Type 1 diabetes in mice and men: gene expression profiling to investigate disease pathogenesis

Diminished Adenosine A1 Receptor Expression in Pancreatic  -Cells May Contribute to the Pathology of Type 1 Diabetes

(2014) L. Yip et al.   DIABETES

Normal and aberrant splicing ofLMNA

(2014) Yue-Bei Luo et al.   JOURNAL OF MEDICAL GENETICS

Alternative Splice Forms of CTLA-4 Induced by Antisense Mediated Splice-Switching Influences Autoimmune Diabetes Susceptibility in NOD Mice

(2014) Dan V. Mourich et al.   Nucleic Acid Therapeutics

Type 1 Diabetes: Prospective Cohort Studies for Identification of the Environmental Trigger

(2013) Kjersti S. Rønningen   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice

(2013) P. G. Larsson et al.   DIABETOLOGIA

Gene expression changes underlying cortical pathology: clues to understanding neurological disability in multiple sclerosis

(2013) Ranjan Dutta   Multiple Sclerosis Journal

Low Incidence of Spontaneous Type 1 Diabetes in Non-Obese Diabetic Mice Raised on Gluten-Free Diets Is Associated with Changes in the Intestinal Microbiome

(2013) Eric V. Marietta et al.   PLoS One

Changing faces, unmasking the beta-cell

(2013) Menno van Lummel et al.   Current Opinion in Endocrinology Diabetes and Obesity

Intersection between genetic polymorphisms and immune deviation in type 1 diabetes

(2013) Alice Long et al.   Current Opinion in Endocrinology Diabetes and Obesity

Genetics of Type 1 Diabetes

(2013) J. A. Noble et al.   Cold Spring Harbor Perspectives in Medicine

Environmental Triggers of Type 1 Diabetes

(2013) M. Knip et al.   Cold Spring Harbor Perspectives in Medicine

Improved blood glucose disposal and altered insulin secretion patterns in adenosine A1 receptor knockout mice

(2012) Gary K. Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Antisense oligonucleotide mediated exon skipping as a potential strategy for the treatment of a variety of inflammatory diseases such as rheumatoid arthritis

(2012) Seda Yilmaz-Elis et al.   ANNALS OF THE RHEUMATIC DISEASES

What is the key environmental trigger in type 1 diabetes — Is it viruses, or wheat gluten, or both?

(2012) William E. Barbeau   AUTOIMMUNITY REVIEWS

PTPN22 Alters the Development of Regulatory T Cells in the Thymus

(2012) C. J. Maine et al.   JOURNAL OF IMMUNOLOGY

LYP inhibits T-cell activation when dissociated from CSK

(2012) Torkel Vang et al.   Nature Chemical Biology

Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3

(2012) Linda Yip et al.   Journal of Molecular Cell Biology

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

(2012) Décio L. Eizirik et al.   PLoS Genetics

RNA splicing: disease and therapy

(2011) A. G. L. Douglas et al.   Briefings in Functional Genomics

Genetics of Type 1 Diabetes: What's Next?

(2010) F. Pociot et al.   DIABETES

Male and female NOD mice differentially express peroxisome proliferator-activated receptors and pathogenic cytokines

(2010) Nik Soriani Yaacob et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct

(2009) Ellen F. Young et al.   AUTOIMMUNITY

Microarray Analysis of Autoimmune Diseases by Machine Learning Procedures

(2009) R. Armananzas et al.   IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE

A Large-Scale RNAi Screen Identifies Deaf1 as a Regulator of Innate Immune Responses in Drosophila

(2009) David Kuttenkeuler et al.   Journal of Innate Immunity

Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

(2009) Maria Kinali et al.   LANCET NEUROLOGY

Absence of adenosine A1 receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin

(2009) Albert Salehi et al.   LIFE SCIENCES

Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes

(2009) Amanda J. MacFarlane et al.   MAMMALIAN GENOME

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

(2009) Linda Yip et al.   NATURE IMMUNOLOGY

Genetics of Type 1A Diabetes

(2009) Patrick Concannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic Potential of Splice-Switching Oligonucleotides

(2009) John Bauman et al.   OLIGONUCLEOTIDES

Tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice

(2008) Keiichi Kodama et al.   CLINICAL IMMUNOLOGY

On the Pathogenicity of Autoantigen-Specific T-Cell Receptors

(2008) A. R. Burton et al.   DIABETES

DEAF-1 regulates immunity gene expression in Drosophila

(2008) D. E. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients

(2008) I. Gavanescu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA