Early events governing memory CD8+ T-cell differentiation

Once a killer, always a killer: from cytotoxic T cell to memory cell

(2015) Leo Lefrançois et al.   IMMUNOLOGICAL REVIEWS

FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase

(2014) S. Fabre et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD4+ T Cell-Derived IL-2 Is Essential for Help-Dependent Primary CD8+ T Cell Responses

(2014) E. B. Wilson et al.   JOURNAL OF IMMUNOLOGY

Memory CD8+ T cell differentiation

(2010) Joshua J. Obar et al.   Annals of the New York Academy of Sciences

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

The mTOR Kinase Determines Effector versus Memory CD8 + T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

(2010) Rajesh R. Rao et al.   IMMUNITY

Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell–licensed DCs

(2010) Verena Semmling et al.   NATURE IMMUNOLOGY

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

(2010) Marina Rode von Essen et al.   NATURE IMMUNOLOGY

Effector T-cell differentiation during viral and bacterial infections: Role of direct IL-12 signals for cell fate decision of CD8+T cells

(2009) Selina J. Keppler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An Essential Role of the Forkhead-Box Transcription Factor Foxo1 in Control of T Cell Homeostasis and Tolerance

(2009) Weiming Ouyang et al.   IMMUNITY

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Opposing Effects of TGF-β and IL-15 Cytokines Control the Number of Short-Lived Effector CD8+ T Cells

(2009) Shomyseh Sanjabi et al.   IMMUNITY

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

(2009) Victor Peperzak et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

(2009) David K. Finlay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recall Responses by Helpless Memory CD8+ T Cells Are Restricted by the Up-Regulation of PD-1

(2009) S. Fuse et al.   JOURNAL OF IMMUNOLOGY

A Default Pathway of Memory CD8 T Cell Differentiation after Dendritic Cell Immunization Is Deflected by Encounter with Inflammatory Cytokines during Antigen-Driven Proliferation

(2009) N.-L. L. Pham et al.   JOURNAL OF IMMUNOLOGY

Phosphoinositide (3,4,5)-Triphosphate Binding to Phosphoinositide-Dependent Kinase 1 Regulates a Protein Kinase B/Akt Signaling Threshold That Dictates T-Cell Migration, Not Proliferation

(2009) C. Waugh et al.   MOLECULAR AND CELLULAR BIOLOGY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

The cunning little vixen: Foxo and the cycle of life and death

(2009) Stephen M Hedrick   NATURE IMMUNOLOGY

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

(2009) Yann M Kerdiles et al.   NATURE IMMUNOLOGY

CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses

(2009) J. J. Obar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secondary Replicative Function of CD8+ T Cells That Had Developed an Effector Phenotype

(2009) O. Bannard et al.   SCIENCE

IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response

(2008) M. P. Rubinstein et al.   BLOOD

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

(2008) C. S. Hinrichs et al.   BLOOD

In situ imaging reveals different responses by naïve and memory CD8 T cells to late antigen presentation by lymph node DC after influenza virus infection

(2008) Kamal M. Khanna et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

(2008) Surojit Sarkar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

(2008) Linda V Sinclair et al.   NATURE IMMUNOLOGY