Article
Oncology
R. Tyler Hillman, Maria D. Iniesta, Qiuling Shi, Tina Suki, Tsun Chen, Katherine Cain, Loretta Williams, Xin Shelley Wang, Jolyn S. Taylor, Gabriel Mena, Javier Lasala, Pedro T. Ramirez, Larissa A. Meyer
Summary: The study found that implementing restrictive post-operative opioid prescribing did not result in differences in longitudinal symptom burden among women undergoing minimally invasive gynecologic surgery.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Oncology
Stephanie Alimena, Lauren Philp, Endel John Orav, Mackenzie W. Sullivan, Marcela Del Carmen, Annekathryn Goodman, Whitfield B. Growdon, Amy Bregar, Eric Eisenhauer, Rachel Clark Sisodia
Summary: While no obvious memory issues were discovered with serial administration of patient-reported outcome measures, rates of adverse emotional symptoms such as depression, tension, and worry decreased after chemotherapy. Chemotherapy can have some impact on patients' social lives. Further research with a larger cohort is needed to explore the phenomenon of chemotherapy-related cognitive impairment.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Oncology
Victoria Huynh, Kathryn Colborn, Shelby Smith, Levi N. Bonnell, Gretchen Ahrendt, Nicole Christian, Simon Kim, Dan D. Matlock, Clara Lee, Sarah E. Tevis
Summary: This study aimed to compare longitudinal patient-reported outcomes between breast cancer patients undergoing lumpectomy and mastectomy, finding that mastectomy patients experienced significantly greater decreases in breast satisfaction, psychosocial well-being, and sexual well-being over time compared with lumpectomy patients, with lumpectomy patients more likely to return to baseline scores at 3 and 6 months postoperatively. Understanding these differences can inform early intervention strategies to prevent long-term morbidities.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Orthopedics
Brandon A. Ramo, Teresa L. Collins-Jones, David Thornberg, Lydia Klinkerman, Karl Rathjen, Chan-Hee Jo
Summary: This study aimed to investigate the prevalence of pain catastrophizing in patients with adolescent idiopathic scoliosis (AIS) and its relationship with preoperative and postoperative self-reported outcomes. The study found that pain catastrophizing was associated with lower self-reported scores, but patients experienced improvement in health after surgery.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Obstetrics & Gynecology
Ainhoa Madariaga, Gita Bhat, Michelle K. Wilson, Xuan Li, Sunu Cyriac, Valerie Bowering, Wendy Hunt, David Gutierrez, Luisa Bonilla, Lawrence Kasherman, Michelle McMullen, Lisa Wang, Sangeet Ghai, Neesha C. Dhani, Amit M. Oza, Stephanie Lheureux
Summary: This study prospectively assessed the impact of research biopsies on the quality of life in patients with gynecologic cancer, as well as patient-reported outcomes and factors associated with willingness to undergo sequential biopsies. Results showed that research biopsies were generally well accepted, with most patients (83%) willing to undergo serial biopsies if necessary. Addressing modifiable psychosocial aspects of the procedure may improve the experience with research biopsies for patients with gynecologic cancers.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Oncology
Rachel C. Sisodia, Stephanie Alimena, Winslow Ferris, Aashna Saini, Lauren Philp, Mackenzie Sullivan, Katelyn Dorney, Amy Bregar, Eric Eisenhauer, Annekathryn Goodman, Whitfield Growdon, Harrison Hubbell, Marcela del Carmen
Summary: This study prospectively collected and described disease-specific patient reported outcomes (PROs) in non-trial population of women with gynecologic malignancy. The study found that quality of life scores in the clinic population were lower than published data, indicating caution should be used when extrapolating quality of life data from clinical trials to counseling and decision making around routine patient populations.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Health Care Sciences & Services
Alexander Chern, Rahul K. Sharma, Maeher R. Grewal, Justin S. Golub
Summary: The study found that patients highly value minimizing pain and numbness after ear surgery, nearly as much as achieving a good hearing outcome. These patient-centric outcomes are crucial in justifying the use of TEES as a minimally invasive approach.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Gastroenterology & Hepatology
John E. Pandolfino, Dustin A. Carlson, Josie McGarva, Peter J. Kahrilas, Michael Vaezi, David Katzka, Tiffany H. Taft
Summary: The study developed a new Achalasia Patient-Reported Outcomes (APRO) Questionnaire, identified three subscales through investigation of patients with normal motility and achalasia, and found that symptom anxiety and hypervigilance moderate the relationship between APRO and quality of life.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Cardiac & Cardiovascular Systems
Adrienne H. Kovacs, Gerald Lebovic, Stavroula Raptis, Samuel Blais, Christopher A. Caldarone, Nagib Dahdah, Frederic Dallaire, Christian Drolet, Jasmine Grewal, Camille L. Hancock Friesen, Edward Hickey, Gauri Rani Karur, Paul Khairy, Benedetta Leonardi, Michelle Keir, Brian W. McCrindle, Syed Najaf Nadeem, Ming-Yen Ng, Ashish H. Shah, Edythe B. Tham, Judith Therrien, Andrew E. Warren, Isabelle F. Vonder Muhll, Alexander Van de Bruaene, Kenichiro Yamamura, Michael E. Farkouh, Rachel M. Wald
Summary: This study explored the relationship between pulmonary regurgitation and quality of life and health status in adults with Tetralogy of Fallot (TOF), and found that with advancing age, patients reported more problems in mobility and pain or discomfort. Factors associated with superior patient-reported outcomes include race, syndrome, employment, and left ventricular function, while being asymptomatic was found to have the greatest impact on quality of life and health status.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Surgery
Ali Aminian, Sangeeta R. Kashyap, Kathy E. Wolski, Stacy A. Brethauer, John P. Kirwan, Steven E. Nissen, Deepak L. Bhatt, Philip R. Schauer
Summary: This study found that metabolic surgery in patients with T2DM is associated with long-term favorable changes in certain patient-reported outcomes compared with intensive medical therapy, particularly in physical health and diabetes-related domains. The effects on psychosocial well-being were similar among the study groups.
Article
Oncology
Kelley C. Wood, Jessica Bertram, Tiffany Kendig, Mary Hidde, Aliza Leiser, Alexandre Buckley de Meritens, Mackenzi Pergolotti
Summary: This study reviewed the rehabilitation records of women with gynecologic cancer who received physical and occupational therapy and found that these interventions were acceptable and improved patient-reported outcomes.
SUPPORTIVE CARE IN CANCER
(2022)
Review
Cardiac & Cardiovascular Systems
Ruth Masterson Creber, Cristiano Spadaccio, Arnaldo Dimagli, Annie Myers, Brittany Taylor, Stephen Fremes
Summary: Patient-reported outcomes (PROs) offer a global perspective of a person's health status and are categorized into global, mental, physical, and social health domains. Challenges in using PROs in cardiac clinical trials include long-term measurement, inconsistency in outcome measures, and lack of measurement across multiple domains. Opportunities for advancement include utilizing consumer health informatics tools to measure PROs and quantifying minimal clinically important differences.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Oncology
Jennifer L. Baker, Don S. Dizon, Cachet M. Wenziger, Elani Streja, Carlie K. Thompson, Minna K. Lee, Maggie L. DiNome, Deanna J. Attai
Summary: The majority of patients who choose mastectomy alone do so for quicker recovery and to avoid foreign body placement. Patients with lower satisfaction are more likely to lack support from their surgeons, have a higher BMI, or undergo unilateral procedures. Higher satisfaction is associated with receiving adequate information about surgical options and having a specialized breast surgery practice.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Onkar V. Khullar, Jane W. Wei, Kaustabh Wagh, Jose N. Binongo, Allan Pickens, Manu S. Sancheti, Seth D. Force, Theresa W. Gillespie, Felix G. Fernandez
Summary: This study aimed to determine which clinical factors predict differences in quality of life (QOL) among patients undergoing minimally invasive lung cancer surgery. The research found that lower diffusing capacity of the lungs for carbon monoxide (DLCO) was associated with significant decreases in QOL after surgery, suggesting DLCO could help identify patients with greater decline in QOL post-surgery.
ANNALS OF THORACIC SURGERY
(2021)
Article
Oncology
Myung-Kyung Lee, Jihyun Oh
Summary: Exercise can have a synergistic effect on improving health-related quality of life (HRQOL) and depression in patients with gastric cancer, by indirectly positively affecting depression and directly influencing HRQOL.
Article
Oncology
Dimitrios Nasioudis, Stefan Gysler, Nawar Latif, Lory Cory, Robert L. Giuntoli II, Sarah H. Kim, Fiona Simpkins, Lainie Martin, Emily M. Ko
Summary: The prevalence of ERBB2 gene amplification was investigated among patients with gynecologic malignancies. The study found that ERBB2 amplification is frequently encountered in uterine serous carcinoma and mucinous ovarian carcinoma, but less common in endometrioid endometrial carcinoma.
GYNECOLOGIC ONCOLOGY
(2024)