期刊
GREEN CHEMISTRY
卷 20, 期 19, 页码 4428-4432出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8gc02143k
关键词
-
资金
- National Natural Science Foundation of China [21861006]
- Guangxi Natural Science Foundation of China [2016GXNSFEA380001, 2016GXNSFGA380005]
- Ministry of Education of China [IRT_16R15]
- State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University) [CMEMR2017-A02, CMEMR2017-A07]
- BAGUI Scholar Program of Guangxi Province of China [2016A13]
An efficient electrochemical transformation of structurally diverse sulfonyl hydrazides and thiols into thiosulfonates in the presence of ammonium iodide as redox catalyst and electrolyte in acetonitrile at ambient temperature is reported. Transition metal- and oxidant-free conditions are the striking features of this protocol. The in vitro cytotoxicity of all compounds is evaluated by MTT assay against four human cancer cell lines. The results reveal that 3ac and 3ag exhibit potential inhibitory activity against tumor cells. Furthermore, 3ag inhibits cell migration ability and tubulin polymerization in T-24 cells, leading to cell cycle arrest and apoptosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据