Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives

Artesunate Ameliorates Functional Limitations in Freund’s Complete Adjuvant-Induced Monoarthritis in Rat by Maintaining Oxidative Homeostasis and Inhibiting COX-2 Expression

(2014) B. Guruprasad et al.   INFLAMMATION

Artesunate Abolishes Germinal Center B Cells and Inhibits Autoimmune Arthritis

(2014) Lifei Hou et al.   PLoS One

Anti-Malarial Drug Artesunate Inhibits Primary Human Cultured Airway Smooth Muscle Cell Proliferation

(2013) Sheryl S L Tan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Artemisinin Analogue SM934 Ameliorates Murine Experimental Autoimmune Encephalomyelitis through Enhancing the Expansion and Functions of Regulatory T Cell

(2013) Xin Li et al.   PLoS One

Qinghaosu (artemisinin): Chemistry and pharmacology

(2012) Ying Li   ACTA PHARMACOLOGICA SINICA

Anti-allergic action of anti-malarial drug artesunate in experimental mast cell-mediated anaphylactic models

(2012) C. Cheng et al.   ALLERGY

Dihydroartemisinin Ameliorates Inflammatory Disease by Its Reciprocal Effects on Th and Regulatory T Cell Function via Modulating the Mammalian Target of Rapamycin Pathway

(2012) Yan G. Zhao et al.   JOURNAL OF IMMUNOLOGY

SM934 Treated Lupus-Prone NZB×NZW F1 Mice by Enhancing Macrophage Interleukin-10 Production and Suppressing Pathogenic T Cell Development

(2012) Li-Fei Hou et al.   PLoS One

Oral administration of artemisinin analog SM934 ameliorates lupus syndromes in MRL/lpr mice by inhibiting Th1 and Th17 cell responses

(2011) Li-Fei Hou et al.   ARTHRITIS AND RHEUMATISM

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

(2011) Chang Cheng et al.   PLoS One

SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-κB pathways in RAW 264.7 macrophages

(2009) Jun-xia Wang et al.   ACTA PHARMACOLOGICA SINICA

SM934, a water-soluble derivative of arteminisin, exerts immunosuppressive functions in vitro and in vivo

(2009) Li-Fei Hou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dihydroartemisinin can inhibit calmodulin, calmodulin-dependent phosphodiesterase activity and stimulate cellular immune responses

(2009) Shokoofe Noori et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte

(2009) Ya He et al.   RHEUMATOLOGY INTERNATIONAL

The new water-soluble artemisinin derivative SM905 ameliorates collagen-induced arthritis by suppression of inflammatory and Th17 responses

(2008) J-X Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

(2008) Chris J. Hedegaard et al.   IMMUNOLOGY

Artemisinin can inhibit the calmodulin-mediated activation of phosphodiesterase in comparison with Cyclosporin A

(2008) S. Noori et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE

Investigation of the immunosuppressive activity of artemether on T-cell activation and proliferation

(2007) J-X Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY