Article
Endocrinology & Metabolism
In-Ho Jung, Seonah Choi, Cheol Ryong Ku, Sang-Guk Lee, Eun Jig Lee, Sun Ho Kim, Eui Hyun Kim
Summary: This study evaluated the reliability of IGF-1 levels as an alternative for disease monitoring after surgical treatment of acromegaly. The results showed that IGF-1 levels can serve as a reliable alternative to OGTT and play a valuable role in monitoring acromegaly status.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Endocrinology & Metabolism
Mengyang Li
Summary: The GH/IGF system plays a role in growth regulation in the body. By studying the basal chordate amphioxus, it was discovered that most members of the GH/IGF system are present in amphioxus, providing strong evidence for the origin of this system in amphioxus.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yang Xu, Chang Yong Han, Mi Jung Park, Myung Chan Gye
Summary: This study investigated the mechanism of precocious sexual maturation following prepubertal rhGH therapy. The results showed that rhGH can promote gonadal maturation by activating the steroidogenic pathway of LCs and increasing testicular IGF1 levels.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)
Article
Psychiatry
Naomichi Okamoto, Koji Yoshino, Shogo Kitagawa, Rintaro Fujii, Shinsuke Hamada, Atsuko Ikenouchi, Yuki Konishi, Nobuhisa Ueda, Yoshinori Eto, Yasunari Tsutsumi, Reiji Yoshimura
Summary: This study found no significant difference in serum IGF-1 levels between patients with chronic schizophrenia and healthy controls. Serum IGF-1 levels were significantly negatively correlated with PANSS total and general scores, and were associated with patient age.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Layla Damen, Melitza S. M. Elizabeth, Stephany H. Donze, Sjoerd A. A. van den Berg, Laura C. G. de Graaff, Anita C. S. Hokken-Koelega
Summary: In children with Prader-Willi syndrome receiving GH treatment, high immunoreactive IGF-I levels are often observed, while free IGF-I levels are low, indicating a significant discrepancy between the two.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Genetics & Heredity
Rui-Lin Xie, Rui Liang, Yuan-Yuan Luo, Zhuo-Hao Ruan, Yi-Fu Li, Wen-Sheng Liu
Summary: This study investigates the effects of growth hormone changes on the genes and regulatory roles of the turtle. The results show that the injection of recombinant human growth hormone promotes the growth of the turtle by affecting the expression of SS, GHR, and IGF-1 genes.
Review
Endocrinology & Metabolism
Laura E. Dichtel, Jose Cordoba-Chacon, Rhonda D. Kineman
Summary: This article summarizes the high prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with obesity and its progression to nonalcoholic steatohepatitis (NASH). Understanding the etiology of NAFLD is clinically relevant as it is an independent risk factor for diabetes and cardiovascular disease. The potential role of growth hormone and insulin-like growth factor 1 in regulating hepatic steatosis, inflammation, and fibrosis is discussed.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Christa C. van Bunderen, Rick I. Meijer, Paul Lips, Mark H. Kramer, Erik H. Serne, Madeleine L. Drent
Summary: The study found that increasing IGF-1 levels had a beneficial effect on body composition but was detrimental to insulin resistance. At the same time, the contribution of the neurogenic vasomotion domain also increased.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Chemistry, Medicinal
Fatemeh Meshkini, Nahid Ramezani-Jolfaie, Saman Sargazi, Cain C. T. Clark, Sepideh Soltani
Summary: A systematic review of the effects of lycopene on circulating IGF-1 and IGFBPs in adults found no consistent modifying effect of lycopene supplementation on IGF-1 and IGFBP levels. More research is needed to explore the effect of lycopene on the IGF-1 system.
PHYTOTHERAPY RESEARCH
(2022)
Article
Endocrinology & Metabolism
Ioannis Ilias, Aristidis Diamantopoulos, Efthymia Botoula, Nikolaos Athanasiou, Alexandros Zacharis, Stamatios Tsipilis, Edison Jahaj, Alice G. Vassiliou, Dimitra A. Vassiliadi, Anastasia Kotanidou, Stylianos Tsagarakis, Ioanna Dimopoulou
Summary: The study aimed to measure IGF1 and GH in critically and non-critically ill Covid-19 patients. Results showed that IGF-1 levels were higher in survivors compared to non-survivors, suggesting a potential association between low IGF1 and poor outcomes in Covid-19 patients.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yoshifumi Horie, Kensuke Mitsunaga, Chee Kong Yap
Summary: Pyriproxyfen, an agricultural pesticide, was found to have a lethal effect on zebrafish in a concentration-dependent manner. The study also revealed that pyriproxyfen disrupts thyroid hormone activity in zebrafish and inhibits their growth by suppressing the expression of growth hormone.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Qian Xin, Victoria Anthony Uyanga, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Haifang Li, Yunlei Zhou, Hai Lin
Summary: The decrease in serum and follicular IGF1 concentration is associated with the reduced egg production of aged laying hens. This study provides novel insights into the endocrine changes in aged hens with different egg production rates.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Kangkang Chen, Xiaoyi Dou, Jai Hoon Eum, Ruby E. Harrison, Mark R. Brown, Michael R. Strand
Summary: This study assessed the expression of insulin-like peptides (ILPs) and ovary ecdysteroidogenic hormone (OEH) in Aedes aegypti during a gonadotrophic cycle and further functionally characterized these peptides to understand their roles in regulating egg formation. The results showed that all ILPs and OEH were expressed during the cycle, and there were differences in their biological activities and insulin- insulin growth factor signaling (IIS) phosphorylation levels.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)
Article
Medical Laboratory Technology
Jason K. Y. Lee, Kendall Cradic, Ravinder J. Singh, JoAnna Jones, Jieli Li
Summary: This study compared the measurement of IGF-1 on four different platforms and found significant variations between them. These variations should be considered when managing patients with pituitary disorders.
CLINICA CHIMICA ACTA
(2023)
Article
Pediatrics
Chi Zhang, Xiaowan Du, Jingjing Li, Junbo Zhang, Guoping Yin
Summary: The study aimed to investigate the effect of daily duration of chronic intermittent hypoxia (CIH) exposure on circulating growth hormone (GH)/insulin-like growth factor-1 (IGF-1) concentrations and body weight changes of premature rats. The results showed that increasing the daily duration of CIH exposure decreased circulating GH/IGF-1 concentrations and caused growth delay in premature rats.
FRONTIERS IN PEDIATRICS
(2023)
Article
Medicine, General & Internal
Aleksandra Matuszyk, Piotr Ceranowicz, Zygmunt Warzecha, Jakub Cieszkowski, Krystyna Galazka, Joanna Bonior, Jolanta Jaworek, Peter Christopher Konturek, Krzysztof Gil, Artur Dembinski
ARCHIVES OF MEDICAL SCIENCE
(2018)
Review
Biochemistry & Molecular Biology
Jolanta Jaworek, Anna Leja-Szpak, Katarzyna Nawrot-Porabka, Joanna Szklarczyk, Michalina Kot, Piotr Pierzchalski, Marta Goralska, Piotr Ceranowicz, Zygmunt Warzecha, Artur Dembinski, Joanna Bonior
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Biochemistry & Molecular Biology
Zygmunt Warzecha, Pawel Sendur, Piotr Ceranowicz, Jakub Cieszkowski, Marcin Dembinski, Ryszard Sendur, Joanna Bonior, Jolanta Jaworek, Tadeusz Ambrozy, Rafal Olszanecki, Beata Kusnierz-Cabala, Tomasz Kaczmarzyk, Romana Tomaszewska, Artur Dembinski
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Biochemistry & Molecular Biology
Joanna Bonior, Piotr Ceranowicz, Ryszard Gajdosz, Beata Kusnierz-Cabala, Piotr Pierzchalski, Zygmunt Warzecha, Artur Dembinski, Michal Pedziwiatr, Michalina Kot, Anna Leja-Szpak, Katarzyna Nawrot-Porabka, Pawel Link-Lenczowski, Rafal Olszanecki, Krzysztof Bartus, Jolanta Jaworek
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Biochemistry & Molecular Biology
Joanna Bonior, Zygmunt Warzecha, Piotr Ceranowicz, Ryszard Gajdosz, Piotr Pierzchalski, Michalina Kot, Anna Leja-Szpak, Katarzyna Nawrot-Porabka, Pawel Link-Lenczowski, Michal Pedziwiatr, Rafal Olszanecki, Krzysztof Bartus, Rafal Trabka, Beata Kusnierz-Cabala, Artur Dembinski, Jolanta Jaworek
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Pharmacology & Pharmacy
Anna Leja-Szpak, Katarzyna Nawrot-Porabka, Marta Goralska, Martyna Jastrzebska, Pawel Link-Lenczowski, Joanna Bonior, Piotr Pierzchalski, Jolanta Jaworek
PHARMACOLOGICAL REPORTS
(2018)
Review
Gastroenterology & Hepatology
Jolanta Jaworek, Barbara Tudek, Pawel Kowalczyk, Michalina Kot, Joanna Szklarczyk, Anna Leja-Szpak, Piotr Pierzchalski, Joanna Bonior, Artur Dembinski, Piotr Ceranowicz, Zygmunt Warzecha, Katarzyna Nawrot-Porabka, Krzysztof Gil
GASTROENTEROLOGY RESEARCH AND PRACTICE
(2018)
Review
Cell Biology
Jan Bilski, Piotr Pierzchalski, Marian Szczepanik, Joanna Bonior, Jerzy A. Zoladz
Summary: Obesity and ageing impose significant strain on the global healthcare system. Age-related sarcopenia and sarcopenic obesity (SO) have substantial impacts on the health of older adults. Dysbiosis and myokine dysfunction may contribute to the development of sarcopenia and SO. Physical activity and proper nutritional support are essential for preventing and slowing down the progression of sarcopenia, especially sarcopenic obesity.
Article
Environmental Sciences
Daria Kostrzewa, Joanna Bonior, Maciej Polak, Alicja Domagala
Summary: The phenomenon of professional migrations in the healthcare sector, especially among physiotherapists in Poland, have not been thoroughly assessed. Economic factors, such as higher earnings and better working conditions, were found to be the main determinants driving both students and practicing physiotherapists to consider migration.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Biology
Gabriela Patla, Agnieszka I. I. Mazur-Bialy, Magdalena Humaj-Grysztar, Joanna Bonior
Summary: This study examined the severity of vulvar pain and its impact on quality of life in a group of Polish women. It was found that vulvodynia mainly affects young, highly educated, and unmarried women, divorcees, and widows. The disease significantly reduces quality of life, mainly due to difficulties in daily activities and decreased sexual satisfaction. The severity of pain is negatively correlated with quality of life. Continued research in this area is recommended.
Article
Biochemistry & Molecular Biology
Ewa Tomaszewska, Malgorzata Swiatkiewicz, Siemowit Muszynski, Janine Donaldson, Katarzyna Ropka-Molik, Marcin B. Arciszewski, Maciej Murawski, Tomasz Schwarz, Piotr Dobrowolski, Sylwia Szymanczyk, Slawomir Dresler, Joanna Bonior
Summary: Chronic pancreatitis (CP) is an irreversible and progressive inflammatory disease. This study aimed to investigate the changes in pro-inflammatory cytokines, antioxidant defense system, and selected serum biochemical parameters in a cerulein-induced CP model in pigs. The study found that repetitive cerulein injections not only led to CP and induced inflammation in the intestine, but also impaired the intestinal barrier.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)