Emerging Role of SIGIRR rs7396562(T/G) Polymorphism in Systemic Lupus Erythematosus in a Chinese Population

Therapeutic potential of SIGIRR in systemic lupus erythematosus

(2013) Chao Wang et al.   RHEUMATOLOGY INTERNATIONAL

Understanding the contribution of synonymous mutations to human disease

(2011) Zuben E. Sauna et al.   NATURE REVIEWS GENETICS

SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis

(2010) Stefan K. Drexler et al.   ARTHRITIS AND RHEUMATISM

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

The Receptor SIGIRR Suppresses Th17 Cell Proliferation via Inhibition of the Interleukin-1 Receptor Pathway and mTOR Kinase Activation

(2010) Muhammet F. Gulen et al.   IMMUNITY

C1q inhibits immune complex-induced interferon-α production in plasmacytoid dendritic cells: A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

(2009) Christian Lood et al.   ARTHRITIS AND RHEUMATISM

High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein

(2009) Daniela Novick et al.   JOURNAL OF AUTOIMMUNITY

The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response

(2009) K. Bulek et al.   JOURNAL OF IMMUNOLOGY

Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis

(2009) Maciej Lech et al.   JOURNAL OF PATHOLOGY

The Role of Extracellular DNA in Autoimmunity in SLE

(2009) K.-Y. Su et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization

(2009) Cecilia Garlanda et al.   TRENDS IN IMMUNOLOGY

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens

(2008) Maciej Lech et al.   JOURNAL OF EXPERIMENTAL MEDICINE