-year PCCRC rates were significantly higher for IBD patients compared to non-IBD patients.
Article
Gastroenterology & Hepatology
Marzieh Araghi, Melina Arnold, Mark J. Rutherford, Marianne Gronlie Guren, Citadel J. Cabasag, Aude Bardot, Jacques Ferlay, Hanna Tervonen, Lorraine Shack, Ryan R. Woods, Nathalie Saint-Jacques, Prithwish De, Carol McClure, Gerda Engholm, Anna T. Gavin, Eileen Morgan, Paul M. Walsh, Christopher Jackson, Geoff Porter, Bjorn Moller, Oliver Bucher, Michael Eden, Dianne L. O'Connell, Freddie Bray, Isabelle Soerjomataram
Summary: The study provides the most recent estimates of colon and rectal cancer survival in seven high-income countries, showing variations in survival rates based on stage at diagnosis, age, and country.
Article
Gastroenterology & Hepatology
Eileen Morgan, Isabelle Soerjomataram, Anna T. Gavin, Mark J. Rutherford, Piers Gatenby, Aude Bardot, Jacques Ferlay, Oliver Bucher, Prithwish De, Gerda Engholm, Christopher Jackson, Serena Kozie, Alana Little, Bjorn Moller, Lorraine Shack, Hanna Tervonen, Vicky Thursfield, Sally Vernon, Paul M. Walsh, Ryan R. Woods, Christian Finley, Neil Merrett, Dianne L. O'Connell, John Reynolds, Freddie Bray, Melina Arnold
Summary: The survival of esophageal cancer has significantly improved over the past 20 years in participating countries, especially for adenocarcinoma, younger age groups, and the first year after diagnosis. Australia and Ireland consistently showed higher survival rates. However, further advancements in early detection and treatment are needed for specific groups and patients with squamous cell carcinoma.
Article
Oncology
Therese M. -L. Andersson, Mark J. Rutherford, Tor Age Myklebust, Bjorn Moller, Isabelle Soerjomataram, Melina Arnold, Freddie Bray, D. Max Parkin, Peter Sasieni, Oliver Bucher, Prithwish De, Gerda Engholm, Anna Gavin, Alana Little, Geoff Porter, Agnihotram V. Ramanakumar, Nathalie Saint-Jacques, Paul M. Walsh, Ryan R. Woods, Paul C. Lambert
Summary: The ICBP SURVMARK-2 study aims to quantify and explore the reasons behind survival differences across high-income countries using population-based cancer registry data. Differences in cancer survival estimates between countries may be partly explained by variations in registration practice, completeness, and data sources quality.
BRITISH JOURNAL OF CANCER
(2021)
Article
Oncology
Therese M-L Andersson, Tor Age Myklebust, Mark J. Rutherford, Bjorn Moller, Isabelle Soerjomataram, Melina Arnold, Freddie Bray, D. Max Parkin, Peter Sasieni, Oliver Bucher, Prithwish De, Gerda Engholm, Anna Gavin, Alana Little, Geoff Porter, Agnihotram Ramanakumar, Nathalie Saint-Jacques, Paul M. Walsh, Ryan R. Woods, Paul C. Lambert
Summary: Population-based cancer registries utilize death certificates to include Death Certificate Initiated (DCI) cases for estimating cancer incidence, but its inclusion could lead to biased estimates of cancer survival. Excluding DCI cases may result in overestimation of survival estimates, considering the differences between DCI cases and missed cases.
CANCER EPIDEMIOLOGY
(2021)
Article
Oncology
Eileen Morgan, Melina Arnold, Mark J. Rutherford, Aude Bardot, Jacques Ferlay, Prithwish De, Gerda Engholm, Christopher Jackson, Alana Little, Nathalie Saint-Jacques, Paul Walsh, Ryan R. Woods, Dianne L. O'Connell, Freddie Bray, D. Max Parkin, Isabelle Soerjomataram
Summary: Research has shown variations in lung cancer survival rates among different countries, partially attributable to differences in the distribution of unspecified histology cases. International differences in SCLC and NSCLC survival rates are only partially attributable to differences in the distribution of unspecified histology, with other factors such as underlying risk factors, stage, comorbidity, and care management also playing significant roles.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Mark J. Rutherford, Melina Arnold, Aude Bardot, Jacques Ferlay, Prithwish De, Hannah Tervonen, Alana Little, Oliver Bucher, Nathalie St Jacques, Anna Gavin, Gerda Engholm, Bjorn Moller, Dianne L. O'Connell, Neil Merrett, Donald Maxwell Parkin, Freddie Bray, Isabelle Soerjomataram
Summary: International comparison of liver cancer survival faces challenges due to differences in morphological verification standards and coding practices. This article presents comparisons of liver cancer survival across ICBP jurisdictions and highlights the poor survival rates in all countries. Australia has the highest survival rates, especially for morphologically verified tumors.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Respiratory System
Marzieh Araghi, Miranda Fidler-Benaoudia, Melina Arnold, Mark Rutherford, Aude Bardot, Jacques Ferlay, Oliver Bucher, Prithwish De, Gerda Engholm, Anna Gavin, Serena Kozie, Alana Little, Bjorn Moller, Nathalie St Jacques, Hanna Tervonen, Paul Walsh, Ryan Woods, Dianne L. O'Connell, David Baldwin, Mark Elwood, Sabine Siesling, Freddie Bray, Isabelle Soerjomataram
Summary: Lung cancer prognosis varies internationally, with Canada and Norway showing higher survival rates and the UK, New Zealand, and Ireland showing lower rates. Differences in survival were observed based on sex, histological subtype, and stage at diagnosis, with potential factors including quality of treatment, healthcare system factors, and comorbid conditions. Additionally, variations in data collection practices and histological verification may contribute to the observed discrepancies in survival rates across different jurisdictions.
Article
Oncology
Therese M. -L. Andersson, Mark J. Rutherford, Tor Age Myklebust, Bjorn Moller, Melina Arnold, Isabelle Soerjomataram, Freddie Bray, Hazem Abd Elkader, Gerda Engholm, Dyfed Huws, Alana Little, Lorraine Shack, Paul M. Walsh, Ryan R. Woods, D. Maxwell Parkin, Paul C. Lambert
Summary: The study found that, except in Ireland, there were few long-term survivors in the early years of the ICBP SURVMARK-2 project. This finding is important for accurately estimating cancer patient survival.
CANCER EPIDEMIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Melina Arnold, Eileen Morgan, Aude Bardot, Mark J. Rutherford, Jacques Ferlay, Alana Little, Bjorn Moller, Oliver Bucher, Prithwish De, Ryan R. Woods, Nathalie Saint-Jacques, Anna T. Gavin, Gerda Engholm, Michael P. Achiam, Geoff Porter, Paul M. Walsh, Sally Vernon, Serena Kozie, Agnihotram Ramanakumar, Charlotte Lynch, Samantha Harrison, Neil Merrett, Dianne L. O'Connell, Tom Mala, Mark Elwood, John Zalcberg, Dyfed W. Huws, David Ransom, Freddie Bray, Isabelle Soerjomataram
Summary: This study provides the first international comparison of oesophageal and gastric cancer survival by stage at diagnosis and histological subtype across high-income countries with similar access to healthcare. The results show that survival from these cancers varies across countries, particularly for localised disease, and differences in treatment, cancer registration practice, and staging methods may impact these comparisons.
Article
Oncology
Ines Mesa-Eguiagaray, Sarah H. Wild, Sheila M. Bird, Linda J. Williams, David H. Brewster, Peter S. Hall, Jonine D. Figueroa
Summary: Women from socio-economically deprived areas are less likely to develop and survive breast cancer. In Scotland, the incidence and survival rates of breast cancer are associated with tumor subtypes and mode of detection. Deprivation is associated with higher mortality rates for estrogen receptor positive and HER2-enriched breast cancer.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Oncology
Usha Menon, David Weller, Alina Zalounina Falborg, Henry Jensen, John Butler, Andriana Barisic, Anne Kari Knudsen, Rebecca J. Bergin, David H. Brewster, Victoria Cairnduff, Evangelia Ourania Fourkala, Anna T. Gavin, Eva Grunfeld, Elizabeth Harland, Jatinderpal Kalsi, Rebecca-Jane Law, Yulan Lin, Donna Turner, Richard D. Neal, Victoria White, Samantha Harrison, Irene Reguilon, Charlotte Lynch, Peter Vedsted
Summary: The international comparison study on ovarian cancer diagnosis routes and intervals reveals variations among different jurisdictions. This study presents an opportunity to improve the key intervals in diagnosis and treatment of ovarian cancer.
BRITISH JOURNAL OF CANCER
(2022)
Article
Oncology
Frida E. Lundberg, Helgi Birgisson, Tom B. Johannesen, Gerda Engholm, Anni Virtanen, David Pettersson, Elinborg J. Olafsdottir, Mats Lambe, Paul C. Lambert, Lina S. Morch, Anna L. Johansson, Therese M-L Andersson
Summary: The survival of patients with colon and rectal cancer has improved in all Nordic countries over the past decades. The study shows that the survival rate has improved for both men and women in all age groups. The largest improvement was observed in Danish men and women with rectal cancer. The probability of death and life-years lost varied across countries.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Oncology
Frida E. Lundberg, Niels Kroman, Mats Lambe, Therese M. -L. Andersson, Gerda Engholm, Tom Borge Johannesen, Anni Virtanen, David Pettersson, Elinborg J. Olafsdottir, Helgi Birgisson, Paul C. Lambert, Lina Steinrud Morch, Anna L. V. Johansson
Summary: The survival rates for Nordic women with breast cancer improved from 1990 to 2016 in all age groups, with larger country variations among older women where survival rates were lower. Women over the age of 70 have not seen the same level of survival improvement as younger women.
Article
Medicine, General & Internal
Peter Vedsted, David Weller, Alina Zalounina Falborg, Henry Jensen, Jatinderpal Kalsi, David Brewster, Yulan Lin, Anna Gavin, Andriana Barisic, Eva Grunfeld, Mats Lambe, Martin Malmberg, Donna Turner, Elizabeth Harland, Breann Hawryluk, Rebecca-Jane Law, Richard D. Neal, Victoria White, Rebecca Bergin, Samantha Harrison, Usha Menon
Summary: This study explores the differences in breast cancer diagnostic pathways among multiple countries, and finds that some jurisdictions have developed more effective strategies in optimizing pathways and reducing time intervals. Targeted awareness interventions could also facilitate more timely diagnosis of breast cancer.
Article
Oncology
Hans Henrik Storm, Siri Laronningen, Freddie Bray
Summary: The KIN project provided timely cancer statistics for cancer control planning in the Nordic countries, and the development of NORDCAN project reduced investment costs and increased scientific value.