The TGF-β/SMAD pathway is an important mechanism for NK cell immune evasion in childhood B-acute lymphoblastic leukemia

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

(2014) A. Khoder et al.   BLOOD

A comparative study of the effects of inhibitory cytokines on human natural killer cells and the mechanistic features of transforming growth factor-beta

(2014) Hae mi Lee et al.   CELLULAR IMMUNOLOGY

c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells

(2014) Rosa Molfetta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of tumor cells and tumor microenvironment on NK-cell function

(2014) Massimo Vitale et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia

(2014) K. Stringaris et al.   HAEMATOLOGICA

Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells

(2014) G. F. Torelli et al.   HAEMATOLOGICA

The Incognito Journey of a Regulatory B Cell

(2014) Claudia Mauri et al.   IMMUNITY

TGF-  Utilizes SMAD3 to Inhibit CD16-Mediated IFN-  Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells

(2014) R. Trotta et al.   JOURNAL OF IMMUNOLOGY

Generation of Tumor Antigen-Specific T Cell Lines from Pediatric Patients with Acute Lymphoblastic Leukemia--Implications for Immunotherapy

(2013) G. Weber et al.   CLINICAL CANCER RESEARCH

Blocking transforming growth factor-β signaling pathway augments antitumor effect of adoptive NK-92 cell therapy

(2013) Bo Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neuroblastoma-Derived TGF- 1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells

(2013) R. Castriconi et al.   JOURNAL OF IMMUNOLOGY

Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications

(2012) Natalia Lapteva et al.   CYTOTHERAPY

Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group

(2012) Stephen P. Hunger et al.   JOURNAL OF CLINICAL ONCOLOGY

Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function

(2012) D J DiLillo et al.   LEUKEMIA

Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands

(2012) Laura Jardine et al.   LEUKEMIA & LYMPHOMA

Bispecific and Trispecific Killer Cell Engagers Directly Activate Human NK Cells through CD16 Signaling and Induce Cytotoxicity and Cytokine Production

(2012) M. K. Gleason et al.   MOLECULAR CANCER THERAPEUTICS

Tumor Induced Inactivation of Natural Killer Cell Cytotoxic Function; Implication in Growth, Expansion and Differentiation of Cancer Stem Cells

(2012) Anahid Jewett et al.   Journal of Cancer

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

IL-18 Induces PD-1-Dependent Immunosuppression in Cancer

(2011) M. Terme et al.   CANCER RESEARCH

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

(2011) Emilie Mamessier et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function

(2010) Moshe Elkabets et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Up on the tightrope: natural killer cell activation and inhibition

(2008) Lewis L Lanier   NATURE IMMUNOLOGY

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE