Glial scar and immune cell involvement in tissue remodeling and repair following acute CNS injuries

IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair

(2013) Gilad Kunis et al.   BRAIN

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

(2013) T. R. Cox et al.   CANCER RESEARCH

The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus

(2013) Michal Schwartz et al.   EMBO JOURNAL

Inflammatory Monocytes Recruited to Allergic Skin Acquire an Anti-inflammatory M2 Phenotype via Basophil-Derived Interleukin-4

(2013) Mayumi Egawa et al.   IMMUNITY

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

Neutrophils Express Oncomodulin and Promote Optic Nerve Regeneration

(2013) T. Kurimoto et al.   JOURNAL OF NEUROSCIENCE

The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain

(2013) Tam Vo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord

(2012) Melania Cusimano et al.   BRAIN

Scar-mediated inhibition and CSPG receptors in the CNS

(2012) Kartavya Sharma et al.   EXPERIMENTAL NEUROLOGY

Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer ‘if’ but ‘how’

(2012) Ravid Shechter et al.   JOURNAL OF PATHOLOGY

Cross-talk between neural stem cells and immune cells: the key to better brain repair?

(2012) Zaal Kokaia et al.   NATURE NEUROSCIENCE

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

(2012) Travis L Dickendesher et al.   NATURE NEUROSCIENCE

CNS sterile injury: just another wound healing?

(2012) Ravid Shechter et al.   TRENDS IN MOLECULAR MEDICINE

Non-Identical Twins – Microglia and Monocyte-Derived Macrophages in Acute Injury and Autoimmune Inflammation

(2012) Steffen Jung et al.   Frontiers in Immunology

Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages

(2011) Anat London et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors

(2011) D. Fisher et al.   JOURNAL OF NEUROSCIENCE

Brain Regeneration in Physiology and Pathology: The Immune Signature Driving Therapeutic Plasticity of Neural Stem Cells

(2011) Gianvito Martino et al.   PHYSIOLOGICAL REVIEWS

The Glial Scar-Monocyte Interplay: A Pivotal Resolution Phase in Spinal Cord Repair

(2011) Ravid Shechter et al.   PLoS One

A Pericyte Origin of Spinal Cord Scar Tissue

(2011) C. Goritz et al.   SCIENCE

Immune modulation by chondroitin sulfate and its degraded disaccharide product in the development of an experimental model of multiple sclerosis

(2010) Juhua Zhou et al.   JOURNAL OF NEUROIMMUNOLOGY

The Extracellular Matrix Glycoprotein Tenascin-C Is Beneficial for Spinal Cord Regeneration

(2010) Jian Chen et al.   MOLECULAR THERAPY

Systemic inflammatory cells fight off neurodegenerative disease

(2010) Michal Schwartz et al.   Nature Reviews Neurology

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Guidance Molecules in Axon Regeneration

(2010) R. J. Giger et al.   Cold Spring Harbor Perspectives in Biology

Extrinsic and intrinsic factors controlling axonal regeneration after spinal cord injury

(2009) Fardad T. Afshari et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury

(2009) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

Depletion of Ly6G/Gr-1 Leukocytes after Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome

(2009) D. P. Stirling et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective and Axon Growth-Promoting Effects following Inflammatory Stimulation on Mature Retinal Ganglion Cells in Mice Depend on Ciliary Neurotrophic Factor and Leukemia Inhibitory Factor

(2009) M. Leibinger et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

The bright side of the glial scar in CNS repair

(2009) Asya Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Oncomodulin links inflammation to optic nerve regeneration

(2009) Y. Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE

The role of tenascin-C in tissue injury and tumorigenesis

(2009) Kim S. Midwood et al.   Journal of Cell Communication and Signaling

Chondroitin sulfate disaccharide stimulates microglia to adopt a novel regulatory phenotype

(2008) Stefanie Ebert et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Requirement of Myeloid Cells for Axon Regeneration

(2008) B. Barrette et al.   JOURNAL OF NEUROSCIENCE

Another Barrier to Regeneration in the CNS: Activated Macrophages Induce Extensive Retraction of Dystrophic Axons through Direct Physical Interactions

(2008) K. P. Horn et al.   JOURNAL OF NEUROSCIENCE

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation

(2008) Asya Rolls et al.   PLOS MEDICINE

A ‘GAG’ reflex prevents repair of the damaged CNS

(2007) Larry S. Sherman et al.   TRENDS IN NEUROSCIENCES