Article
Oncology
Eduardo A. Vega, Timothy E. Newhook, Sebastian Mellado, Andrea Ruzzenente, Masayuki Okuno, Mario De Bellis, Elena Panettieri, M. Usman Ahmad, Ignacio Merlo, Jesus Rojas, Agostino M. De Rose, Hiroto Nishino, Andrew J. Sinnamon, Matteo Donadon, Marit S. Hauger, Oscar A. Guevara, Cesar Munoz, Jason W. Denbo, Yun Shin Chun, Hop Tran S. Cao, Rodrigo Sanchez Claria, Ching-Wei D. Tzeng, Xabier De Aretxabala, Marcelo Vivanco, Kristoffer W. Brudvik, Satoru Seo, Juan Pekolj, George A. Poultsides, Guido Torzilli, Felice Giuliante, Daniel A. Anaya, Alfredo Guglielmi, Eduardo Vinuela, Jean-Nicolas Vauthey
Summary: This study aimed to define benchmark values for gallbladder cancer surgery and assess surgical quality through comparisons among an international population. The results showed that 20% of patients in the benchmark group experienced postoperative complications, with a median hospital stay of 6 days.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Dong Wook Shin, Jaeman Bae, Johyun Ha, Kyu-Won Jung
Summary: The study presents 5-year relative conditional survival probabilities for ovarian cancer patients from 1997-2016. The results showed that the conditional survival rates increased with each year survived, but even after 5 years, the excess mortality did not reach 'no excess mortality' level. Patients with poorer initial prognoses showed the largest improvements in conditional survival rates.
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Ellen Nolte, Melanie Morris, Susan Landon, Martin McKee, Maureen Seguin, John Butler, Mark Lawler
Summary: This study examines the relationship between cancer policy consistency and cancer survival rates, finding a positive correlation. The findings provide guidance for policymakers in improving cancer services and outcomes.
Article
Medicine, General & Internal
Peter Vedsted, David Weller, Alina Zalounina Falborg, Henry Jensen, Jatinderpal Kalsi, David Brewster, Yulan Lin, Anna Gavin, Andriana Barisic, Eva Grunfeld, Mats Lambe, Martin Malmberg, Donna Turner, Elizabeth Harland, Breann Hawryluk, Rebecca-Jane Law, Richard D. Neal, Victoria White, Rebecca Bergin, Samantha Harrison, Usha Menon
Summary: This study explores the differences in breast cancer diagnostic pathways among multiple countries, and finds that some jurisdictions have developed more effective strategies in optimizing pathways and reducing time intervals. Targeted awareness interventions could also facilitate more timely diagnosis of breast cancer.
Article
Oncology
Dong Wook Shin, Jaeman Bae, Johyun Ha, Kyu Won Jung
Summary: This study investigated conditional relative survival (CRS) among cervical cancer patients and found that patients with poorer initial survival estimates showed the largest increases in CRS over time. The probability of surviving an additional 5 years conditioned on time already survived increased gradually, providing patients with more information for follow-up care and future life decisions.
JOURNAL OF GYNECOLOGIC ONCOLOGY
(2021)
Article
Multidisciplinary Sciences
Silvia De Rosa, Nicolo Sella, Emanuele Rezoagli, Giulia Lorenzoni, Dario Gregori, Giacomo Bellani, Giuseppe Foti, Tommaso Pettenuzzo, Fabio Baratto, Giorgio Fullin, Francesco Papaccio, Mario Peta, Daniele Poole, Fabio Toffoletto, Salvatore Maurizio Maggiore, Paolo Navalesi
Summary: This study aims to describe the real clinical practice of using PP in COVID-19 patients during the pandemic and identify subpopulations that may benefit from this treatment. The registry will provide valuable information to improve daily clinical practice.
Article
Oncology
Dong Wook Shin, Kyu-Won Jung, Johyun Ha, Jaeman Bae
Summary: The objective of this study was to estimate the 5-year conditional relative survival rates of endometrial cancer in Korea, taking into account the time already survived. The study found that the survival rates improved with increased time elapsed from diagnosis. Older patients, those with non-endometrioid histology, and those with more advanced disease showed the greatest improvements in survival rates.
JOURNAL OF GYNECOLOGIC ONCOLOGY
(2022)
Article
Geriatrics & Gerontology
Takehito Shukuya, Kazuhisa Takahashi, Yasushi Shintani, Keita Miura, Ikuo Sekine, Koichi Takayama, Akira Inoue, Isamu Okamoto, Katsuyuki Kiura, Tomoya Kawaguchi, Nobuyuki Yamamoto, Etsuo Miyaoka, Ichiro Yoshino, Hiroshi Date
Summary: This study examined the epidemiology, risk factors, and impact of cancer cachexia on chemotherapy response rate and prognosis in lung cancer patients. Cancer cachexia significantly affects a patient's quality of life and prognosis. Understanding these factors related to cancer cachexia is crucial for overcoming it in lung cancer patients.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Oncology
Jordan Santucci, Mark Tacey, Benjamin Thomson, Michael Michael, Rachel Wong, Julia Shapiro, Ross Jennens, Kate Clarke, Sharon Pattison, Matthew Burge, Rob Zielinski, Mehrdad Nikfarjam, Sumitra Ananda, Lara Lipton, Peter Gibbs, Belinda Lee
Summary: There was no significant difference in overall survival between first-line chemotherapy regimens of Gemcitabine/Nab-Paclitaxel and FOLFIRINOX in advanced pancreatic ductal adenocarcinoma (PDAC). However, FOLFIRINOX was associated with delayed disease progression.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Multidisciplinary Sciences
Meifang Li, Xun Shi, Jiang Gui, Chao Song, Angeline S. Andrew, Erik P. Pioro, Elijah W. Stommel, Maeve Tischbein, Walter G. Bradley
Summary: A new method was developed to estimate the number of ALS cases missed by the disease registry in Ohio, which improved the correlation between case counts and mortality counts in target counties.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Daisuke Miyamori, Tsukasa Kamitani, Shuhei Yoshida, Yuya Shigenobu, Kotaro Ikeda, Yuka Kikuchi, Saori Kashima, Yosuke Yamamoto
Summary: This study found an increased colorectal cancer mortality during the COVID-19 pandemic period, indicating a continuous impact of the pandemic on known and unknown risk factors for colorectal cancer. Further research is needed to mitigate the adverse effects on patient outcomes.
Article
Oncology
Francesco Giusti, Carmen Martos, Raquel Negrao Carvalho, Liesbet Van Eycken, Otto Visser, Manola Bettio
Summary: Population-based Cancer Registries (PBCRs) play a crucial role in collecting high-quality data for monitoring cancer burden, planning cancer control activities, and conducting research. This article evaluates the quality of PBCRs data collected in a specific data call in 2015.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Eileen Morgan, Melina Arnold, Mark J. Rutherford, Aude Bardot, Jacques Ferlay, Prithwish De, Gerda Engholm, Christopher Jackson, Alana Little, Nathalie Saint-Jacques, Paul Walsh, Ryan R. Woods, Dianne L. O'Connell, Freddie Bray, D. Max Parkin, Isabelle Soerjomataram
Summary: Research has shown variations in lung cancer survival rates among different countries, partially attributable to differences in the distribution of unspecified histology cases. International differences in SCLC and NSCLC survival rates are only partially attributable to differences in the distribution of unspecified histology, with other factors such as underlying risk factors, stage, comorbidity, and care management also playing significant roles.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Anton Barchuk, Rustam Tursun-Zade, Ekaterina Nazarova, Yuri Komarov, Ekaterina Tyurina, Yulia Tumanova, Alexey Belyaev, Ariana Znaor
Summary: This study aimed to assess the completeness of the data from ten population-based cancer registries in Northwest Russia.
Article
Oncology
Eun-Gyeong Lee, Jiwon Lim, Hyeong In Ha, Myong Cheol Lim, Yoon Jung Chang, Young-Joo Won, So-Youn Jung
Summary: This study in Korea found that the incidence of second primary breast cancer in ovarian cancer patients is 1.27 times higher than in healthy individuals. Survival outcomes for SPBC were poorer than for PBC, especially in older patients and those with advanced stage cancer. Active screening for breast cancer is necessary for ovarian cancer patients to improve prognosis.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Oleg Blyuss, Amanda Dibden, Nathalie J. Massat, Dharmishta Parmar, Jack Cuzick, Stephen W. Duffy, Peter Sasieni
Summary: This study aimed to estimate the effect of the NHS Breast Screening Programme in England on breast cancer incidence and overdiagnosis. The results showed that the programme confers at worst modest levels of overdiagnosis.
Article
Public, Environmental & Occupational Health
Ryan R. Woods, Erich Kliewer, Kimberlyn M. McGrail, John J. Spinelli
Summary: Breast cancer screening utilization and stage distributions vary between immigrant and non-immigrant populations. Indian and Chinese immigrants have lower breast cancer incidence rates, but Indian immigrants have a higher frequency of later-stage diagnosis, while Chinese immigrants have a lower frequency. Filipino immigrants have similar rates and stage at diagnosis compared to non-immigrants. These findings emphasize the importance of monitoring cancer among immigrant and non-immigrant populations.
JOURNAL OF IMMIGRANT AND MINORITY HEALTH
(2023)
Article
Oncology
Fabio Girardi, Veronica Di Carlo, Charles Stiller, Gemma Gatta, Ryan R. Woods, Otto Visser, Brigitte Lacour, Thomas C. Tucker, Michel P. Coleman, Claudia Allemani
Summary: This study provides comprehensive data on global trends in population-based survival for childhood brain tumors. The researchers used a revised version of the International Classification of Childhood Cancer and estimated survival rates for different histology groups. The findings have important implications for public health.
Article
Dermatology
Isabelle Krakowski, Henrike Habel, Kari Nielsen, Christian Ingvar, Therese M. L. Andersson, Ada Girnita, Karin E. Smedby, Hanna Eriksson
Summary: This study investigated the association between metformin use and survival in diabetic patients with cutaneous melanoma. The results showed that metformin use was associated with improved overall survival regardless of timing and followed a dose-response pattern. However, no association was found between metformin use and melanoma-specific survival.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Oncology
Ida Wiken, Therese M-L Andersson, Cecilia Radkiewicz
Summary: This study investigates the impact of holidays on cancer incidence and survival rates in Sweden. It finds that cancer cases decline during holidays and increase post-holidays for certain types of cancer. The study also reveals higher mortality rates for cancers diagnosed during holidays, emphasizing the need for consistent cancer care throughout the year.
Article
Oncology
Alessia Visconti, Niccolo Rossi, Helena Deris, Karla A. Lee, Maja Hanic, Irena Trbojevic-Akmacic, Andrew M. Thomas, Laura A. Bolte, Johannes R. Bjork, Jahlisa S. Hooiveld-Noeken, Ruth Board, Mark Harland, Julia Newton-Bishop, Mark Harries, Joseph J. Sacco, Paul Lorigan, Heather M. Shaw, Elisabeth G. E. de Vries, Rudolf S. N. Fehrmann, Rinse K. Weersma, Tim D. Spector, Paul Nathan, Geke A. P. Hospers, Peter Sasieni, Veronique Bataille, Gordan Lauc, Mario Falchi
Summary: This study identifies novel glyco-markers of response and survival in melanoma patients receiving ICIs, demonstrating the potential for stratification of patients and the design of adjunct therapies.
Article
Health Care Sciences & Services
Nikolaos Skourlis, Michael J. Crowther, Therese M-L. Andersson, Donghao Lu, Mats Lambe, Paul C. Lambert
Summary: This study uses multi-state models to explore different research questions and modelling choices in the analysis of repeated prescriptions data. The results show that more complex multi-state structures can effectively capture the intermittent nature of medication use.
BMC MEDICAL RESEARCH METHODOLOGY
(2023)
Article
Oncology
Peter Sasieni, Rebecca Smittenaar, Earl Hubbell, John Broggio, Richard D. Neal, Charles Swanton
Summary: Background screening programmes using blood-based multi-cancer early detection (MCED) tests can reduce cancer burden through early diagnosis.
BRITISH JOURNAL OF CANCER
(2023)
Article
Medicine, Research & Experimental
Adam R. Brentnall, Chris Mathews, Sandy Beare, Jennifer Ching, Michelle Sleeth, Peter Sasieni
Summary: A computer algorithm was developed to target trial invitations and address healthy volunteer effects and inequity in health research studies. The algorithm sends invitations by sampling from lists generated by the algorithm, with a tilt towards less likely groups to achieve equity, and requires a minimum expected event rate for the primary outcome.
Article
Oncology
Cecilia Radkiewicz, Therese M-L Andersson, Jesper Lagergren
Summary: This study calculated years of life lost (YLL) due to the top 10 solid tumors causing the most deaths, using data from the Swedish National Cancer and Cause of Death Registers. The results showed that lung and colorectal cancer remained the leading causes of YLL, while pancreatic and breast cancer moved up in rank. Prostate cancer, on the other hand, moved down in rank. Women consistently lost more life years due to lung and pancreatic cancer, and the decline in colorectal cancer mortality was only reflected as a YLL decline in women. YLL is a simple and intuitive measure that expands our understanding of the cancer burden on society.
JNCI CANCER SPECTRUM
(2023)
Article
Oncology
Amar S. Ahmad, Judith Offman, Christine Delon, Bernard V. North, Jon Shelton, Peter D. Sasieni
Summary: The study investigated the application of years of life lost (YLL) in routine cancer statistics and found that lung, bowel, and breast cancer contributed the most to YLL. YLL is a useful measure that highlights the impact of cancer deaths on younger individuals.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Harry Hill, Ben Kearns, Nora Pashayan, Cristina Roadevin, Peter Sasieni, Judith Offman, Stephen Duffy
Summary: Risk-stratified breast cancer screening has the potential to be beneficial for women at the population level, but the net health benefit will depend on the particular risk-based strategy.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Tor Age Myklebust, Bjarte Aagnes, Yngvar Nilssen, Mark Rutherford, Paul C. Lambert, Therese M. L. Andersson, Anna L. V. Johansson, Paul W. Dickman, Bjorn Moller
Summary: Background: Routine reporting of cancer patient survival is vital for monitoring healthcare effectiveness and prognosis. Objective: This study aims to explore the feasibility of automating the production of these statistics. Results: We obtained reliable estimates of survival rates for most cancer types. Discussion: Implementing new survival measures in routine publications may be challenging, but we propose a method for automating the production of these statistics.
BRITISH JOURNAL OF CANCER
(2023)
Article
Medicine, General & Internal
James W. F. Catto, Bernard North, Megan Goff, Abigail Carter, Michelle Sleeth, Olena Mandrik, Jim Chilcott, Peter Sasieni, Marcus G. K. Cumberbatch
Summary: This study aims to test whether population screening in a region of high mortality risk will lead to a downward stage-migration of aggressive bladder cancer, improved survival, and cost-effectiveness.
Article
Oncology
Nivedha Raveinthiranathan, Jonathan Simkin, Robine Donken, Gina Ogilvie, Laurie Smith, Dirk Van Niekerk, Marette Lee, Ryan R. Woods
Summary: This study examined the trends in the incidence of invasive cervical cancer (ICC) in British Columbia (BC) by age and stage-at-diagnosis, relative to the World Health Organization's elimination targets. The study found that the incidence of ICC did not reach the elimination target, and declined from 18.88 to 7.08 per 100,000 persons from 1971 to 2017. The decline in incidence varied across different age groups, with a faster decline observed among older age groups.