Article
Multidisciplinary Sciences
Joshua Rosing, Alex Doyle, AnneMarie Brinda, Madeline Blumenfeld, Emily Lecy, Chelsea Spencer, Joan Dao, Jordan Krieg, Kelton Wilmerding, Disa Sullivan, Sendrea Best, Biswaranjan Mohanty, Jing Wang, Luke A. Johnson, Jerrold L. Vitek, Matthew D. Johnson
Summary: This study investigates the spatiotemporal features of electrically evoked compound action potentials (ECAPs) in and around the subthalamic nucleus (STN) and uses a linear classifier to predict electrode location. The results show that ECAP responses vary with recording and stimulating electrode locations, providing a subject-specific neuroanatomical basis for selecting electrode configurations in DBS therapy for Parkinson's disease.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Aikaterini Gialopsou, Christopher Abel, T. M. James, Thomas Coussens, Mark G. Bason, Reuben Puddy, Francesco Di Lorenzo, Katharina Rolfs, Jens Voigt, Tilmann Sander, Mara Cercignani, Peter Kruger
Summary: Recent progress in optically-pumped magnetometers (OPMs) has enhanced the capabilities of non-invasive brain function mapping through magnetoencephalography, allowing for improved spatial, source localization, and temporal resolution. The closer sensor proximity provided by OPMs has been shown to improve signal tracing and temporal resolution in brain responses to visual stimuli.
SCIENTIFIC REPORTS
(2021)
Article
Otorhinolaryngology
Takwa Gabr, Tarek Eldessouki, Ahmed Hashem, Shimaa Elgamal, Mohamed Zeinhom
Summary: Cochlear implants are a successful alternative for severe-to-profound hearing loss. This study compared visual evoked potentials in children fitted with CIs and normal hearing children, and found that deafness may induce cortical organization in the visual cortex.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2022)
Article
Audiology & Speech-Language Pathology
Jan Dambon, Alexander Mewes, Annika Beyer, Jakob Dambon, Petra Ambrosch, Matthias Hey
Summary: This study investigated the impact of the variation in ECAP threshold in relation to electrode channel on the facilitation properties of spiral ganglion neurons (SGNs). The results showed that the maximum facilitated amplitude was dependent on the ECAP threshold and independent of the electrode channel. Thus, the facilitation paradigm can be a useful tool for studying local temporal processing patterns of SGNs.
Article
Clinical Neurology
Soo-Hyun Park, Choul-Yong Park, Young Joo Shin, Kyoung Sook Jeong, Nam-Hee Kim
Summary: This study found that using 10% contrast stimuli in visual evoked potentials (VEPs) for detecting first-ever optic neuritis (ON) is more sensitive in identifying mild or unremarkable visual impairment compared to conventional high-contrast VEP.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Joanna Daria Dolzycka, Jan Nikadon, Patrick Peter Weis, Cornelia Herbert, Magdalena Formanowicz
Summary: When examining the processing of words from different grammatical classes, using EEG combined with the pseudoword paradigm can provide deeper insight into the neuro- and psycholinguistic dimensions of grammar. In this study, an EEG experiment followed by a behavioral lexical decision task (LDT) revealed different neural and behavioral reactions to verbs and nouns, contributing to the ongoing discussion on the functional processing of words.
BRAIN AND COGNITION
(2023)
Review
Neurosciences
Alexandr Klistorner, Stuart L. Graham
Summary: Multiple sclerosis (MS) is a complex disease of the central nervous system characterized by inflammation, demyelination, neuro-axonal loss, and gliosis. Assessing remyelination along the visual pathway provides valuable insights into the disease progression.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neurosciences
Hyeonhee Roh, Yanjinsuren Otgondemberel, Jeonghyeon Eom, Daniel Kim, Maesoon Im
Summary: This study investigates the electric response features of retinal ganglion cells (RGCs) in rd8 mice with retinal degeneration caused by Crb1 mutation. The results show that different types of RGCs have different electric response features in the early stage of RP, suggesting the importance of genotype- and RGC type-dependent analyses for retinal prosthetic research.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2023)
Article
Audiology & Speech-Language Pathology
Melissa A. Papesh, Alyssa A. Stefl, Frederick J. Gallun, Curtis J. Billings
Summary: The study aimed to investigate auditory performance and cognitive responses in blast-exposed Veterans, revealing that they reported more auditory difficulties but did not necessarily perform worse in behavioral tests. The use of complex stimuli and challenging signal contrasts did not improve the detection ability of these differences.
Article
Engineering, Electrical & Electronic
Charles T. M. Choi, Dong Lin Wu
Summary: This study simulated ECAP based on a CI model using the finite element method and neuron models, and compared the calibrated simulation results with a patient's clinical ECAP measurements. The results showed that the calibrated simulations of ECAPs were consistent with the ECAP measurements, indicating that the simulated ECAP can be used as a reference for patient-specific CI studies.
IEEE TRANSACTIONS ON MAGNETICS
(2022)
Article
Medicine, Research & Experimental
Birte Elisabeth Dietz, Dave Mugan, Quoc Chi Vuong, Ilona Obara
Summary: This study aimed to assess the feasibility of recording ECAPs from the rat spinal cord, demonstrating that the custom-made equipment can successfully record ECAPs. Epidural stimulation predominantly activates large, myelinated fibers, showing significant differences between ECAPT and MT.
Article
Audiology & Speech-Language Pathology
Vignesh Sangu Srinivasan, Bhoopathy Rangappan Munirathinam, Niraj Kumar Singh, Krishna Rajalakshmi
Summary: This study investigated the results of cervical, ocular and masseter vestibular evoked myogenic potentials (cVEMP, oVEMP and mVEMP) among Multiple sclerosis (MS) patients and found that 95.56% of participants had at least one abnormal result. Among the three VEMP sub-types, mVEMP had the highest abnormality rate. Furthermore, there was no significant association between VEMP abnormalities and brainstem symptoms, signs or MRI lesions.
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2023)
Article
Virology
Lais Cristine Delgado da Hora, Lilian Ferreira Muniz, Leonardo Gleygson Angelo Venancio, Karina Paes Advincula, Jessica Dayane da Silva, Diana Babini Lapa de Albuquerque Britto, Democrito de Barros Miranda Filho, Elizabeth B. Brickley, Ricardo Arraes de Alencar Ximenes, Silvio da Silva Caldas Neto, Mariana de Carvalho Leal
Summary: Prenatal exposure to ZIKV can have negative effects on auditory pathways, but CAEP testing can reveal preserved neural function. MRI results show structural changes in the brains of microcephalic children, but CAEP results indicate that these children still have some ability to process sound stimuli.
Letter
Ophthalmology
Ali Nouraeinejad
Summary: Radiation-induced optic neuropathy (RION) is a late complication of radiation therapy for brain and skull base tumors, which can result in total vision loss in one or both eyes. Early detection of RION is crucial due to the absence of visual symptoms and clinical signs at early stages, making the application of visual evoked potential (VEP) as a diagnostic test post-radiation therapy essential for prompt intervention.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Tarciana de Souza Soares, Adriana Berezovsky, Paula Yuri Sacai, Arthur Gustavo Fernandes, Daniel Martins Rocha, Carina Verna, Patricia de Freitas Dotto, Sung Eun Song Watanabe, Solange Rios Salomao
Summary: This study investigated the diagnostic contribution of grating visual acuity (GVA) measured by sweep pattern-reversal visually evoked potentials (SPRVEP) in unexplained visual loss (UVL). The results showed that GVA had good diagnostic validity in discriminating UVL patients from healthy controls and patients with organic visual loss.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)