Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease
出版年份 2014 全文链接
标题
Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 24, Issue 6, Pages 1602-1616
出版商
Oxford University Press (OUP)
发表日期
2014-11-15
DOI
10.1093/hmg/ddu574
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Amyloid- signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
- (2013) M. E. Seward et al. JOURNAL OF CELL SCIENCE
- Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
- (2013) K. Sathasivam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration
- (2013) Michal Mielcarek et al. PLOS BIOLOGY
- Influence of Species Differences on the Neuropathology of Transgenic Huntington's Disease Animal Models
- (2012) Xiao-Jiang Li et al. Journal of Genetics and Genomics
- Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-β and prion peptides
- (2011) João P. Lopes et al. CELL CYCLE
- What have we learned from gene expression profiles in Huntington's disease?
- (2011) Tamara Seredenina et al. NEUROBIOLOGY OF DISEASE
- Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models
- (2011) Yuan-Ta Lin et al. PLoS One
- Cdk5: Multitasking between physiological and pathological conditions
- (2011) Joao P. Lopes et al. PROGRESS IN NEUROBIOLOGY
- A Two-Step Path to Inclusion Formation of Huntingtin Peptides Revealed by Number and Brightness Analysis
- (2010) Giulia Ossato et al. BIOPHYSICAL JOURNAL
- Polyglutamine shows a urea-like affinity for unfolded cytosolic protein
- (2010) Jeremy L. England et al. FEBS LETTERS
- Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease
- (2010) Christian Landles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Formation of Polyglutamine Inclusions in a Wide Range of Non-CNS Tissues in the HdhQ150 Knock-In Mouse Model of Huntington's Disease
- (2009) Hilary Moffitt et al. PLoS One
- Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human Cytomegalovirus Nuclear Egress
- (2009) Sofia Hamirally et al. PLoS Pathogens
- Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid
- (2008) Carme Pelegrí et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice
- (2008) A Jennifer Morton et al. NEUROBIOLOGY OF DISEASE
- Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
- (2008) Hyoung-gon Lee et al. NEUROCHEMISTRY INTERNATIONAL
- Time-lapse analysis of aggregate formation in an inducible PC12 cell model of Huntington's disease reveals time-dependent aggregate formation that transiently delays cell death
- (2007) B. Gong et al. BRAIN RESEARCH BULLETIN
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started