Low frequency of GITR+ T cells in ex vivo and in vitro expanded Treg cells from type 1 diabetic patients

CD4+CD25+ Regulatory T Cell Repertoire Formation Shaped by Differential Presentation of Peptides from a Self-Antigen

(2014) J. Larkin et al.   JOURNAL OF IMMUNOLOGY

The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells

(2014) A. Schneider et al.   JOURNAL OF IMMUNOLOGY

Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells

(2012) Yijun Carrier et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Novel IL-10-Independent Regulatory Role for B Cells in Suppressing Autoimmunity by Maintenance of Regulatory T Cells via GITR Ligand

(2012) A. Ray et al.   JOURNAL OF IMMUNOLOGY

Pharmacological modulation of GITRL/GITR system: therapeutic perspectives

(2011) Giuseppe Nocentini et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

(2011) Alessandra Ferraro et al.   DIABETES

CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity

(2011) Rodolfo Bianchini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

(2011) Stephanie A. McClymont et al.   JOURNAL OF IMMUNOLOGY

Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation

(2010) Theresa Placke et al.   Clinical & Developmental Immunology

Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects

(2009) S. A. Long et al.   DIABETES

Functional islet-specific Treg can be generated from CD4+CD25− T cells of healthy and type 1 diabetic subjects

(2009) S. Alice Long et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MS4A4B Is a GITR-Associated Membrane Adapter, Expressed by Regulatory T Cells, Which Modulates T Cell Activation

(2009) D. Howie et al.   JOURNAL OF IMMUNOLOGY

GITR Triggering Induces Expansion of Both Effector and Regulatory CD4+ T Cells In Vivo

(2009) R. W. van Olffen et al.   JOURNAL OF IMMUNOLOGY

Apoptosis of CD4+CD25high T Cells in Type 1 Diabetes May Be Partially Mediated by IL-2 Deprivation

(2009) Parthav Jailwala et al.   PLoS One

APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes

(2008) Yulan Jin et al.   CLINICAL IMMUNOLOGY

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related (GITR)-Fc Fusion Protein Inhibits GITR Triggering and Protects from the Inflammatory Response after Spinal Cord Injury

(2008) G. Nocentini et al.   MOLECULAR PHARMACOLOGY