Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Minnelide reduces tumor burden in preclinical models of osteosarcoma

(2013) Sulagna Banerjee et al.   CANCER LETTERS

Triptolide-induced Cell Death in Pancreatic Cancer Is Mediated byO-GlcNAc Modification of Transcription Factor Sp1

(2013) Sulagna Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death

(2013) Zhiyu Chen et al.   Molecular Cancer

Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo

(2013) Ilona Rousalova et al.   PLoS One

Meeting the biologic challenge of colorectal metastases

(2012) Harold J. Wanebo et al.   CLINICAL & EXPERIMENTAL METASTASIS

Triptolide inhibits proliferation and invasion of malignant glioma cells

(2012) Haipeng Zhang et al.   JOURNAL OF NEURO-ONCOLOGY

Triptolide inhibits colon-rectal cancer cells proliferation by induction of G1 phase arrest through upregulation of p21

(2012) Juanjuan Liu et al.   PHYTOMEDICINE

A Preclinical Evaluation of Minnelide as a Therapeutic Agent Against Pancreatic Cancer

(2012) R. Chugh et al.   Science Translational Medicine

Prosurvival role of heat shock factor 1 in the pathogenesis of pancreatobiliary tumors

(2011) Vikas Dudeja et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic Pathways

(2010) Nameeta Mujumdar et al.   GASTROENTEROLOGY

Triptolide and TRAIL Combination Enhances Apoptosis in Cholangiocarcinoma

(2010) Kimberly A. Clawson et al.   JOURNAL OF SURGICAL RESEARCH

MAPKs Are Not Involved in Triptolide-Induced Cell Growth Inhibition and Apoptosis in Prostate Cancer Cell Lines with Different p53 Status

(2010) Wei Li et al.   PLANTA MEDICA

Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro

(2009) Andres I. Roig et al.   GASTROENTEROLOGY

Improved Overall Survival With Oxaliplatin, Fluorouracil, and Leucovorin As Adjuvant Treatment in Stage II or III Colon Cancer in the MOSAIC Trial

(2009) Thierry André et al.   JOURNAL OF CLINICAL ONCOLOGY

A Small-Molecule Triptolide Suppresses Angiogenesis and Invasion of Human Anaplastic Thyroid Carcinoma Cells via Down-Regulation of the Nuclear Factor- B Pathway

(2009) W. Zhu et al.   MOLECULAR PHARMACOLOGY

Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo

(2009) Mara B. Antonoff et al.   SURGERY

Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro

(2009) Fei Zhao et al.   TOXICOLOGY