The diverse roles of IRF4 in late germinal center B-cell differentiation

STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

(2014) S. A. Diehl et al.   JOURNAL OF IMMUNOLOGY

IMiD immunomodulatory compounds block C/EBP  translation through eIF4E down-regulation resulting in inhibition of MM

(2011) S. Li et al.   BLOOD

IRF4 mutations in chronic lymphocytic leukemia

(2011) V. Havelange et al.   BLOOD

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

(2011) I. Salaverria et al.   BLOOD

Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response

(2011) Antonia Lopez-Girona et al.   BRITISH JOURNAL OF HAEMATOLOGY

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

Fine tuning of IRF-4 expression by SWAP-70 controls the initiation of plasma cell development

(2011) Michaël Chopin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular Pathogenesis of Hodgkin's Lymphoma: Increasing Evidence of the Importance of the Microenvironment

(2011) Christian Steidl et al.   JOURNAL OF CLINICAL ONCOLOGY

An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling

(2011) R. Sciammas et al.   Molecular Systems Biology

IRF4 Is a Suppressor of c-Myc Induced B Cell Leukemia

(2011) Simanta Pathak et al.   PLoS One

The genetic network controlling plasma cell differentiation

(2011) Stephen L. Nutt et al.   SEMINARS IN IMMUNOLOGY

Inherited genetic susceptibility to monoclonal B-cell lymphocytosis

(2010) D. Crowther-Swanepoel et al.   BLOOD

Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis

(2010) S.-H. Jo et al.   BLOOD

BLIMP1 Is a Tumor Suppressor Gene Frequently Disrupted in Activated B Cell-like Diffuse Large B Cell Lymphoma

(2010) Jonathan Mandelbaum et al.   CANCER CELL

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

(2010) Akihiko Muto et al.   EMBO JOURNAL

Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells

(2010) Nichol E. Holodick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fine-scale mapping of the 6p25.3 chronic lymphocytic leukaemia susceptibility locus

(2010) Dalemari Crowther-Swanepoel et al.   HUMAN MOLECULAR GENETICS

IFN Regulatory Factor 8 Restricts the Size of the Marginal Zone and Follicular B Cell Pools

(2010) J. Feng et al.   JOURNAL OF IMMUNOLOGY

Monoclonal B-cell lymphocytosis (MBL): biology, natural history and clinical management

(2010) T D Shanafelt et al.   LEUKEMIA

Ikaros and Aiolos Inhibit Pre-B-Cell Proliferation by Directly Suppressing c-Myc Expression

(2010) S. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

(2009) M. Jourdan et al.   BLOOD

IRF4 is modulated by CD40L and by apoptotic and anti-proliferative signals in Hodgkin lymphoma

(2009) Donatella Aldinucci et al.   BRITISH JOURNAL OF HAEMATOLOGY

IRF4: Immunity. Malignancy! Therapy?

(2009) A. L. Shaffer et al.   CLINICAL CANCER RESEARCH

Stepwise Activation of Enhancer and Promoter Regions of the B Cell Commitment Gene Pax5 in Early Lymphopoiesis

(2009) Thorsten Decker et al.   IMMUNITY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

Blimp-1/Prdm1 Alternative Promoter Usage during Mouse Development and Plasma Cell Differentiation

(2009) M. A. J. Morgan et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

IRF-4 functions as a tumor suppressor in early B-cell development

(2008) J. Acquaviva et al.   BLOOD

IRF-4-Binding Protein Inhibits Interleukin-17 and Interleukin-21 Production by Controlling the Activity of IRF-4 Transcription Factor

(2008) Qinzhong Chen et al.   IMMUNITY

Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling

(2008) Kristen Johnson et al.   IMMUNITY

Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6

(2008) K. Ochiai et al.   INTERNATIONAL IMMUNOLOGY

A Role for Interferon Regulatory Factor 4 in Receptor Editing

(2008) S. Pathak et al.   MOLECULAR AND CELLULAR BIOLOGY

IRF4 addiction in multiple myeloma

(2008) Arthur L. Shaffer et al.   NATURE

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

(2008) Maria Chiara Di Bernardo et al.   NATURE GENETICS

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

(2008) G. Lenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA