Second AKT: The rise of SGK in cancer signalling

CXCR4 Regulates the Early Extravasation of Metastatic Tumor Cells In Vivo

(2015) Peter Gassmann et al.   NEOPLASIA

mTOR Complex-2 Activates ENaC by Phosphorylating SGK1

(2010) M. Lu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Class IA Phosphatidylinositol 3-Kinase Signaling in Non-small Cell Lung Cancer

(2010) Benjamin Solomon et al.   Journal of Thoracic Oncology

Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3

(2010) Amy Baldwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

(2009) R. J. Shaw   Acta Physiologica

AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer

(2009) Krishna M. Vasudevan et al.   CANCER CELL

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

(2009) A. A. Soukas et al.   GENES & DEVELOPMENT

Identification of Flightless-I as a Substrate of the Cytokine-independent Survival Kinase CISK

(2009) Jun Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: Implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration

(2009) Minho Won et al.   JOURNAL OF HEPATOLOGY

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation

(2009) Rosario Amato et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rictor/TORC2 Regulates Caenorhabditis elegans Fat Storage, Body Size, and Development through sgk-1

(2009) Kevin T Jones et al.   PLOS BIOLOGY

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer

(2008) K. Stemke-Hale et al.   CANCER RESEARCH

Regulation of Ceramide Biosynthesis by TOR Complex 2

(2008) Sofia Aronova et al.   Cell Metabolism

Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34

(2008) Pawan Gulati et al.   Cell Metabolism

Association of SGK1 Gene Polymorphisms with Type 2 Diabetes

(2008) Matthias Schwab et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Long QT Syndrome–Associated Mutations in KCNQ1 and KCNE1 Subunits Disrupt Normal Endosomal Recycling of I Ks Channels

(2008) Guiscard Seebohm et al.   CIRCULATION RESEARCH

EGFR family: Structure physiology signalling and therapeutic targets†

(2008) Antony W. Burgess   GROWTH FACTORS

SGK1 Phosphorylation of IκB Kinase α and p300 Up-regulates NF-κB Activity and IncreasesN-Methyl-D-aspartate Receptor NR2A and NR2B Expression

(2008) Derek J. C. Tai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL

The role of PTEN signaling perturbations in cancer and in targeted therapy

(2008) M Keniry et al.   ONCOGENE

The PTEN–PI3K pathway: of feedbacks and cross-talks

(2008) A Carracedo et al.   ONCOGENE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

Kinase requirements in human cells: I. Comparing kinase requirements across various cell types

(2008) D. A. Grueneberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE