Triptolide-induced Cell Death in Pancreatic Cancer Is Mediated byO-GlcNAc Modification of Transcription Factor Sp1

Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor–kappa B activity

(2013) Tara C.K. Krosch et al.   AMERICAN JOURNAL OF SURGERY

Minnelide reduces tumor burden in preclinical models of osteosarcoma

(2013) Sulagna Banerjee et al.   CANCER LETTERS

Critical Role ofO-Linked β-N-Acetylglucosamine Transferase in Prostate Cancer Invasion, Angiogenesis, and Metastasis

(2012) Thomas P. Lynch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MUC1c Regulates Cell Survival in Pancreatic Cancer by Preventing Lysosomal Permeabilization

(2012) Sulagna Banerjee et al.   PLoS One

A Preclinical Evaluation of Minnelide as a Therapeutic Agent Against Pancreatic Cancer

(2012) R. Chugh et al.   Science Translational Medicine

O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

(2011) Wenyi Mi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Gene expression of O-GlcNAc cycling enzymes in human breast cancers

(2011) Anna Krześlak et al.   CLINICAL AND EXPERIMENTAL MEDICINE

O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation

(2011) Qianqian Zhu et al.   MEDICAL ONCOLOGY

XPB, a subunit of TFIIH, is a target of the natural product triptolide

(2011) Denis V Titov et al.   Nature Chemical Biology

Modulation of transcription factor function by O-GlcNAc modification

(2010) Sabire Özcan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic Pathways

(2010) Nameeta Mujumdar et al.   GASTROENTEROLOGY

Inhibition of NFκB and Pancreatic Cancer Cell and Tumor Growth by Curcumin Is Dependent on Specificity Protein Down-regulation

(2010) Indira Jutooru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat Shock Protein 70 Inhibits Apoptosis in Cancer Cells Through Simultaneous and Independent Mechanisms

(2009) Vikas Dudeja et al.   GASTROENTEROLOGY

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA

(2009) S. Vispe et al.   MOLECULAR CANCER THERAPEUTICS

Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo

(2009) Mara B. Antonoff et al.   SURGERY

Sp1, a New Biomarker That Identifies a Subset of Aggressive Pancreatic Ductal Adenocarcinoma

(2008) N. Y. Jiang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION