Article
Environmental Sciences
Hedi Katre Kriit, Bertil Forsberg, Daniel Oudin Astrom, Anna Oudin
Summary: This study estimated that approximately 5% of annual dementia cases in Sweden could be attributed to PM2.5 exposure, leading to a substantial monetary burden. These findings highlight the importance of considering airborne toxic pollutants associated with dementia incidence in public health policy decisions.
ENVIRONMENTAL HEALTH
(2021)
Article
Green & Sustainable Science & Technology
Nur 'atiah Zaini, Ali Najah Ahmed, Lee Woen Ean, Ming Fai Chow, Marlinda Abdul Malek
Summary: Accurate air pollution forecasting is crucial for urban planning and health risk management. This study utilizes hybrid deep learning models to forecast PM2.5 concentration in Kuala Lumpur, Malaysia, and improves prediction accuracy through analyzing neighboring station data and optimizing model parameters.
JOURNAL OF CLEANER PRODUCTION
(2023)
Review
Environmental Sciences
Zhenjie Wang, Mengmeng Xu, Yanhua Wang, Ting Wang, Nan Wu, Wenjing Zheng, Huawei Duan
Summary: The study investigated the impact of PM exposure on surfactant proteins, finding a significant decrease in circulating SP-D and an increase in serum SP-A among smokers. These results suggest that circulating surfactant proteins may serve as biomarkers for respiratory injury caused by air particulate matter.
Article
Engineering, Environmental
Aaron van Donkelaar, Melanie S. Hammer, Liam Bindle, Michael Brauer, Jeffery R. Brook, Michael J. Garay, N. Christina Hsu, Olga Kalashnikova, Ralph A. Kahn, Colin Lee, Robert C. Levy, Alexei Lyapustin, Andrew M. Sayer, Randall Martin
Summary: This study developed a methodology for monthly PM2.5 estimates and uncertainties using satellite retrievals, chemical transport modeling, and ground-based measurements. Findings show higher winter PM2.5 concentrations in many densely populated regions, with South Asia and East Asia having particularly high levels, although East Asia showed a decreasing trend in PM2.5 concentrations over the period studied.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Nelson Gouveia, Josiah L. Kephart, Iryna Dronova, Leslie McClure, Jose Tapia Granados, Ricardo Morales Betancourt, Andrea Cortinez O'Ryan, Jose Luis Texcalac-Sangrador, Kevin Martinez-Folgar, Daniel Rodriguez, Ana Diez-Roux
Summary: The study found that a significant proportion of the population in Latin American cities live in areas with air pollution levels above WHO standards. Larger cities, higher GDP, higher motorization rate, and congestion tend to have higher PM2.5 levels. On the other hand, areas with higher population density tend to have lower levels of PM2.5.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Benjamin Bowe, Andrew K. Gibson, Yan Xie, Yan Yan, Aaron van Donkelaar, Randall V. Martin, Ziyad Al-Aly
Summary: The study found a correlation between PM2.5 and the risks of weight gain and obesity, especially at PM2.5 concentrations below the national standard. Results were consistent across different sensitivity analyses, suggesting that PM2.5 air pollution may contribute to obesity and weight gain.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2021)
Article
Environmental Sciences
Ying-Ying Meng, Yu Yu, Mohammad Z. Al-Hamdan, Miriam E. Marlier, Joseph L. Wilkins, Diane Garcia-Gonzales, Xiao Chen, Michael Jerrett
Summary: This study investigated the impact of short-term exposure to particulate matter (PM2.5) on work loss due to sickness. The findings showed a positive association between short-term ambient PM2.5 exposure and work loss, which was stronger among individuals with higher exposure to wildfire smoke. This suggests the need for further strengthening of PM2.5 standards in California to protect public health.
ENVIRONMENT INTERNATIONAL
(2023)
Review
Environmental Sciences
Leen Rasking, Kenneth Vanbrabant, Hannelore Bove, Michelle Plusquin, Katrien De Vusser, Harry A. Roels, Tim S. Nawrot
Summary: This review summarizes the relevant knowledge on the effects of ambient PM2.5 on kidney function in adults. Most studies showed that PM2.5 exposure worsened kidney outcomes, but contradictory results were also found. The included studies have limitations, and further investigations are needed to determine the extent of PM2.5's adverse effects on the kidney.
ENVIRONMENTAL HEALTH
(2022)
Review
Toxicology
Jinjuta Panumasvivat, Wasana Pratchayasakul, Ratana Sapbamrer, Nipon Chattipakorn, Siriporn C. Chattipakorn
Summary: Over the past 30 years, environmental pollution, particularly ambient particulate matter, has significantly affected human health and longevity. Recent studies have demonstrated that exposure to particulate matter directly leads to respiratory system damage, including free radical peroxidation, intercellular calcium regulation imbalance, and inflammation, resulting in respiratory diseases. The respiratory microbiome plays a crucial role in lung immunity and development, and previous research has confirmed its association with chronic respiratory diseases. However, there is still limited knowledge about the changes in the respiratory microbiome in relation to particulate matter exposure and respiratory diseases. Therefore, this review aims to summarize and discuss the existing evidence, from in vivo to clinical studies, regarding the effect of particulate matter exposure on the respiratory microbiome and respiratory diseases.
ARCHIVES OF TOXICOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Amy McCarron, Sean Semple, Christine F. Braban, Colin Gillespie, Vivien Swanson, Heather D. Price
Summary: This study investigates the acute effects of personal exposure to PM2.5 on self-reported asthma-related health. The results show individual exposure to PM2.5 varies across microenvironments and is associated with asthma symptoms. However, there is no significant association between exposure and reliever inhaler use.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Geriatrics & Gerontology
Kevin J. Sullivan, Xinhui Ran, Fan Wu, Chung-Chou H. Chang, Ravi Sharma, Erin Jacobsen, Sarah Berman, Beth E. Snitz, Akira Sekikawa, Evelyn O. Talbott, Mary Ganguli
Summary: This study examined the association between ambient PM2.5 levels and the risk of incident MCI and dementia in an older population, finding that higher estimated PM2.5 levels were associated with increased risk of both conditions, particularly with longer-term exposure.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Environmental Sciences
Rashmi Choudhary, Amit Agarwal
Summary: Incorporating high spatiotemporal resolution improves prediction accuracy. This study identifies the most suitable spatial resolution using hexagonal tessellations. A hybrid deep-learning-based prediction model is developed and compared for different grid sizes. The results show that the 3 km grid performs best in terms of data aggregation and prediction accuracy. Future work can include mobile monitoring data to further enhance the models' accuracy.
ATMOSPHERIC POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Junhui Wu, Yaohua Tian, Yao Wu, Zijing Wang, Yiqun Wu, Tao Wu, Xueying Qin, Mengying Wang, Xiaowen Wang, Jiating Wang, Yonghua Hu
Summary: The study revealed a significant association between PM2.5 levels and outpatient visits for venous thromboembolism in Beijing, with a more pronounced relationship observed during the warm season. Adjusting for temperature at various time lags should be considered when investigating seasonal associations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
Kohei Hasegawa, Teruomi Tsukahara, Tetsuo Nomiyama
Summary: There is limited research on the relationship between low levels of daily fine particulate matter (PM2.5) exposure and morbidity or mortality in non-western countries, especially at PM2.5 concentrations below 15 μg/m3, the latest WHO AQG value. This study in Japan found that even at low concentrations, an increase in PM2.5 was associated with an increase in cardiorespiratory hospital admissions. The findings suggest that the current WHO guideline value may be insufficient for protecting public health.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Public, Environmental & Occupational Health
Jingyi Qin, Wei Xia, Gaodao Liang, Shunqing Xu, Xiuge Zhao, Danlu Wang, Xiaojie Sun, Yuanyuan Li, Hongxiu Liu
Summary: Exposure to high levels of PM2.5 may lead to decreased insulin levels and increased oxidized LDL levels, with females, overweight, and obese individuals being more susceptible to these effects.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2021)
Article
Environmental Sciences
Arash Derakhshan, Elise M. Philips, Akhgar Ghassabian, Susana Santos, Alexandros G. Asimakopoulos, Kurunthachalam Kannan, Andreas Kortenkamp, Vincent W. V. Jaddoe, Leonardo Trasande, Robin P. Peeters, Tim I. M. Korevaar
Summary: Exposure to bisphenols during pregnancy may interfere with maternal thyroid function and affect the thyroid system in offspring. There were associations between BPA and BPS concentrations with maternal thyroid function, with late pregnancy BPA exposure linked to higher TSH in female newborns and higher FT4 during childhood in males.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Endocrinology & Metabolism
Carolina C. V. Silva, Vincent W. V. Jaddoe, Chalana M. Sol, Hanan El Marroun, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Leonardo Trasande, Susana Santos
Summary: The study found that higher levels of DNOP metabolites at 6 years old were associated with an increased risk of overweight and adverse cardiovascular profile at both 6 and 10 years. On the other hand, higher total bisphenols and bisphenol A concentrations were linked to a decrease in BMI from 6 to 10 years.
Article
Multidisciplinary Sciences
Anne L. Dunlop, Alicynne Glazier Essalmi, Lyndsay Alvalos, Carrie Breton, Carlos A. Camargo, Whitney J. Cowell, Dana Dabelea, Stephen R. Dager, Cristiane Duarte, Amy Elliott, Raina Fichorova, James Gern, Monique M. Hedderson, Elizabeth Hom Thepaksorn, Kathi Huddleston, Margaret R. Karagas, Ken Kleinman, Leslie Leve, Ximin Li, Yijun Li, Augusto Litonjua, Yunin LudenaRodriguez, Juliette C. Madan, Julio Mateus Nino, Cynthia McEvoy, Thomas G. O'Connor, Amy M. Padula, Nigel Paneth, Frederica Perera, Sheela Sathyanarayana, Rebecca J. Schmidt, Robert T. Schultz, Jessica Snowden, Joseph B. Stanford, Leonardo Trasande, Heather E. Volk, William Wheaton, Rosalind J. Wright, Monica McGrath
Summary: This study examined the impact of maternal education and neighborhood SES markers on gestational age at birth, finding that higher maternal education was associated with a decreased odds of preterm birth, while lower education levels were linked to an increased odds of early term birth. Variations in these associations were observed among different racial/ethnic groups and across different regions in the United States.
Article
Environmental Sciences
Hongxiu Liu, Anna Maria Campana, Yuyan Wang, Kurunthachalam Kannan, Mengling Liu, Hongkai Zhu, Shilpi Mehta-Lee, Sara G. Brubaker, Linda G. Kahn, Leonardo Trasande, Akhgar Ghassabian
Summary: The study found that pregnant women in NYC had lower levels of OP pesticide metabolites than pregnant populations in Europe, Asia, and other regions in the U.S. Lower pre-pregnancy body mass index, being Asian, employed, and single were associated with higher DAP metabolite concentrations, while fruit and grain intakes were associated with higher Sigma DM, Sigma DE, and Sigma DAP levels.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande, Susana Santos
Summary: Higher maternal bisphenol S urine concentrations, especially in the first trimester, seem to be associated with larger fetal head circumference, higher weight, and a lower risk of being small size for gestational age at birth. Other bisphenols were not consistently associated with fetal growth outcomes.
ENVIRONMENTAL HEALTH
(2021)
Article
Endocrinology & Metabolism
Melanie H. Jacobson, Cheryl R. Stein, Mengling Liu, Marra G. Ackerman, Jennifer K. Blakemore, Sara E. Long, Graziano Pinna, Raquel Romay-Tallon, Kurunthachalam Kannan, Hongkai Zhu, Leonardo Trasande
Summary: The study investigated the associations between urinary bisphenols and phthalates in early and midpregnancy with serum hormone concentrations and postpartum depression symptoms. The results suggested that certain phthalates were related to lower progesterone levels and increased odds of PPD, indicating a potential influence of endocrine disrupting chemicals on hormonal shifts during pregnancy and PPD.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Environmental Sciences
Sara E. Long, Linda G. Kahn, Leonardo Trasande, Melanie H. Jacobson
Summary: This study investigated the association between phthalate metabolites and sex hormone concentrations in women, finding that DEHP was associated with lower estradiol and bioavailable testosterone concentrations in postmenopausal women, while DINCH was associated with higher free testosterone, bioavailable testosterone, and free androgen index. DEHTP was associated with a higher testosterone-to-estradiol ratio. Further research is needed to explore the safety of these chemicals.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Nutrition & Dietetics
Andrea L. Deierlein, Akhgar Ghassabian, Linda G. Kahn, Yelena Afanasyeva, Shilpi S. Mehta-Lee, Sara G. Brubaker, Leonardo Trasande
Summary: The study assessed the diet quality of pregnant women before and during pregnancy and found that Hispanic women had higher total HEI-2015 scores compared to non-Hispanic White women. Factors such as younger age, higher parity, single status, pre-pregnancy obesity, smoking, and other health behaviors were associated with lower total HEI-2015 scores. This highlights the need for continued nutritional counseling for preconception and prenatal care.
FRONTIERS IN NUTRITION
(2021)
Article
Environmental Sciences
Susana Santos, Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande
Summary: Exposure to phthalates during pregnancy may lead to fetal growth restriction and preterm birth. Different trimester-specific exposures to phthalates may have varying effects on fetal growth and birth outcomes.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Melanie H. Jacobson, Yinxiang Wu, Mengling Liu, Kurunthachalam Kannan, Adela Jing Li, Morgan Robinson, Bradley A. Warady, Susan Furth, Howard Trachtman, Leonardo Trasande
Summary: The study found that urinary DAP metabolites were positively associated with renal injury biomarkers KIM-1 and 8-OHdG, as well as eGFR in children with CKD. These findings provide preliminary evidence that DAP metabolites in urine are related to subclinical kidney injury in children with CKD, which may indicate future clinical events.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Leonardo Trasande, Buyun Liu, Wei Bao
Summary: The study found that high-molecular weight phthalate metabolites, especially DEHP, were associated with increased mortality. Extrapolating to the 55-64 year old American population, the estimated attributable deaths related to phthalate exposure exceeded 90,000, with lost economic productivity in the billions of dollars.
ENVIRONMENTAL POLLUTION
(2022)
Article
Pediatrics
Sheryl L. Rifas-Shiman, L. Charles Bailey, Doug Lunsford, Matthew F. Daley, Ihuoma Eneli, Jonathan Finkelstein, William Heerman, Casie E. Horgan, Daniel S. Hsia, Melanie Jay, Goutham Rao, Juliane S. Reynolds, Jessica L. Sturtevant, Sengwee Toh, Leonardo Trasande, Jessica Young, Debby Lin, Christopher B. Forrest, Jason P. Block
Summary: The study found that antibiotic use before 24 months of age was associated with slightly higher BMI-z at 10 years old, but did not have a significant impact on the likelihood of overweight or obesity.
ACADEMIC PEDIATRICS
(2021)
Article
Pediatrics
Lauren Z. Foster, Joshua Beiner, Carol Duh-Leong, Kira Mascho, Victoria Giordani, Michael L. Rinke, Leonardo Trasande, Ethan Wiener, Rebecca E. Rosenberg
PEDIATRIC QUALITY & SAFETY
(2020)
Article
Environmental Sciences
Chalana M. Sol, Susana Santos, Liesbeth Duijts, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande
ENVIRONMENT INTERNATIONAL
(2020)
Article
Endocrinology & Metabolism
Linda G. Kahn, Claire Philippat, Shoji F. Nakayama, Remy Slama, Leonardo Trasande
LANCET DIABETES & ENDOCRINOLOGY
(2020)