Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates

(2011) P. W. Denton et al.   JOURNAL OF VIROLOGY

Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2Rγ−/− (NSG) BLT mice

(2011) Cheryl A. Stoddart et al.   VIROLOGY

Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rγnull mice

(2010) Deepika Rajesh et al.   HUMAN IMMUNOLOGY

Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice

(2010) Paul W. Denton et al.   PLoS One

Lentiviral Vector Delivery of Human Interleukin-7 (hIL-7) to Human Immune System (HIS) Mice Expands T Lymphocyte Populations

(2010) Ryan M. O'Connell et al.   PLoS One

Generation of Human Antigen-Specific Monoclonal IgM Antibodies Using Vaccinated “Human Immune System” Mice

(2010) Pablo D. Becker et al.   PLoS One

Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/−γc−/−, and C.B-17-scid/bg immunodeficient mice

(2009) Christin M. Lepus et al.   HUMAN IMMUNOLOGY

The analysis of the functions of human B and T cells in humanized NOD/shi-scid/γcnull (NOG) mice (hu-HSC NOG mice)

(2009) Yohei Watanabe et al.   INTERNATIONAL IMMUNOLOGY

IL-7 Enhances Thymic Human T Cell Development in "Human Immune System" Rag2-/-IL-2R c-/- Mice without Affecting Peripheral T Cell Homeostasis

(2009) A. U. van Lent et al.   JOURNAL OF IMMUNOLOGY

Identification and Characterization of a Human CD5+ Pre-Naive B Cell Population

(2009) J. Lee et al.   JOURNAL OF IMMUNOLOGY

Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

(2009) D. M. Brainard et al.   JOURNAL OF VIROLOGY

Renaissance for mouse models of human hematopoiesis and immunobiology

(2009) Markus G Manz et al.   NATURE IMMUNOLOGY

Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγnull Mice

(2009) Smita Jaiswal et al.   PLoS One

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

(2009) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IC31®, a Two-Component Novel Adjuvant Mixed with a Conjugate Vaccine Enhances Protective Immunity against Pneumococcal Disease in Neonatal Mice

(2009) T. A. Olafsdottir et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model

(2008) N. Tonomura et al.   BLOOD

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+B cells

(2008) Ferenc A. Scheeren et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

(2008) N. A. Doria-Rose et al.   JOURNAL OF VIROLOGY

Human BLyS Facilitates Engraftment of Human PBL Derived B Cells in Immunodeficient Mice

(2008) Madelyn R. Schmidt et al.   PLoS One

The novel adjuvant IC31® strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice

(2008) Karin Riedl et al.   VACCINE

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

(2008) Paul W Denton et al.   PLOS MEDICINE