A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

The Yin and Yang of Immunomodulatory Biologics: Assessing the Delicate Balance between Benefit and Risk

(2012) Dimitry M. Danilenko et al.   TOXICOLOGIC PATHOLOGY

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes

(2011) EG Stefanich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Infliximab or Cyclosporine as Rescue Therapy in Hospitalized Patients with Steroid-Refractory Ulcerative Colitis: A Retrospective Observational Study

(2011) Mats Sjöberg et al.   INFLAMMATORY BOWEL DISEASES

Assessing the Role of CD103 in Immunity to an Intestinal Helminth Parasite

(2011) Sarah C. Mullaly et al.   PLoS One

CD103 Deficiency Prevents Graft-versus-Host Disease but Spares Graft-versus-Tumor Effects Mediated by Alloreactive CD8 T Cells

(2011) Kechang Liu et al.   PLoS One

Targeting leukocyte migration and adhesion in Crohn’s disease and ulcerative colitis

(2011) Saskia Thomas et al.   INFLAMMOPHARMACOLOGY

Natalizumab and Progressive Multifocal Leukoencephalopathy

(2010) Clemens Warnke et al.   ARCHIVES OF NEUROLOGY

HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort

(2010) Suzanne van Sommeren et al.   INFLAMMATORY BOWEL DISEASES

A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation

(2010) Marlon R. Schneider et al.   PLoS One

Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody

(2009) N Pullen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of β7 Integrins in Intestinal Lymphocyte Homing and Retention

(2009) G. Gorfu et al.   CURRENT MOLECULAR MEDICINE

861 Safety and Efficacy of Pf-00547,659, a Fully Human Anti-MAdCAM Antibody, in Ulcerative Colitis. Results of a First in Human Study

(2009) Severine Vermeire et al.   GASTROENTEROLOGY

Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn's disease

(2009) A. M. Muise et al.   GUT

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Treatment of Active Crohn's Disease With MLN0002, a Humanized Antibody to the α4β7 Integrin

(2008) Brian G. Feagan et al.   Clinical Gastroenterology and Hepatology

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE