Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons

Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice

(2013) Linghua Qiu et al.   Molecular Neurodegeneration

Secreted VAPB/ALS8 Major Sperm Protein Domains Modulate Mitochondrial Localization and Morphology via Growth Cone Guidance Receptors

(2012) Sung Min Han et al.   DEVELOPMENTAL CELL

A mutation in VAPB that causes amyotrophic lateral sclerosis also causes a nuclear envelope defect

(2012) Duvinh Tran et al.   JOURNAL OF CELL SCIENCE

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

Accumulation of Wildtype and ALS-Linked Mutated VAPB Impairs Activity of the Proteasome

(2011) Anice Moumen et al.   PLoS One

The unfolded protein response in familial amyotrophic lateral sclerosis

(2010) L. Wang et al.   HUMAN MOLECULAR GENETICS

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology

(2010) E.L. Tudor et al.   NEUROSCIENCE

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

(2009) Elisa Fasana et al.   FASEB JOURNAL

Excitatory Actions of Ventral Root Stimulation During Network Activity Generated by the Disinhibited Neonatal Mouse Spinal Cord

(2009) Agnes Bonnot et al.   JOURNAL OF NEUROPHYSIOLOGY

Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

(2009) Xian Lin et al.   NEURON

A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity

(2009) Laskaro Zagoraiou et al.   NEURON

From ER to Eph Receptors: New Roles for VAP Fragments

(2008) Susan L. Ackerman et al.   CELL

The Amyotrophic Lateral Sclerosis 8 Protein VAPB Is Cleaved, Secreted, and Acts as a Ligand for Eph Receptors

(2008) Hiroshi Tsuda et al.   CELL

VAPB interacts with and modulates the activity of ATF6

(2008) C. Gkogkas et al.   HUMAN MOLECULAR GENETICS

ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB

(2008) Hiroaki Suzuki et al.   JOURNAL OF NEUROCHEMISTRY

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

(2007) Jayanth S. Chandran et al.   NEUROBIOLOGY OF DISEASE