Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis

Activation of NF- B1 by OX40 Contributes to Antigen-Driven T Cell Expansion and Survival

(2014) J. Song et al.   JOURNAL OF IMMUNOLOGY

IKK biology

(2012) Fei Liu et al.   IMMUNOLOGICAL REVIEWS

Ubiquitination in signaling to and activation of IKK

(2012) Zhijian J. Chen   IMMUNOLOGICAL REVIEWS

Regulation of NF-κB by ubiquitination and degradation of the IκBs

(2012) Naama Kanarek et al.   IMMUNOLOGICAL REVIEWS

Regulation of NF-κB by deubiquitinases

(2012) Edward W. Harhaj et al.   IMMUNOLOGICAL REVIEWS

NF-κB subunit specificity in hemopoiesis

(2012) Steve Gerondakis et al.   IMMUNOLOGICAL REVIEWS

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Pathogenic Mechanisms of HIV Disease

(2011) Susan Moir et al.   Annual Review of Pathology-Mechanisms of Disease

The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF- B signals

(2011) A. K. Kress et al.   BLOOD

How I treat adult T-cell leukemia/lymphoma

(2011) A. Bazarbachi et al.   BLOOD

Dephosphorylation of Bcl-10 by calcineurin is essential for canonical NF-κB activation in Th cells

(2011) Stefan Frischbutter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

The Ca2+-dependent Phosphatase Calcineurin Controls the Formation of the Carma1-Bcl10-Malt1 Complex during T Cell Receptor-induced NF-κB Activation

(2011) Lysann Palkowitsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitors of Histone Deacetylases

(2011) Kelly Huber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T-Cell Receptor Signaling Enhances Transcriptional Elongation from Latent HIV Proviruses by Activating P-TEFb through an ERK-Dependent Pathway

(2011) Young Kyeung Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

(2011) S. Xing et al.   JOURNAL OF VIROLOGY

Human T Cell Leukemia Virus Type 1 Tax Inhibits Innate Antiviral Signaling via NF- B-Dependent Induction of SOCS1

(2011) S. Charoenthongtrakul et al.   JOURNAL OF VIROLOGY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

(2011) Masoud Vedadi et al.   Nature Chemical Biology

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1

(2011) Noula Shembade et al.   NATURE IMMUNOLOGY

HIV latency is influenced by regions of the viral genome outside of the long terminal repeats and regulatory genes

(2011) Matthew D. Marsden et al.   VIROLOGY

NF-κB Hyper-Activation by HTLV-1 Tax Induces Cellular Senescence, but Can Be Alleviated by the Viral Anti-Sense Protein HBZ

(2011) Huijun Zhi et al.   PLoS Pathogens

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

(2010) Subash C. Gupta et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The tumor suppressor gene WWOX links the canonical and noncanonical NF- B pathways in HTLV-I Tax-mediated tumorigenesis

(2010) J. Fu et al.   BLOOD

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

(2010) Gilad Doitsh et al.   CELL

Bryostatin-1 Synergizes with Histone Deacetylase Inhibitors to Reactivate HIV-1 from Latency

(2010) Moises Perez et al.   CURRENT HIV RESEARCH

Activation of host pattern recognition receptors by viruses

(2010) Kiva Brennan et al.   CURRENT OPINION IN MICROBIOLOGY

Interleukin-7 promotes the survival of human CD4+effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway

(2010) Nizar Chetoui et al.   IMMUNOLOGY

Bryostatin-1, a Naturally Occurring Antineoplastic Agent, Acts as a Toll-like Receptor 4 (TLR-4) Ligand and Induces Unique Cytokines and Chemokines in Dendritic Cells

(2010) Maria Eugenia Ariza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294

(2010) Kenichi Imai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N Terminus of Adenovirus Type 12 E1A Inhibits Major Histocompatibility Complex Class I Expression by Preventing Phosphorylation of NF- B p65 Ser276 through Direct Binding

(2010) J. Jiao et al.   JOURNAL OF VIROLOGY

Viral Exploitation of Host SOCS Protein Functions

(2010) L. N. Akhtar et al.   JOURNAL OF VIROLOGY

Establishment of HIV Latency in Primary CD4+ Cells Is due to Epigenetic Transcriptional Silencing and P-TEFb Restriction

(2010) M. Tyagi et al.   JOURNAL OF VIROLOGY

Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants

(2010) J. C. Burnett et al.   JOURNAL OF VIROLOGY

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

(2010) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

(2010) Dan Levy et al.   NATURE IMMUNOLOGY

The HTLV-1 tax protein cooperates with phosphorylated CREB, TORC2 and p300 to activate CRE-dependent cyclin D1 transcription

(2010) Y-M Kim et al.   ONCOGENE

Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection

(2010) Nancie M. Archin et al.   PLoS One

Hematopoietic stem cells and retroviral infection

(2010) Prabal Banerjee et al.   Retrovirology

Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

(2010) N. Shembade et al.   SCIENCE

NF-κB/Rel: agonist and antagonist roles in HIV-1 latency

(2010) Jonathan KL Chan et al.   Current Opinion in HIV and AIDS

HTLV-1 Evades Type I Interferon Antiviral Signaling by Inducing the Suppressor of Cytokine Signaling 1 (SOCS1)

(2010) Stéphanie Olière et al.   PLoS Pathogens

The Role of Ubiquitin in NF-κB Regulatory Pathways

(2009) Brian Skaug et al.   Annual Review of Biochemistry

PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

(2009) P. Yan et al.   BLOOD

Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit

(2009) Xiao-Dong Yang et al.   EMBO JOURNAL

HTLV-1 Tax Is a Critical Lipid Raft Modulator That Hijacks IκB Kinases to the Microdomains for Persistent Activation of NF-κB

(2009) Jiannan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of HIV-1 Activation by NF-κB—A Higher-Order Complex of p50:RelA Bound to the HIV-1 LTR

(2009) James C. Stroud et al.   JOURNAL OF MOLECULAR BIOLOGY

Determinants of the Establishment of Human Immunodeficiency Virus Type 1 Latency

(2009) A. Duverger et al.   JOURNAL OF VIROLOGY

Human Immunodeficiency Virus Type 1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells

(2009) B. P. Doehle et al.   JOURNAL OF VIROLOGY

Peptidylproline cis-trans-Isomerase Pin1 Interacts with Human T-Cell Leukemia Virus Type 1 Tax and Modulates Its Activation of NF- B

(2009) J.-M. Peloponese et al.   JOURNAL OF VIROLOGY

Stromal Cell-Mediated Suppression of Human T-Cell Leukemia Virus Type 1 Expression In Vitro and In Vivo by Type I Interferon

(2009) S. Kinpara et al.   JOURNAL OF VIROLOGY

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

(2009) Seok-Rae Park et al.   NATURE IMMUNOLOGY

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

(2009) Weifeng Xu et al.   NATURE IMMUNOLOGY

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Synergistic Activation of HIV-1 Expression by Deacetylase Inhibitors and Prostratin: Implications for Treatment of Latent Infection

(2009) Sophie Reuse et al.   PLoS One

Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2

(2009) Toshiyuki Shoji et al.   Retrovirology

A historical reflection on the discovery of human retroviruses

(2009) Anders Vahlne   Retrovirology

The Challenge of Finding a Cure for HIV Infection

(2009) D. D. Richman et al.   SCIENCE

Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-κB pathway

(2009) Julie Lodewick et al.   VIROLOGY

Control of Stochastic Gene Expression by Host Factors at the HIV Promoter

(2009) John C. Burnett et al.   PLoS Pathogens

NRP/Optineurin Cooperates with TAX1BP1 to Potentiate the Activation of NF-κB by Human T-Lymphotropic Virus Type 1 Tax Protein

(2009) Chloé Journo et al.   PLoS Pathogens

CpG Methylation Controls Reactivation of HIV from Latency

(2009) Jana Blazkova et al.   PLoS Pathogens

Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation

(2009) Steven E. Kauder et al.   PLoS Pathogens

Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation

(2008) J. Arnold et al.   BLOOD

Overexpressed NF- B-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells

(2008) Y. Saitoh et al.   BLOOD

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF- B

(2008) T. Zhao et al.   BLOOD

Rearranged NF-κB2 gene in an adult T-cell leukemia cell line

(2008) Masato Isogawa et al.   CANCER SCIENCE

Reduction of human T-cell leukemia virus type-1 infection in mice lacking nuclear factor-κB-inducing kinase

(2008) Takayuki Nitta et al.   CANCER SCIENCE

Orientation-Dependent Regulation of Integrated HIV-1 Expression by Host Gene Transcriptional Readthrough

(2008) Yefei Han et al.   Cell Host & Microbe

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

Human Immunodeficiency Virus Type 1 Tat Protein Inhibits the SIRT1 Deacetylase and Induces T Cell Hyperactivation

(2008) Hye-Sook Kwon et al.   Cell Host & Microbe

Transcriptional Interference Antagonizes Proviral Gene Expression to Promote HIV Latency

(2008) Tina Lenasi et al.   Cell Host & Microbe

PP2B and PP1  cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

(2008) R. Chen et al.   GENES & DEVELOPMENT

The Proto-Oncogene Bcl3, Induced by Tax, Represses Tax-Mediated Transcription via p300 Displacement from the Human T-Cell Leukemia Virus Type 1 Promoter

(2008) Y.-M. Kim et al.   JOURNAL OF VIROLOGY

RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF- B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes

(2008) D. E. Nowak et al.   MOLECULAR AND CELLULAR BIOLOGY

Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA

(2008) B. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Activation of the cyclin D2 and cdk6 genes through NF-κB is critical for cell-cycle progression induced by HTLV-I Tax

(2008) R Iwanaga et al.   ONCOGENE

Control of canonical NF- B activation through the NIK-IKK complex pathway

(2008) B. Zarnegar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

Differential effects of phorbol-13-monoesters on human immunodeficiency virus reactivation

(2007) Nieves Márquez et al.   BIOCHEMICAL PHARMACOLOGY