Green synthesis of Solanum xanthocarpum mediated selenium nanoparticles and its biomedical applications

---

作者

Azmathullah Rahmathullah¹

1. Chettinad Academy of Research and Education

会议/活动

International Conference on Current trends on Biomedical Research, September 2022 (虚拟会议)

海报摘要

Nanoparticles serve to reduce toxicity, enhance bioactivity and improve targeting. Selenium nanopartciles (SeNPs) are explored because of its unique characteristics and various known therapeutic benefits such antimicrobial activity, lower cytotoxic effects, antioxidants activities and reducing risk of cancer, and anti inflammatory activity using albumin denaturation assay. In this study, Solanum xanthocarpum mediated Selenium nanoparticles which has more antimicrobial activity against harmful pathogens and lowered toxic effects and potent anti inflammatory activity and antioxidants activities. Solanum xanthocarpum mediated Selenium nanoparticles were evaluated for its antimicrobial activity and cytotoxic activity using brine shrimp lethality assay. The anti-inflammatory activity is observed using albumin denaturation assay and antioxidant activity evaluated using DPPH assay. These Solanum xanthocarpum stabilized selenium nanoparticle formulations were demonstrated to have biocompatibility, strong potential demonstrated to have biocompatibility, as well as strong potential for application in the fields of medicine and food.

关键词

Solanum xanthocarpum, Cytotoxicity, Antimicrobial, Nanoparticles, Selenium particles, Anti-inflammatory

研究领域

Pharmacy and Pharmacology, Medicine, Nanoengineering, Genetics

参考文献

暂无数据

基金

暂无数据

补充材料

暂无数据

附加信息

利益冲突

No competing interests were disclosed.

数据可用性声明

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

知识共享许可协议

Copyright © 2022 Rahmathullah. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.