TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2

The C-Terminal Module IV of Connective Tissue Growth Factor, Through EGFR/Nox1 Signaling, Activates the NF-κB Pathway and Proinflammatory Factors in Vascular Smooth Muscle Cells

(2015) Raúl R. Rodrigues-Diez et al.   ANTIOXIDANTS & REDOX SIGNALING

CCN2: a novel, specific and valid target for anti-fibrotic drug intervention

(2013) Andrew Leask   EXPERT OPINION ON THERAPEUTIC TARGETS

Foxp3+ Treg cells in humoral immunity

(2013) James B. Wing et al.   INTERNATIONAL IMMUNOLOGY

The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response

(2013) Raquel Rodrigues-Díez et al.   LABORATORY INVESTIGATION

Connective tissue growth factor is a new ligand of epidermal growth factor receptor

(2013) Sandra Rayego-Mateos et al.   Journal of Molecular Cell Biology

CCN2: a master regulator of the genesis of bone and cartilage

(2013) Masaharu Takigawa   Journal of Cell Communication and Signaling

Targeting chemokines in proteinuria-induced renal disease

(2012) Juan Antonio Moreno et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells

(2011) Helen C. O'Donovan et al.   BIOCHEMICAL JOURNAL

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

Role of Treg Cells and TGF-β1 in Patients with Systemic Lupus Erythematosus: A Possible Relation with Lupus Nephritis

(2011) Qian Xing et al.   IMMUNOLOGICAL INVESTIGATIONS

Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro

(2011) Xiao-Ming Meng et al.   JOURNAL OF PATHOLOGY

Blocking TGF- 1 Protects the Peritoneal Membrane from Dialysate-Induced Damage

(2011) J. Loureiro et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis

(2011) Qian Xing et al.   RHEUMATOLOGY INTERNATIONAL

The CCN family: A new class of inflammation modulators?

(2010) L. Kular et al.   BIOCHIMIE

Blockade of TGF-β by catheter-based local intravascular gene delivery does not alter the in-stent neointimal response, but enhances inflammation in pig coronary arteries

(2010) Ick-Mo Chung et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

(2010)   LANCET

N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan

(2009) Eriko Aoyama et al.   BIOCHEMICAL JOURNAL

Urinary monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth factor (CCN2) as prognostic markers for progression of diabetic nephropathy

(2009) Frederick W.K. Tam et al.   CYTOKINE

Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

(2009) Jyoti Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitium by Activating NF- B

(2009) E. Sanchez-Lopez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure

(2008) Norimichi Koitabashi et al.   EUROPEAN JOURNAL OF HEART FAILURE

Connective tissue growth factor: Structure–function relationships of a mosaic, multifunctional protein

(2008) Patricia De Winter et al.   GROWTH FACTORS

Functions and mechanisms of action of CCN matricellular proteins

(2008) Chih-Chiun Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation

(2008) Gisselle Carvajal et al.   KIDNEY INTERNATIONAL

Neutrophil gelatinase‐associated lipocalin (NGAL): A new marker of kidney disease

(2008) Peasad Devarajan   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION