Structural aspects of binding of α-linked digalactosides to human galectin-1

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Human galectin-3 (Mac-2 antigen): Defining molecular switches of affinity to natural glycoproteins, structural and dynamic aspects of glycan binding by flexible ligand docking and putative regulatory sequences in the proximal promoter region

(2010) Mickaël Krzeminski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor α5β1-integrin

(2010) H Sanchez-Ruderisch et al.   CELL DEATH AND DIFFERENTIATION

Lectin-Based Drug Design: Combined Strategy to Identify Lead Compounds using STD NMR Spectroscopy, Solid-Phase Assays and Cell Binding for a Plant Toxin Model

(2010) João P. Ribeiro et al.   ChemMedChem

How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: Case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane

(2010) Jürgen Kopitz et al.   IUBMB LIFE

Lactose Binding to Galectin-1 Modulates Structural Dynamics, Increases Conformational Entropy, and Occurs with Apparent Negative Cooperativity

(2010) Irina V. Nesmelova et al.   JOURNAL OF MOLECULAR BIOLOGY

Synthesis and screening of a small glycomimetic library for inhibitory activity on medically relevant galactoside-specific lectins in assays of increasing biorelevance

(2010) Sabine André et al.   NEW JOURNAL OF CHEMISTRY

The carbohydrate-binding domain on galectin-1 is more extensive for a complex glycan than for simple saccharides: implications for galectin–glycan interactions at the cell surface

(2009) Michelle C. Miller et al.   BIOCHEMICAL JOURNAL

α-O-Linked Glycopeptide Mimetics: Synthesis, Conformation Analysis, and Interactions with Viscumin, a Galactoside-Binding Model Lectin

(2009) Jesús Jiménez-Barbero et al.   CHEMISTRY-A EUROPEAN JOURNAL

The  -galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain

(2009) M. C Miller et al.   GLYCOBIOLOGY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis

(2009) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Demonstration of protein-protein interaction specificity by NMR chemical shift mapping

(2009) Ponni Rajagopal et al.   PROTEIN SCIENCE

The immunological potential of galectin-1 and -3

(2008) Amy Dhirapong et al.   AUTOIMMUNITY REVIEWS

Galectin–glycan lattices regulate cell-surface glycoprotein organization and signalling: Table 1

(2008) Omai B. Garner et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

1H, 13C, and 15N backbone and side-chain chemical shift assignments for the 29 kDa human galectin-1 protein dimer

(2008) Irina V. Nesmelova et al.   Biomolecular NMR Assignments

Domain versatility in plant AB-toxins: Evidence for a local, pH-dependent rearrangement in the 2γ lectin site of the mistletoe lectin by applying ligand derivatives and modelling

(2008) Marta Jiménez et al.   FEBS LETTERS

Galectin-loaded cells as a platform for the profiling of lectin specificity by fluorescent neoglycoconjugates: A case study on galectins-1 and -3 and the impact of assay setting

(2008) E. M Rapoport et al.   GLYCOBIOLOGY

The Galα1,3Galβ1,4GlcNAc-R (α-Gal) epitope: A carbohydrate of unique evolution and clinical relevance

(2007) Bruce A. Macher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS