ERAP2functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers

ERAP2is associated with ankylosing spondylitis inHLA-B27-positive andHLA-B27-negative patients

(2015) Philip C Robinson et al.   ANNALS OF THE RHEUMATIC DISEASES

ERAP1 biology and assessment in Ankylosing Spondylitis

(2015) Philip C. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis

(2014) T J Kenna et al.   GENES AND IMMUNITY

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy

(2014) Jonas J.W. Kuiper et al.   HUMAN MOLECULAR GENETICS

Functionally distinctERAP1allotype combinations distinguish individuals with Ankylosing Spondylitis

(2014) Emma Reeves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of ankylosing spondylitis

(2013) Philip C. Robinson et al.   MOLECULAR IMMUNOLOGY

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

(2013) Adrian Cortes et al.   NATURE GENETICS

Microbes, the gut and ankylosing spondylitis

(2013) Mary-Ellen Costello et al.   ARTHRITIS RESEARCH & THERAPY

Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis

(2012) Nigil Haroon et al.   ANNALS OF THE RHEUMATIC DISEASES

A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

(2012) I. Evnouchidou et al.   JOURNAL OF IMMUNOLOGY

Functional Interaction of the Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 Polymorphism and HLA-B27in Vivo

(2012) Noel García-Medel et al.   MOLECULAR & CELLULAR PROTEOMICS

The Genetics of Ankylosing Spondylitis and Axial Spondyloarthritis

(2012) Philip C. Robinson et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

(2011) Tony J. Kenna et al.   ARTHRITIS AND RHEUMATISM

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics