The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes
出版年份 2014 全文链接
标题
The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes
作者
关键词
-
出版物
GLIA
Volume 62, Issue 5, Pages 725-735
出版商
Wiley
发表日期
2014-02-17
DOI
10.1002/glia.22637
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
- (2013) Iain B McInnes et al. ANNALS OF THE RHEUMATIC DISEASES
- Treating multiple sclerosis with monoclonal antibodies: a 2013 update
- (2013) Annika Deiß et al. Expert Review of Neurotherapeutics
- Secukinumab in the Treatment of Noninfectious Uveitis: Results of Three Randomized, Controlled Clinical Trials
- (2013) Andrew D. Dick et al. OPHTHALMOLOGY
- Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study
- (2012) Mark C Genovese et al. ANNALS OF THE RHEUMATIC DISEASES
- Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke
- (2012) M. Gelderblom et al. BLOOD
- Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomised, double-blind, placebo-controlled, phase II regimen-finding study
- (2012) P. Rich et al. BRITISH JOURNAL OF DERMATOLOGY
- Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study
- (2012) K.A. Papp et al. BRITISH JOURNAL OF DERMATOLOGY
- Regulation of CCL20 expression in astrocytes by IL-6 and IL-17
- (2012) Gordon P. Meares et al. GLIA
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
- (2012) Wolfgang Hueber et al. GUT
- Analysis of Proinflammatory and Anti-Inflammatory Cytokine Serum Concentrations in Patients With Multiple Sclerosis by Using a Multiplexed Immunoassay
- (2011) Thomas B. Martins et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Gp130-Dependent Astrocytic Survival Is Critical for the Control of Autoimmune Central Nervous System Inflammation
- (2011) F. Haroon et al. JOURNAL OF IMMUNOLOGY
- IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease
- (2011) Jarod Zepp et al. TRENDS IN IMMUNOLOGY
- IL-6: Regulator of Treg/Th17 balance
- (2010) Akihiro Kimura et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis
- (2010) Zizhen Kang et al. IMMUNITY
- IL-17 Enhancement of the IL-6 Signaling Cascade in Astrocytes
- (2010) X. Ma et al. JOURNAL OF IMMUNOLOGY
- Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis
- (2010) Manjeet K. Paintlia et al. JOURNAL OF NEUROCHEMISTRY
- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
- (2010) W. Hueber et al. Science Translational Medicine
- Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells
- (2010) Rie Miyamoto et al. ARTHRITIS RESEARCH & THERAPY
- T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β
- (2009) Luca Durelli et al. ANNALS OF NEUROLOGY
- Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies
- (2009) Nemanja Damjanov et al. ARTHRITIS AND RHEUMATISM
- Cellular mechanisms of IL-17-induced blood-brain barrier disruption
- (2009) Jula Huppert et al. FASEB JOURNAL
- TLR2 Deficiency Leads to Increased Th17 Infiltrates in Experimental Brain Abscesses
- (2009) J. R. Nichols et al. JOURNAL OF IMMUNOLOGY
- Retinal astrocytes respond to IL-17 differently than retinal pigment epithelial cells
- (2009) Yan Ke et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Interleukin-17 in transverse myelitis and multiple sclerosis
- (2008) J GRABER et al. JOURNAL OF NEUROIMMUNOLOGY
- Production and functions of IL-17 in microglia
- (2008) Jun Kawanokuchi et al. JOURNAL OF NEUROIMMUNOLOGY
- Increase of CD4+TNFα+IL-2−T cells in cerebrospinal fluid of multiple sclerosis patients
- (2008) N Shi et al. Multiple Sclerosis Journal
- Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis
- (2007) John S. Tzartos et al. AMERICAN JOURNAL OF PATHOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More