Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury

Critical Role of Connexin 43 in Secondary Expansion of Traumatic Spinal Cord Injury

(2012) C. Huang et al.   JOURNAL OF NEUROSCIENCE

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

(2012) Robert E Sorge et al.   NATURE MEDICINE

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 1

(2011) Julius J. Matasi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Neuronal Hyperexcitability: A Substrate for Central Neuropathic Pain After Spinal Cord Injury

(2011) Young Seob Gwak et al.   Current Pain and Headache Reports

Role of gap junctions in chronic pain

(2011) Ann Wu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Intrathecal injection of carbenoxolone, a gap junction decoupler, attenuates the induction of below-level neuropathic pain after spinal cord injury in rats

(2010) Dae-Hyun Roh et al.   EXPERIMENTAL NEUROLOGY

P2X7-Dependent Release of Interleukin-1  and Nociception in the Spinal Cord following Lipopolysaccharide

(2010) A. K. Clark et al.   JOURNAL OF NEUROSCIENCE

Spinal Microglial Motility is Independent of Neuronal Activity and Plasticity in Adult Mice

(2010) Tao Chen et al.   Molecular Pain

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury

(2010) Ephron S Rosenzweig et al.   NATURE NEUROSCIENCE

Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture

(2010) Nanna Goldman et al.   NATURE NEUROSCIENCE

Minocycline prevents impaired glial glutamate uptake in the spinal sensory synapses of neuropathic rats

(2010) H. Nie et al.   NEUROSCIENCE

Targeting astrocyte signaling for chronic pain

(2010) Yong-Jing Gao et al.   Neurotherapeutics

FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels

(2010) J. M. Garre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pannexin 1: The Molecular Substrate of Astrocyte "Hemichannels"

(2009) R. Iglesias et al.   JOURNAL OF NEUROSCIENCE

Gait Analysis in Normal and Spinal Contused Mice Using the TreadScan System

(2009) Jason E. Beare et al.   JOURNAL OF NEUROTRAUMA

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(2009) Andrew M. Tan et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Behavioral Phenotypes of Mice Lacking Purinergic P2X4 Receptors in Acute and Chronic Pain Assays

(2009) Makoto Tsuda et al.   Molecular Pain

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

(2009) W. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological and pathological functions of P2X7 receptor in the spinal cord

(2009) Maria Luisa Cotrina et al.   Purinergic Signalling

Purinergic signalling in inflammation of the central nervous system

(2009) Francesco Di Virgilio et al.   TRENDS IN NEUROSCIENCES

Mechanisms of chronic central neuropathic pain after spinal cord injury

(2008) Claire E. Hulsebosch et al.   BRAIN RESEARCH REVIEWS

Connexin43 Mimetic Peptides Reduce Swelling, Astrogliosis, and Neuronal Cell Death after Spinal Cord Injury

(2008) Simon J. O'Carroll et al.   CELL COMMUNICATION AND ADHESION

P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

(2008) H. Tozaki-Saitoh et al.   JOURNAL OF NEUROSCIENCE

P2Y12 Receptor Upregulation in Activated Microglia Is a Gateway of p38 Signaling and Neuropathic Pain

(2008) K. Kobayashi et al.   JOURNAL OF NEUROSCIENCE

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1 , Interleukin-6, and Tumor Necrosis Factor-  in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

(2008) Y. Kawasaki et al.   JOURNAL OF NEUROSCIENCE

Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury

(2008) Michael Cronin et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Altered ATP Release and Metabolism in Dorsal Root Ganglia of Neuropathic Rats

(2008) Yoshizo Matsuka et al.   Molecular Pain

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE