Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis

HCC Development Is Associated to Peripheral Insulin Resistance in a Mouse Model of NASH

(2014) Samuele De Minicis et al.   PLoS One

Mineralocorticoid receptor in adipocytes and macrophages: A promising target to fight metabolic syndrome

(2014) Vincenzo Marzolla et al.   STEROIDS

Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet

(2013) Tsutomu Wada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pathophysiology of NASH: Perspectives for a Targeted Treatment

(2013) Fabio Marra et al.   CURRENT PHARMACEUTICAL DESIGN

Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice

(2013) P. Luo et al.   DIABETOLOGIA

Nonalcoholic Fatty Liver Disease: Current Issues and Novel Treatment Approaches

(2013) Romina Lomonaco et al.   DRUGS

Mineralocorticoid receptor antagonists attenuate pulmonary inflammation and bleomycin-evoked fibrosis in rodent models

(2013) Gissela B Lieber et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome

(2013) Robert S. Rahimi et al.   NUTRITION IN CLINICAL PRACTICE

The relationship between oxidative stress and nonalcoholic fatty liver disease: Its effects on the development of nonalcoholic steatohepatitis

(2013) Fatma Ucar et al.   REDOX REPORT

Pathogenesis of hepatic steatosis: The link between hypercortisolism and non-alcoholic fatty liver disease

(2013) Giovanni Tarantino   WORLD JOURNAL OF GASTROENTEROLOGY

The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity

(2013) Finn Thomsen Nielsen et al.   BMC Nephrology

Contribution of glucocorticoid–mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction

(2012) Ayumu Hirata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophage Mineralocorticoid Receptor Signaling Plays a Key Role in Aldosterone-Independent Cardiac Fibrosis

(2012) Laura A. Bienvenu et al.   ENDOCRINOLOGY

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

(2012) Naga Chalasani et al.   GASTROENTEROLOGY

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Impaired renal function in morbid obese patients with nonalcoholic fatty liver disease

(2011) Mariana V. Machado et al.   LIVER INTERNATIONAL

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

Long-term mortality in nonalcoholic fatty liver disease: Is liver histology of any prognostic significance?

(2010) Paul Angulo   HEPATOLOGY

Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice

(2010) Michael G. Usher et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-alcoholic fatty liver disease and its association with obesity, insulin resistance and increased serum levels of C-reactive protein in Hispanics

(2010) Arnoldo Riquelme et al.   LIVER INTERNATIONAL

Pathology of nonalcoholic fatty liver disease

(2010) Elizabeth M. Brunt   Nature Reviews Gastroenterology & Hepatology

Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice

(2009) Ayumu Hirata et al.   CARDIOVASCULAR RESEARCH

A Comparison of the Aldosterone-blocking Agents Eplerenone and Spironolactone

(2009) Asterios Karagiannis et al.   CLINICAL CARDIOLOGY

c-Jun N-terminal Kinase-1 From Hematopoietic Cells Mediates Progression From Hepatic Steatosis to Steatohepatitis and Fibrosis in Mice

(2009) Yuzo Kodama et al.   GASTROENTEROLOGY

Overexpression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Hepatic and Visceral Adipose Tissue is Associated with Metabolic Disorders in Morbidly Obese Patients

(2009) René Baudrand et al.   OBESITY SURGERY

Mineralocorticoid Receptor Blockade Reverses Obesity-Related Changes in Expression of Adiponectin, Peroxisome Proliferator-Activated Receptor-γ, and Proinflammatory Adipokines

(2008) Christine Guo et al.   CIRCULATION