Network-assisted analysis to prioritize GWAS results: principles, methods and perspectives
出版年份 2013 全文链接
标题
Network-assisted analysis to prioritize GWAS results: principles, methods and perspectives
作者
关键词
Obstructive Sleep Apnea, Differentially Express, Node Weight, GWAS Data, Gene Prioritization
出版物
HUMAN GENETICS
Volume 133, Issue 2, Pages 125-138
出版商
Springer Nature
发表日期
2013-10-12
DOI
10.1007/s00439-013-1377-1
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Network-Based Multiple Sclerosis Pathway Analysis with GWAS Data from 15,000 Cases and 30,000 Controls
- (2013) Sergio E. Baranzini et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Boosting signals in gene-based association studies via efficient SNP selection
- (2013) C. Wu et al. BRIEFINGS IN BIOINFORMATICS
- Association Signals Unveiled by a Comprehensive Gene Set Enrichment Analysis of Dental Caries Genome-Wide Association Studies
- (2013) Quan Wang et al. PLoS One
- Gene-Based Testing of Interactions in Association Studies of Quantitative Traits
- (2013) Li Ma et al. PLoS Genetics
- Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection
- (2012) Towfique Raj et al. AMERICAN JOURNAL OF HUMAN GENETICS
- An unbiased evaluation of gene prioritization tools
- (2012) Daniela Börnigen et al. BIOINFORMATICS
- PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis
- (2012) Sam Ng et al. BIOINFORMATICS
- Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes
- (2012) Inti Pedroso et al. BIOLOGICAL PSYCHIATRY
- A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke
- (2012) A. Arning et al. BLOOD
- Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer
- (2012) Peilin Jia et al. BMC Systems Biology
- Integration of biological networks and pathways with genetic association studies
- (2012) Yan V. Sun HUMAN GENETICS
- Patterns and rates of exonic de novo mutations in autism spectrum disorders
- (2012) Benjamin M. Neale et al. NATURE
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism
- (2012) Stephan J. Sanders et al. NATURE
- De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia
- (2012) Bin Xu et al. NATURE GENETICS
- Diverse types of genetic variation converge on functional gene networks involved in schizophrenia
- (2012) Sarah R Gilman et al. NATURE NEUROSCIENCE
- Rare and common variants: twenty arguments
- (2012) Greg Gibson NATURE REVIEWS GENETICS
- The TissueNet database of human tissue protein–protein interactions
- (2012) Ruth Barshir et al. NUCLEIC ACIDS RESEARCH
- Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments
- (2012) Luz García-Alonso et al. NUCLEIC ACIDS RESEARCH
- The BioGRID interaction database: 2013 update
- (2012) Andrew Chatr-aryamontri et al. NUCLEIC ACIDS RESEARCH
- Comparison of Pathway Analysis Approaches Using Lung Cancer GWAS Data Sets
- (2012) Gordon Fehringer et al. PLoS One
- Protein-Protein Interaction Analysis Highlights Additional Loci of Interest for Multiple Sclerosis
- (2012) Giammario Ragnedda et al. PLoS One
- Interactome mapping for analysis of complex phenotypes: Insights from benchmarking binary interaction assays
- (2012) Pascal Braun PROTEOMICS
- Pathway analysis of genomic data: concepts, methods, and prospects for future development
- (2012) Vijay K. Ramanan et al. TRENDS IN GENETICS
- Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation
- (2012) Jun Zhu et al. PLOS BIOLOGY
- Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia
- (2012) Peilin Jia et al. PLoS Computational Biology
- “Guilt by Association” Is the Exception Rather Than the Rule in Gene Networks
- (2012) Jesse Gillis et al. PLoS Computational Biology
- Networks of Neuronal Genes Affected by Common and Rare Variants in Autism Spectrum Disorders
- (2012) Eyal Ben-David et al. PLoS Genetics
- GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure
- (2011) Miao-Xin Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies
- (2011) Lily Wang et al. BIOINFORMATICS
- Characterizing genetic interactions in human disease association studies using statistical epistasis networks
- (2011) Ting Hu et al. BMC BIOINFORMATICS
- Interactome Networks and Human Disease
- (2011) Marc Vidal et al. CELL
- Protein Interaction-Based Genome-Wide Analysis of Incident Coronary Heart Disease
- (2011) Majken K. Jensen et al. Circulation-Cardiovascular Genetics
- Statistical analysis of rare sequence variants: an overview of collapsing methods
- (2011) Carmen Dering et al. GENETIC EPIDEMIOLOGY
- Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets
- (2011) Q. Xiong et al. GENOME RESEARCH
- Prioritizing candidate disease genes by network-based boosting of genome-wide association data
- (2011) I. Lee et al. GENOME RESEARCH
- Gene set analysis of genome-wide association studies: Methodological issues and perspectives
- (2011) Lily Wang et al. GENOMICS
- Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma
- (2011) Mingfeng Zhang et al. HUMAN GENETICS
- Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing
- (2011) Kathleen Askland et al. HUMAN GENETICS
- Pathway-based analysis of GWAS datasets: effective but caution required
- (2011) Peilin Jia et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia
- (2011) Peilin Jia et al. JOURNAL OF MEDICAL GENETICS
- Genome partitioning of genetic variation for complex traits using common SNPs
- (2011) Jian Yang et al. NATURE GENETICS
- Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses
- (2011) Sarah R. Gilman et al. NEURON
- A Systems Approach to the Biology of Mood Disorders through Network Analysis of Candidate Genes
- (2011) S. D. Detera-Wadleigh et al. PHARMACOPSYCHIATRY
- A Network-Based Approach to Prioritize Results from Genome-Wide Association Studies
- (2011) Nirmala Akula et al. PLoS One
- A New Methodology to Associate SNPs with Human Diseases According to Their Pathway Related Context
- (2011) Burcu Bakir-Gungor et al. PLoS One
- Pervasive Sharing of Genetic Effects in Autoimmune Disease
- (2011) Chris Cotsapas et al. PLoS Genetics
- Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
- (2011) Elizabeth J. Rossin et al. PLoS Genetics
- Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data
- (2010) Lin S. Chen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive Ability
- (2010) Dina Ruano et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application
- (2010) Rita M. Cantor et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Powerful SNP-Set Analysis for Case-Control Genome-wide Association Studies
- (2010) Michael C. Wu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Versatile Gene-Based Test for Genome-wide Association Studies
- (2010) Jimmy Z. Liu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM
- (2010) Charles J. Vaske et al. BIOINFORMATICS
- dmGWAS: dense module searching for genome-wide association studies in protein–protein interaction networks
- (2010) Peilin Jia et al. BIOINFORMATICS
- Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis
- (2010) Sergio E. Baranzini et al. BRAIN
- Identification of a gene module associated with BMD through the integration of network analysis and genome-wide association data
- (2010) Charles R Farber JOURNAL OF BONE AND MINERAL RESEARCH
- Hints of hidden heritability in GWAS
- (2010) Greg Gibson NATURE GENETICS
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Analysing biological pathways in genome-wide association studies
- (2010) Kai Wang et al. NATURE REVIEWS GENETICS
- Network medicine: a network-based approach to human disease
- (2010) Albert-László Barabási et al. NATURE REVIEWS GENETICS
- Common variants conferring risk of schizophrenia: A pathway analysis of GWAS data
- (2010) Peilin Jia et al. SCHIZOPHRENIA RESEARCH
- A human functional protein interaction network and its application to cancer data analysis
- (2010) Guanming Wu et al. GENOME BIOLOGY
- Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder
- (2009) Peter Holmans et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease
- (2009) Kai Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases–schizophrenia as a case
- (2009) Jingchun Sun et al. BIOINFORMATICS
- Comment on: Perry et al. (2009) Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach. Diabetes;58:1463-1467
- (2009) C. C. Elbers et al. DIABETES
- Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach
- (2009) J. R.B. Perry et al. DIABETES
- Gene and pathway-based second-wave analysis of genome-wide association studies
- (2009) Gang Peng et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
- (2009) S. E. Baranzini et al. HUMAN MOLECULAR GENETICS
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- KEGG for representation and analysis of molecular networks involving diseases and drugs
- (2009) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Network Analysis of Differential Expression for the Identification of Disease-Causing Genes
- (2009) Daniela Nitsch et al. PLoS One
- Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
- (2009) L. A. Hindorff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis
- (2009) Brett A. McKinney et al. PLoS Genetics
- Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
- (2009) Soumya Raychaudhuri et al. PLoS Genetics
- Walking the Interactome for Prioritization of Candidate Disease Genes
- (2008) Sebastian Köhler et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission
- (2008) Kathleen Askland et al. HUMAN GENETICS
- Genomewide association for schizophrenia in the CATIE study: results of stage 1
- (2008) P F Sullivan et al. MOLECULAR PSYCHIATRY
- Integrated network analysis platform for protein-protein interactions
- (2008) Jianmin Wu et al. NATURE METHODS
- A principal components regression approach to multilocus genetic association studies
- (2007) Kai Wang et al. GENETIC EPIDEMIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now