Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB

Cutting Edge: TLR2 Is a Functional Receptor for Acute-Phase Serum Amyloid A

(2014) N. Cheng et al.   JOURNAL OF IMMUNOLOGY

Targeting TLR2 Attenuates Pulmonary Inflammation and Fibrosis by Reversion of Suppressive Immune Microenvironment

(2014) H.-Z. Yang et al.   JOURNAL OF IMMUNOLOGY

Role of toll-like receptors in systemic sclerosis

(2013) Marzena Ciechomska et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Upregulation of Toll-like receptor 2 gene expression by acetylation of AP-2 alpha in THP-1 cells, a human monocytic cell line

(2013) Miao Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Acute-Phase Serum Amyloid A in Osteoarthritis: Regulatory Mechanism and Proinflammatory Properties

(2013) Dominique de Seny et al.   PLoS One

Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts

(2012) Thomas Hügle et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6, its role in fibrosing conditions

(2012) Steven O’Reilly et al.   CYTOKINE & GROWTH FACTOR REVIEWS

T cells in systemic sclerosis: a reappraisal

(2012) S. O'Reilly et al.   RHEUMATOLOGY

Association of C-reactive protein with high disease activity in systemic sclerosis: Results from the Canadian Scleroderma Research Group

(2012) Chayawee Muangchan et al.   ARTHRITIS CARE & RESEARCH

Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts

(2012) Kiyoshi Migita et al.   ARTHRITIS RESEARCH & THERAPY

Acute serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis

(2011) M. Connolly et al.   ANNALS OF THE RHEUMATIC DISEASES

A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

(2011) J. C. A. Broen et al.   ARTHRITIS AND RHEUMATISM

Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy

(2011) Mary Connolly et al.   ARTHRITIS AND RHEUMATISM

Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways

(2011) K. D. Nguyen et al.   BLOOD

Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) Attenuates Interleukin-6 (IL-6)-induced Collagen Synthesis and Resultant Hypertrophy in Rat Heart

(2011) Saiful Anam Mir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

(2011) K. Niemi et al.   JOURNAL OF IMMUNOLOGY

Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

(2011) Sinéad Nic An Ultaigh et al.   ARTHRITIS RESEARCH & THERAPY

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts

(2011) Heidi Wähämaa et al.   ARTHRITIS RESEARCH & THERAPY

Could antibodies against Serum Amyloid A function as physiological regulators in humans?

(2010) Katja Lakota et al.   AUTOIMMUNITY

Fibrosis and immune dysregulation in systemic sclerosis

(2010) Carlo Chizzolini et al.   AUTOIMMUNITY REVIEWS

Serum amyloid A induces reactive oxygen species (ROS) production and proliferation of fibroblast

(2010) E. Hatanaka et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Toll-like receptors expressed by dermal fibroblasts contribute to hypertrophic scarring

(2010) JianFei Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells

(2009) C Ward et al.   THORAX

Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2

(2008) R. L. He et al.   BLOOD

Immunohistochemical characterization of the cellular infiltrate in localized scleroderma

(2008) Yong Xie et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts

(2008) Martha R. Watson et al.   JOURNAL OF HEPATOLOGY

Vascular Disease in Scleroderma: Mechanisms of Vascular Injury

(2008) Bashar Kahaleh   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA