Mucosal CXCR4+IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14 macrophage activation

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

(2011) Falk Hiepe et al.   Nature Reviews Rheumatology

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis

(2010) S. Hosomi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Genetic predictors of medically refractory ulcerative colitis

(2010) Talin Haritunians et al.   INFLAMMATORY BOWEL DISEASES

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells

(2010) Matthias Lochner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

CXCR3, Inflammation, and Autoimmune Diseases

(2009) Stéphanie Lacotte et al.   Annals of the New York Academy of Sciences

An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

(2009) M. Jourdan et al.   BLOOD

Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells

(2009) David Q. Shih et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An FcRn-Dependent Role for Anti-flagellin Immunoglobulin G in Pathogenesis of Colitis in Mice

(2009) Kanna Kobayashi et al.   GASTROENTEROLOGY

CXCL12 Is a constitutive and inflammatory chemokine in the intestinal immune system

(2009) Iris Dotan et al.   INFLAMMATORY BOWEL DISEASES

TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohnʼs disease

(2009) Nobuhiko Kamada et al.   INFLAMMATORY BOWEL DISEASES

CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus

(2009) A. Wang et al.   JOURNAL OF IMMUNOLOGY

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

(2009) Kouichi Asano et al.   NATURE GENETICS

Pathological Expression of CXCL12 at the Blood-Brain Barrier Correlates with Severity of Multiple Sclerosis

(2008) Erin E. McCandless et al.   AMERICAN JOURNAL OF PATHOLOGY

TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation

(2008) Hidetoshi Takedatsu et al.   GASTROENTEROLOGY

Blockade of CXCL12/CXCR4 Axis Ameliorates Murine Experimental Colitis

(2008) S. Mikami et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Matrix metalloproteinase-3 production by gut IgG plasma cells in chronic inflammatory bowel disease

(2007) John N. Gordon et al.   INFLAMMATORY BOWEL DISEASES