Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain

Epidemiological Neuropathology: The MRC Cognitive Function and Aging Study Experience

(2018) Stephen B. Wharton et al.   JOURNAL OF ALZHEIMERS DISEASE

Metallothionein in Brain Disorders

(2017) Daniel Juárez-Rebollar et al.   Oxidative Medicine and Cellular Longevity

The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

(2017) Sudeep Roy et al.   Brain and Behavior

Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective

(2017) Rodrigo E. González-Reyes et al.   Frontiers in Molecular Neuroscience

Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence

(2016) Elizabeth P. Crowe et al.   Frontiers in Aging Neuroscience

A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort

(2015) Julie E. Simpson et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors

(2015) Claire J. Garwood et al.   Molecular Brain

Mammalian MT1 and MT2 metallothioneins differ in their metal binding abilities

(2013) Ester Artells et al.   Metallomics

Metallothionein blocks oxidative DNA damage in vitro

(2012) Wei Qu et al.   ARCHIVES OF TOXICOLOGY

Zinc homeostasis and signaling in glia

(2012) Israel Sekler et al.   GLIA

Metallothionein and brain inflammation

(2011) Yasmina Manso et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Chemistry and biology of mammalian metallothioneins

(2011) Milan Vašák et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice

(2011) Michael W Pankhurst et al.   Journal of Neuroinflammation

Vesicular Zinc Promotes Presynaptic and Inhibits Postsynaptic Long-Term Potentiation of Mossy Fiber-CA3 Synapse

(2011) Enhui Pan et al.   NEURON

Zinc Overload Enhances APP Cleavage and Aβ Deposition in the Alzheimer Mouse Brain

(2010) Chun-Yan Wang et al.   PLoS One

Metallothionein-I+II in neuroprotection

(2009) Mie Ø. Pedersen et al.   BIOFACTORS

Population Variation in Glial Fibrillary Acidic Protein Levels in Brain Ageing: Relationship to Alzheimer-Type Pathology and Dementia

(2009) S.B. Wharton et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Intraneuronal signaling pathways of metallothionein

(2009) Johanne Wirenfeldt Asmussen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain

(2009) J. E. Simpson et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Redefining the Role of Metallothionein within the Injured Brain

(2008) Roger S. Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

Metallothionein in the central nervous system: Roles in protection, regeneration and cognition

(2008) Adrian K. West et al.   NEUROTOXICOLOGY